Buserelin saldhig - description iyo codsiga muuqaalada

Doorashada daroogada hormoon waa in lagu saleeyaa baadhitaan taxadir leh calaamadaha iyo aqoonsiga taxadir leh ee halista waxyeellooyinka.

Diyaarinta "Buserelin Depot" hoosaysa barbar kale oo ay ku oolnimada sare iyo jaaniska hooseeyo calaamadaha loo kasin. Isagu waa xubin ka mid ah wakiilada anticancer hormoon.

tallaabada pharmacological daroogada

tallaabo ka kooban yahay antigonadotropnym buserelin, anti-androgenic, anti-estrogen, saamaynta anti-buro. walax Drug "Buserelin Depot" by xidho tartan receptors unugyada secreting factor gonadotropin-daayo (ay ku jiraan qaab-dhismeedka xuubka jilibka qanjirka pituitary ee).

In marxaladda ugu horeysay talooyin daroogada ayaa lagu arkay korodhka transient in fiirsashada of LH iyo FSH (hormone gonadotropic), qoondeeyey by pituitary ee, taas oo horseedaysa in ay kor u kacay content Gomonov taranka. 14 Ka dib markii - 21 maalmood ku furid ka dhigan tahay shaqo gonadotropic by jawaabcelinyo xun, taas oo horseedaysa hoos u weyn ee LH iyo FSH, iyo, iyada oo sababtu tahay, iyo hoos u wax soo saarka ee hormoonnada jinsiga. Sayidka, fiirsashada testosterone lab hoos, oo waxay gaadhaysaa xataa heer kaas oo la aasaasay ka dib markii orchiectomy (castration caafimaad). Haweenka daroogada saamayn "Buserelin Depot" waxaa la yareeyo heerka estradioda saarka hadda jira muddo posklimaktericheskom.

Isticmaalka daroogada "Buserelin Depot"

Waxaa loo isticmaalaa in lagu daaweeyo kansarka qanjirka 'prostate', mararka qaarkood, loo isticmaalo si loo xakameeyo soo saarka testosterone ee xiniinyaha. Sidoo kale loo isticmaalaa in lagu daaweeyo kansarka naasaha (cudurada hormoonka-ku-tiirsane, taas oo ah waxa lagu gartaa-soo-saarka sare ee estrogens ama u muuqataa in endometriosis). cudurrada kale, daaweynta "buserelina Depot": fibroids, makaanka, kelyaha gooba, qabashada barnaamijka IVF ee daaweynta dhalmo la'aan.

Sababo gaar ah iyo talooyin

Diidmo, orchiectomy, uurka, nuujinta. Taxadarka qaadashada daroogada ee cudurada of mareenka kaadida heerka of metastasis vertebral, hypertension, diabetes, iyo niyad-jab. Buserelin saldhig iyo uurka - fikradaha is gayin.

waxyeellooyin

Bukaanka ayaa laga yaabaa in ay ka cawdaan qidmeyntiibulshada on qayb ka mid ah nidaamka dhexe ee habdhiska qaab madax xanuun, isku yaacsanaan, hurdo la'aan, xusuus la'aan, hoos u fiirsashada, dawakhaad, xasilooni dareen, iyo mararka qaarkood niyadjabka. Waxaa la dareemi karaa tinnitus ama cadaadis on bu'da, ee aragti cawlan ama dhagaysiga. Waxaa inta badan noqon kartaa "dareenka gubashada ah." Toddobaadka ugu horreeya ee daaweynta haweenka arkay psevdomenstruatsiya, markaas dhigay qallayl siilka, suurto gal demineralization lafta, libido hoos. In ragga, cudurka la sii dartay laga yaabaa in marka hore 2 - 3 todobaad, ama iyaga ula muuqda gynecomastia, awoodba dhimay. Saxda ah isku dhici kara: anorexia, xanuunada dyspeptic. Buserelin saldhig iyo qamriga waxay ku leheyn. In bukaanka qaba dhiig-karka kordhin kartaa cadaadis, garaaca wadnaha. From cadaanyo dhacaan: cuncun, finan, bronchospasm, shoog. Beddelidda tilmaamayaasha shaybaarka: dyslipidemia, hyperglycemia, korodhsan transaminases iyo bilirubin, Torombositobiiniya iyo leukopenia.

The mabaadiida daroogada

Maamulka muruqyada dhexdooda, maamula isla markiiba ka dib diyaarinta joojinta.

- markii buro prostate 4 toddobaad kasta ee 4.2 mg.

- Endometriosis - waxaa soo bandhigay 4 bilood gudahood.

- la myom makaanka -3 bilood.

- dhalmo la'aan - 4.2 mg.

Maamulka Intranasal:

- for daawaynta cudurada haween ah kor lagu sharaxay - maamulay si dalool sanka 900 mg / maalintiiba (hal dose, 3 jeer maalintii), laga bilaabo 1 - 2 days of wareegga caadada.

- dhalmo la'aan 600 mg / maalintiiba, 1 dose in dalool sanka afar jeer maalintii. Haddii si xoog leh ka muujiyay Go'doominta nidaamka taranka, dose waa la dhimay ilaa 2 jeer.

qoraalada Qaar ka mid ah:

- Dawaynta kansarka qanjirka 'prostate' waa la fuliyay nolosha oo dhan,

- daawooyinka anti-antiandrogen maamula mudo ah 2 todobaad. iyo 2 toddobaad. daaweynta la buserelin, ka hortagtaa dhibaatooyinka waxa dhici kara in inta lagu guda jiro toddobaadyada ugu horeeya ee daaweynta,

- in xilliga ugu horreeya ee daaweynta ee dumarka u muuqan kara cyst ugxansiduhu,

- Waa in laga hortago uurka iyo uureysiga qaata daawada si loo daaweeyo buserelin, laakiin 2 bilood ee ugu horreeya waa lagama maarmaan in la isticmaalo habab aan ahayn hormoon ah ee ka hortagga;

- si wanaagsan u saameyneysaa daaweynta daroogada ee endometriosis ka qalliin iyadoo la yareynayo inta jeer ee soo noqoshada.

Dhexgalka daroogooyinka kale

Buserelin yaraynaysaa saamaynta daroogada hypoglycemic. Waxay u keeni kartaa hyperstimulation ugxansiduhu, haddii lala isticmaalo daawooyinka ka kooban hormoonnada jinsiga.