MMF (mofetil mycophenolate): description, analogs

mofetil Mycophenolate (INN Mycophenolic acid) waxaa ka mid ah kooxda immunosuppressants. Ha ka fikiro si aynu si faahfaahsan xaaladaha ku jira kuwaas oo ay tahay lagama maarmaan in la isticmaalo daroogada, waxa jira sababo si ay isticmaalka iyo waxyeelo.

Intaa waxaa dheer, waxaan u ogaato haddii ay jiraan in Farmashiiste hab casri ah oo la mid ah.

Summary

mofetil mycophenolate waxaa laga heli karaa qaab kaabsoosha gelatin adag in foolmaroodi ah budada cad gudaha.

Soo iibso daawooyinka farmasiyada oo keli ah haddii aad leedahay warqad dhakhtar.

nolosha shelf waa laba sannadood ka dhigan tahay. Keep it waa in kor heerkulka ilaa 25 digrii ah.

Si aad u leeyihiin waxgarasho muuqaal ah sida aan ayaa ka fiirsaneysa inay looks daroogada (mofetil mycophenolate), photo kor u adeegi tusaale ahaan lagu sharraxo.

daroogada

Mid ka mid ah hab kaabsal ku jira 250 mg ee xarunta firfircoon (mofetil mycophenolate). Intaa waxaa dheer, qaybaha joogo iyo kaabayaal ah, sida sodium croscarmellose, cellulose mikrokristallin, povidone iyo milmahayn magnesium.

Pharmacokinetics

daroogada ka dib waa ay nuugista dhamaystiran oo dhamaystiran shiid presystemic. Xaaladdan oo kale, midda walax firfircoon ee plasma waxaa lagu arkay ay sabab u tahay isbadal deg deg ah galay metabolites firfircoon.

Macnaheedu raaca kaadida iyo saxarada.

Tilmaamayaasha

Xaaladaha qaarkood, waxay isticmaalaan ee mofetil mycophenolate? Tilmaamaha loogu isticmaalo si deg deg ah uga jawaabtid su'aashan.

Dhakhaatiirta kuu qori qaadashada daroogada ee prophylaxis ee diidmada xubin ba'an ee bukaanka ka dib markii xubin badalida kelyaha, beerka ama wadnaha.

sababo

Ma jiraan xaalado badan halka isticmaalka daroogada gebi ahaanba la mamnuucay "mofetil Mycophenolate". Kuwaas waxaa ka mid joogitaanka diidmo bukaanka inay maal ugu weyn ee firfircoon ama waxyaalo kale oo ka mid ah wakiilka, iyo sidoo kale xilliga uurka iyo nuujinta.

The quseeya ammaanka iyo daroogada ee lagu daweeyo carruurta aan la aqoonsaday, si ha u isticmaalin in Caruurta.

waxyeellooyin

mofetil Mycophenolate awoodaan in ay ka cadhaysiiyaan waxyeelo qaar ka mid ah. Its isticmaalka isku dhafan oo Cyclosporine iyo corticosteroids keeni kartaa shuban, matag, leukopenia iyo sepsis. Xaaladaha qaarkood, waxaa jiray horumarinta lymphoma iyo carcinogenic kale, gaar ahaan maqaarka.

Waxaa intaa dheer, in dhammaan dadka qaba beerista waxay halis ugu jiraan cudurada faafa, kuwaasi oo ay kaga xanaajiyeen by wareer fursad. The ugu iyaga ka mid ah waxay kala yihiin herpes, candidiasis iyo cytomegalovirus.

Dareen-celinta kale ee loo kasin isu muujin karo qaab shingles, infekshinka kaadida, rhinopharyngitis, hyperthermia, beerka aan caadi ahayn, esophagitis, dhiigbaxa caloosha, cudurada of aagga sare ee neefsashada, qufac, madax xanuun, caloosha, daal, hogaga, candidiasis afka , ganaca, pancytopenia, neutropenia, iyo wixii la mid ah.

Waxaa jira hanjabaad u daran iyo mararka qaarkood ifafaale xitaa halis ah sida qaaxada, endocarditis bakteeriyada, cudurada atypical Gronland.

Qadarka Qaadashada iyo Maamulka

Sida loo isticmaalo daroogada "mofetil Mycophenolate"? Tilmaamaha ku rakiban yihiin, waxay bixisaa macluumaadka soo socda.

Wixii ka hortaga diidmada kelyaha. Marka ugu horeeysa ee wakiilka in la keeno galay jidhka 72 saacadood gudahood ka dib marka xubin badalida sameeyay. Ka dibna, bukaanka u baahan doontaa inaad qaadato 1 g laba jeer hab maalintii.

Sayidka mofetil mycophenolate waxaa badanaa maamula isku dhafan oo corticosteroids iyo cyclosporin.

Wixii ka hortaga diidmada wadnaha. Marka ugu horeeysa waa in la qaato aan ka dambayn 5 maalmood qaliin lagu sameeyay ka dib. Ka dibna waxa qadar lagama maarmaanka ah ee alaabta waa 1.5 g laba jeer maalintii

badinta

Data on badinta daroogada, "mofetil mycophenolate," aan la heli karin.

Waxaa loola jeedaa in aysan macquul aheyn in lean jidhka ka by kelyaha. Daawooyinka isku xidhxidhaan acids bile (cholestyramine) fududeyn kara saarista shaqeeyo IFC ah, kordhinta ay Digo.

Features of codsiga

Marka la ogaado of neutropenia bukaanka waa la dhimi dose oo si dhow ula socdaan xaaladda caafimaad ee bukaan-socodka ama kala go'do daaweynta mofetil mycophenolate.

In joogitaanka daran renal failure raaga waa in si dhow ula socdaan gobolka ee caafimaadka iyo kama badna hab dose ugu badnaan, taas oo haddii ay taasi ka dhigan tahay in 2 g maalintii.

bukaanada waayeelka ah (65 sano) talinayaa isticmaalka of 1 g of daroogada, 2 jeer maalintii.

Warbixin ku saabsan waxtarka of wakiilada ee daaweynta bukaannada qaba kelyaha ayaa qaliin beerka ama wadnaha, waxaa ka maqan. Sidoo kale, waxaa jira macluumaad ku saabsan sida daroogada waa ku ool ah bukaanka qaba lesions beerka kuwaas oo maray badalida qalbigiisiina waxaa laga dhigay.

tallaabooyin taxaddar

Si kastaba ha ahaatee ma furi karaan kaabsal ee diyaarinta. Waa inay ka fogaadaan xiriir toos ah la budada ah, waayo, kaasu neefsasho, xiriir la maqaarka ama xub-axaleedka. Haddii, si kastaba ha ahaatee, waxaa dhacday, waa in isla markiiba ku dhaq meesha ay dhibaatadu saameysey saabuun iyo biyo.

analogues lacagaha

Ma jiraan daawooyinka bedeli karo sheyga "mofetil Mycophenolate"? Analogs, dabcan, waxaa jira. Waxay leeyihiin INN isku mid ah (International noocan Name), ama code ATC. waxay noqon doontaa keliya spectrum yar kala duwan ee kharashka hawsha iyo lacag caddaan ah.

The ugu caansan yihiin dawooyinka soo socda:

• "Baksmun". Waxaa loo adeegsaday in lagu daro Cyclosporine iyo corticosteroids ka hortagga ah ee diidmada ah ee wadnaha, beerka ama kelyaha ka dib markii xubin badalida.
• "Zenapax." Waxa loo isticmaalaa si looga hortago in diidmada ah xubin kelyaha ah isku dhafan oo GCS Cyclosporine.
• "Imusporin". Loo isticmaalo ka hortagga iyo daaweynta xubnaha transplanted iyo dhuuxa lafaha iyo sidoo kale in rheumatoid arthritis, uveitis qoomiyadda, cudurka Behcet ee, lupus erythematosus oo nidaamsan, iyo cudurrada kale ee.
• "Imufet". Sidoo kale daroogada ugu weyn, wakiilka maamula isku dhafan oo corticosteroids iyo cyclosporin ka hortagga diidmada kelyaha ah transplanted ama beerka.
• "Layfmun". Tool ayaa spectrum balaadhan oo ah tallaabo. Waxaa loo isticmaali karaa ka hortagga iyo daweynta diidmada xubnaha transplanted by dhuuxa jidhka iyo lafta, iyo sidoo kale arthritis, nephrotic syndrome, foomamka firfircoon ee lupus erythematosus oo nidaamsan, cudurka Behcet ee, uveitis qoomiyadda iyo cudurrada kale ee.
• "Mifenaks". Tilmaamayaasha loogu isticmaalo waa la mid ah sida in ka mid ah hab ugu muhiimsan.
• "Mifortik". Loogu talagalay in looga hortago in diidmada kelyaha transplanted.
• "Mofilet". Tilmaamayaasha iyo isticmaalka la mid ah la mofetil mycophenolate yihiin.
• "Panimun". Waxaa loo adeegsaday in xubin badalida ee sambabada, wadnaha, kelyaha, dhuuxa lafta, beeryarada, iyo sidoo kale in cudurada qaarkood.
• "CellCept." Waxaa la qoondeeyey karaa marka xubin kelyaha ah.
• "Sertikan". Waxaa la tilmaamay for beerista kelyaha ama bukaanka wadnaha halis difaaca dhexdhexaad ah ama hooseeyo.
• "Tsikloral". Waxaa lala isticmaalaa daawooyinka kale ee xubnaha.
• "Ekvoral". Waxa loo isticmaalaa in xubin badalida ee xubnaha parenchymal, iyo sidoo kale ka hortagga ee diidmada ka dib markii xubin badalida.

In kasta oo xaqiiqda ah in dhammaan waxay leeyihiin nooc ka mid ah garoomada, ka hor inta uu bedelay daroogada weyn oo kale oo kasta, waa in aad marka hore la tashato, iyo dhakhtarkaaga la tasho.