Professor Skulachev: indhaha lagu dhibciyo. Indhaha lagu dhibciyo "Vizomitin" (dhibciyo Skulachev) ah ayaa eegaya, qiimaha, guide

Time ma istaagaan, iyo qaabkeeda oo dhan nolosha nafleyda on Earth waxaa waajib ah in isbedel gaboobaya. Shaacbaxaya geedi socodka gaboobaya ogaado muuqaalka qanacsanayn u shaqeeyo gaar ah iyo kuwa kale, dhacdo ee mooshinka lagu jiro neefsashada degdeg ah, dyspnea, foororsaday Dhehana iyo xakamaynta dhaqdhaqaaqa. Intaas waxaa sii dheer, aragti dilaacda.

Waxaa jira ra'yi, taas oo, kadis ah, waa mid caadi ah in geeddi-socodka gaboobaya ma ahan wax in la joojiyo, iyo hoos u suurta galayn. Professor Skulachev, indhaha lagu dhibciyo oo si dhab ah u yihiin saamaynta mucjiso ah, dhaqmayso barta kale ee view.

Dabcan, da '- waa hab dabiici ah, laakiin sabab qaar ka mid ah ma u dhigi kartaa? Gabowga ma aha sabab la'aan. In goobada of saynisyahano ku lug leh geeddi-socodka gaboobaya ee jidhka bini'aadamka, waxaa jira aragti xooggan oo ah in Silsilad DNA our duubay barnaamij gaar ah oo mas'uul ka yahay geedi socodka gaboobaya ee jirka. Markay da 'gaar ah, waxaa jira hawshooda u ah barnaamijka, kaas oo ugu dambeyntii keenta in lama huraan ah - dhimashada.

Waa maxay khatarta ku ah indhaha gaboobaya

Ku xadgudubka geedi socodkii aragti muuqaal ah waa mid ka mid ah calaamadaha ah ee gabow. No, dabcan, waxaad kula kulmi kartaa dadka qaba gobolka weyn ee caafimaadka, taas oo ku filan mucaaradka firfircoon oo buuxa oo dhan cayn kasta oo ah cudurada of da 'weyn, laakiin haddii qof si lama filaan ah lumiso aragga, ama si weyn u dari doonto, xitaa "geesi" sida a noqdo xukumay naafo ah.

Inta badan Overwhelming cudurada indhaha yeeshaan muddo aad u tartiib ah. Iyadoo da'da, qanjirka lacrimal waxaa ka shaqeeya in ka yar, iyo this waxaa weeyaan hoos u dhac ku ah wax soo saarka iyo tayada ilmada. Waxa uu noqonayaa mid la dareemi karo ka dib 40 sano jir, laakiin waa ay dhici kartaa oo ka dib markii 30.

Like, waxa this? Waa wax caadi ah in la da 'noqdo khafiif ah plyonochku ilaaliya indhaha sii kordheysa dhici microtrauma corneal iyo dhaawac, cudurada bararka, in indhuhu ku daalaan si dhakhso ah. In microchanges sida dheeraad ah ayaa aasaas u ah horumarka cudurada dheeraad ah oo halis ah sida cataract, kordhay cadaadiska intraocular horumarinta glaucoma, waxaa laga yaabaa in ay bilaabaan isbedel side ah ileyska iyo dareemayaasha optic ka soo gaartay horumar of aragga. Laakiin ha ka baqin in cuduradan laga yaabaa inuu dhaco, iyo dhammaan in jiffy ah. Horumarkooda yahay mid gaabis ah oo si tartiib ah.

Tani ayaa riixay xaqiiqda ah in professor ku go'aansaday in la abuuro dhibcood isha Skulachev. Rogaal celinayo si iyaga taariikhda aad u wanaagsan. A aad u weyn, haddii aanay weyn, tirada bukaannada indhaha mar kale fursad u helaan a fiirin cad-weershe ah ee aduunka iyada oo aan qalliinka. Iyo in soo hindiseen dhibcood isha Professor Skulachev mahad, qiimaha taas oo ah in ka badan dimoqraadi ah.

Antioksidanter sida mitochondrial

In State Moscow Jaamacadda. Jaamacadda tan iyo 2005, waxa uu bilaabay mashruuc cilmi-baaris ku saabsan horumarka daawooyinka loogu talagalay in ay dib u dhigto hawshooda u ah ee barnaamijka iyo hoos-socodka gaboobay a. Under hanuunka V. P. Skulacheva, Academician of Academy Ruush ee Sciences, saynisyahan biochemist kuwaas oo muddo ka badan afartan sano ku hawlan cilmi ah hababka ka dhacaya mitochondria, ayaa la Been abuurtay nooc cusub oo ka mid ah sinji - antioksidanter nooca mitochondrial.

Iyada oo waxbarasho ka dib markii war abuurashadoodii ugu horeysay ee tan kiimikada nooca, saynisyahano helay in antioksidanter mitochondrial Kobocii, iyo xaaladaha qaarkood beddeli habka cudurada indhaha ee xoolaha ee tijaabo ah. shaqo badan ku abuurtay ee daroogada cusub oo ku salaysan antioksidanter mitochondrial la sameeyo dhowr sano ka dib, iyo dhibicyo isha Professor Skulachev waxaa soo bandhigay magaca "Vizomitin".

Bal aynu eegno mid ka mid ah calaamadaha ugu horeeya ee gaboobaya isha - cillad da'da la xiriira ee qanjirka lacrimal. Maxaa dhacaya da'da? Iyadoo da'da uu jiro hoos u dhac of sifooyinka tayo iyo tiro ahaanba dheecaanka lacrimal iyo, sidaas awgeed, horumarinta syndrome ee "indhaha qalalan". Waxaa la muujiyey by dareen hore ee raaxo indhaha, dareen ah badar ee ciid ama jirka shisheeye yar, iyo horumarka tartiib ah cudurka la kulmi karaan cawaaqib ka sii daran.

Ogsoonow in dhibic ka tirey hadda ka jira suuqa dawooyinka ee tiro badan. Sidoo kale waaweyn iyo xaddiga daroogada loogu talagalay daaweynta ee daliilka calaamadaha inta lagu guda jiro "isha qalalan", laakiin ku dhowaad dhammaan iyaga (ama tirada ugu badan) oo ah waa analoogga ah isku dardaro ee dareeraha jeex aadanaha. Ay khasaaro ugu muhiimsan waa in bukaanka uu leeyahay si ay u isticmaalaan daroogada, kuwaas oo min 10 ilaa 20-25 jeer maalintii, tan iyo isticmaalka loogu talagalay kaliya ee dib u soo celinta content dheecaan jeex caadi ah in isha.

Laboratory iyo kiliinikada imtixaanada

Dhibic ugu dambeeyay "Vizomitin" aasaas kala duwan yihiin mabda'a hawlgalka daawooyinka la mid ah loo isticmaalo daweynta ee isha qalalan. Waxay sabab u yihiin mid aad ee cudurka, horumarinta hawlaha qanjirka lacrimal iyo joojinta iyada isbedel side. Intaas waxaa sii dheer, in dhibco lagu buufiyo waxay leeyihiin saameyn la mid ah sida dhibco ilmada macmal cataract ku salaysan.

xaalad Tani - ma ahan oo kaliya qoraal ah oo afka baarkiisa, laakiin xaqiiqda dhab aasaasay. Professor Skulachev indhaha lagu dhibciyo si xoog leh cilmi-baaris ah ee xoolaha iyo tijaabooyin caafimaad ee daroogada lagu qabtay xarumaha badan isha: at the Department of indhaha (Ruush University Medical State) oo ka tirsan machadka cilmibaadhista ee Cudurada Eye Helmholtz.

Natiijada helay in cilmiga iyo tijaabo, natiijooyinka waa kuwo yididiilo leh. Professor Skulachev, dhibco lagu shubo indhaha, kuwaas oo suuq hoos magaca "Vizomitin", ayaa sheegay in ay wax badan ka waxtar badan daroogada la mid ah loo isticmaalo daweynta iyo tirtiridda ka mid ah calaamadaha waa syndrome ee "isha qalalan". Waxaa intaa dheer, waxaa la ogaadaa in dhibaatooyinka soo raaca inta lagu jiro daaweynta leh, kuwaas oo dhibcood ee bukaan ayaa la arkay.

Iyada oo ku saleysan natiijooyinka daraasaadka kuwan, daroogada waxaa ka diiwaan gashan Wasaaradda Caafimaadka iyo Horumarinta Bulshada ee December 2011 iyada oo loo adeegsanayo keratoprotektornogo loo yaqaan "Vizomitin", ama indhaha lagu dhibciyo Skulachev. Halkee si ay u iibsadaan daawada maanta? Tan iyo xagaagii 2012, waxa uu u muuqday in farmasiiyada tafaariiqda network ee dalka.

Dabcan, sida wax daroogada kale oo cusub oo la walax firfircoon oo horey loo yaqaaney "Vizomitin" daayay oo keliya by qoro. Waxaan ka iibsan kartaa iyada oo aan indhaha lagu dhibciyo Skulachev? Halkee si ay u soo iibsadaan, haddii aan la karinayo? Ha door biday in ay tricks, iyo xiriir indhaha dhigata. qoro daroogada fasax ma loo baahan yahay in tixraac ceebaha - waxaa inta badan go'aamisa ay ujeedada la doonayey, kuwaas oo, ee jeedo, waxa ay tilmaamaysaa saamaynta wanaagsan ee codsiga.

daahfurka si dhab ah u gaar ah A by Professor Skulachev sameeyey. dhibciyo Eye, taas oo u eegay wanaag keliya kulmi runtii leeyihiin saamayn mucjisada ah. Waayo, fulinta iyo waxbarashada clinical waa in ay indhaha ma aha oo kaliya in Russia laakiin sidoo kale adduunka oo dhan. daroogada Tani mawduuca shirar gaar ah oo siminaaro si ay indhaha kasta macluumaadka.

Ina keena aynu deggan faahfaahin dheeraad ah ee "Vizomitin" diyaarinta. Tilmaamaha loogu isticmaalo siin karaa macluumaad badan oo xiiso leh.

Description of diyaarinta

Tani waa hab ku ool ah oo hufan, sida macquulka ah midab xoogaa ama in yar oo dareere ah opalescent. Plastohinonildetsiltrifenilfosfoniya walax firfircoon waa bromide, taas oo 1 ml of diyaarinta ka kooban 0,155 micrograms. Sida excipients isticmaalo chloride benzalkonium, hypromellose, chloride sodium iyo kuwa kale. Daroogada waxaa iska leh wakiilada pharmacotherapeutic kooxda keratoprotektornyh, iyo sidoo kale kooxda ka mid ah antioksidant.

Data on pharmacodynamics

xarunta bromide Plastohinonildetsiltrifenilfosfoniya waa derivative ah plastoquinone oo dhex yeero silsilad linker la xidhiidha triphenylphosphine haraaga ah. Sida Dr Skulachev sheegay in indhaha lagu dhibciyo (qiimaha iyaga sababtoo ah cheapness qaraabo ah ereygu wuxuu ahaa ee xarunta tani ma aha sare) ee ay isugu soo urureen nanomolar awood u muujiyo waxqabad aad u dheer antioxidant leh saamayn dhiirrigelin sare on geedi socodka slezoobrazovaniya in la kordhiyo xasiloonida jirka sameeyay film ka ilmaysiisa iyo sidoo kale saamayn ku geeddi socodka epitealizatsii.

data pharmacokinetic

Si aad u taariikhda, waa in la sheegay in tiro ka mid ah waxbarashada pharmacokinetic aan la sameeyay in aadanuhu. Marka la eego cilmiga xoolaha pre-clinical, qaybinta dhibco walax firfircoon u shaqeeyo ayaa lagu arkay 2 maalmood ka dib markii maamulka afka ama parenteral. Joogitaanka plastohinonildetsiltrifenilfosfoniya bromide la diiwaan ee ugu badan ee unugyada kelyaha iyo unugyada beerka, wadnaha ka dib markii 1 saac ka dib markii maamulka. Waxaa la arkay in walaxda si dhakhso ah u sakhiray in ay burbur isticmaalaya falgalka iyo cadaato awood u xidhnahay covalent la borotiinada.

Tilmaamayaasha iyo sababo

Dhibciyo Skulachev "Vizomitin" magacaabay syndrome ee "isha qalalan", isbedel da'da la xiriira ee qanjirka lacrimal, computer syndrome. Iyada oo ku saleysan xaqiiqda ah in cilmi baadhis lagu sameeyo saamaynta daroogada wali waa ay socdaan, waxaa kaloo lagula talinayaa cataract, glaucoma iyo daaweynta adag oo loo cudur kasta ee indhaha.

Sida Skulachev Vladimir tilmaamay, dhibco lagu shubo indhaha yihiin in ay dhacdo diidmo in daroogada, iyo sidoo kale carruurta da'doodu ka yar tahay 18 sano.

Codsiga uurka iyo inta lagu jiro naas-nuujinta

Si aad u taariikhda, full-nasiibin, indha la ', waxbarashada gacanta ku daroogada ee haweenka uurka leh, iyo sidoo kale la fuliyay in hooyooyin carruurtaada nuujiya. In view of xaalad this, waxaa laguma talinayo isticmaalka daroogada inta lagu guda jiro uurka. Haddii ay jirto baahi adag ballanta in muddo nuujinta ah, naas-nuujinta waa in la joojiyo.

Habka codsiga iyo qiyaasta

Daawada waa in la Ruhbaaniyad 1-2 dhibcood galay koleyga ee conjunctival ee isha qofka bukaanka ah saddex jeer maalintii. Iyadoo ku xiran darnaanta calaamadaha iyo darnaanta muddada koorsada daweynta cudurka lagu hagaajin karo shaqsi ahaan daaweynta indhaha.

Dhibaatooyinka ay keento iyo badinta

Sida laga soo xigtay cilmi, iyo sidoo kale baaritaanka caafimaad oo iyo shaybaarka ee daroogada, waxyeelo loo aqoonsaday, laakiin waxaa laga yaabaa muujin ka timid dareen diidmo oo xasaasiyadeed. badinta Data by codsiga la mariyo ee daroogada ee la heli karo.

isdhexgalka Drug

Data for isdhexgalka daroogada daawooyin kale leeyihiin kooxaha. Haddii ay jirto baahi ah ee codsiga wadajira "Vizomitina" la dhibicyo kale ee indhaha, indhaha farqiga ku keento ka dhexeeya waa in ugu yaraan 5 daqiiqo.

ganaaxyada

In tijaabo natiijada daroogada la helay, in "Vizomitin" keeni karaa rabshooyin hoy muddo gaaban, waxaana ku xiga ay hoos. Haddii ka dib markii maamulka ee daroogada ayaa lagu arkay rabshooyin muuqaalka, waa in ay ka fogaadaan gaariga ama farsamooyinka gacanta, iyo sidoo kale fulinta hawlaha u baahan in fiiro gaar ah, ilaa dib u soo kabashada ka buuxa toosan muuqaal ah.

Form sii daayo

Indhaha lagu dhibciyo la content firfircoon ee 0,155 ug / ml waxaa soo saaray dhalooyin gaarka ah ee polyetylen 5 mugga ml la Itlay - droppers iyo xir daboolka. Daawada waxaa la sii daayay oo keliya by qoro. Ka dhig dhibicda isha waxaa loo baahan yahay heerkulka a of 2 ilaa 8 ⁰ C.

Halkee si ay u iibsadaan daawada

Buy Dhibcood "Vizomitin" kuwaas oo qiimaha maanta ma aha weyn, haddii aad u la xidhiidhaan saamaynta la filayay, waxaa suurtagal ah in ku dhowaad farmashiye kasta Russia. celceliska kharashka ee dhibco Federation Ruush wuxuu ku saabsan yahay 500 rubles. Saamaynta daroogada si fudud oo waaaweyn. Tiro badan oo dadka ay awoodaan in ay nadiifiso iyo aragti cad iyada oo taasi ka dhigan tahay. Sida tilmaamay by Professor Skulachev, dhibco lagu shubo indhaha, qiimaha oo waxaa laga heli karaa qof kasta yeelan doonaa saamayn wax ku ool ah daweynta waa kuwa ay dhibaatadu ka cudurada indhaha.

Shaki kuma jiro in muddo waqti go'an ka dib, jaamacadaha cilmi qalin-waxbarasho-buuxa ah isha lagu dhibciyo "Vizomitin" ka dibna la itimaalka sare waxaa jiri doona fursado cusub oo loogu talagalay isticmaalka antioksidanter mitochondrial ma aha oo kaliya ku dhaqanka caafimaad ee indhaha, laakiin sidoo kale in laamaha kale ee daawada.

Reviews of diyaarinta

Kurtumm badan oo ka mid ah dadka loo isticmaalo indhaha lagu dhibciyo "Vizomitin" ku salaysan ay tallaabo. Bukaan-socodka ku faraxsanahay in diyaarinta uma baahna ku keento ka soo noqnoqda, oo la isticmaalo daba dheeraaday, oo aan inta jeer ee ay la isticmaalo ee lagu yarayn karo in hal mar maalintii. Sida ay macaamiisha, dhibaatooyinka indhaha runtii lagu xallin. Waxay joojiyaan in ay ceebna, daal yar, barar qaadataa meel. waxyeelo kasta, bukaan ayaa la ma dareentay.