Vitrification of oocytes: waa maxay?

Sanadihii la soo dhaafay, in unugyada labka iyo dheddiga giisa waxaa si dhakhso ah soo koraya. Hanaankani wuxu mar dambe loo arkaa in ay wax cajiib ah oo geli karin in ay dadka caadiga ah. IVF waxaa lagu fuliyaa dunida oo dhan. laboratories khaas ah iyo rugaha caafimaadka waxaa laga heli karaa in magaalo kasta oo waaweyn. Sanad kasta si ay u horumariyaan, habab hagaagtay cusub in bacriminta. Iyada horumarinta habkan, lamaane badan dhalays ay awoodaan in ay waalidiintu u noqdaan. Inta badan ururinta macluumaadka ku saabsan IVF, haweenka fool ah sida vitrification of oocytes. Ereygan waxaa loola jeedaa nidaam cusub kuu ogolaanaya inaad si loo hagaajiyo tayada ukunta.

Fikradda ah "vitrification uusayt" - waa maxay?

Si aad u fahamto sida habka of vitrification, waa in aad haysataa fikrad ah giisa unugyada labka iyo dheddiga. Howshaan waxay ku lug leedahay sampling unugyada jeermiga dumar ah (oocytes) ka ugxan. Markaas waxaa waa daahirintiisa iyo dheddiga deeq manida ama lamaanahaaga (haddii ninku ma carruur yeelan karin). Taas ka dib, saygoot share lagu meeleeyo saabka minka. Vitrification of oocytes - hab la mid ah cryopreservation ee oocytes. Si kastaba ha ahaatee, waa ka sii horumarsan. Under vitrification loogu tala galay lagu keydsho ee weli qaan gaadhin unugyada jeermiga. Sidaas darteed, oocytes la kaydin karaa muddo dheer. In kasta oo gobolka "qaboojiyay", unugyada Vitrified sii macne. Habkani waxaa loo arkaa in ay xal weyn ee daawada, maxaa yeelay, haweenka, iyada oo mahad naqa ay awoodaan in ay ilmo, xitaa ay ka maqan yihiin xubnaha taranka.

Waa maxay ujeedada vitrification uusayt waxaa lagu fuliyaa?

In Europe, fikradaha sida cryopreservation, vitrification of uurjiifka iyo oocytes, ayaa la ogaaday muddo dheer. Tani waxaa laga arki karaa on filimka galbeedka on daawada. In dalalka Midowgii Soofiyeeti ee hore, sidoo kale, dhakhaatiir aqoon u leh, kuwaas oo marka la eego muddo tobannaan sano. Si kastaba ha ahaatee, nidaamka, kuwaas oo la heli karo bukaanada dhawaan. Xaaladaha intooda badan, vitrification of oocytes soo giisa unugyada labka iyo dheddiga. Inta lagu guda jiro lagu keydsho ee unugyada qaan sidan oo kale qof dumar ah oo uu leeyahay fursad weyn oo IVF guul. Dufcaddii ugu horeysey ee oocytes soo xulay ka ugxan ma degi karo. In this dib-u-sampling mid ah waxyaabaha la looma baahna, maadaama ay jiraan unugyada horay Vitrified. Intaa waxaa dheer, waxaa jira xaalado marka labo ka mid ah oo Nadiif ah ku weydiiyo ilaalinta ee oocytes muddo dheer. waxaa inta badan loo baahan yahay in xaaladaha kala duwan bahal ah, taas oo qof dumar ah oo aan carruur yeelan karin. Sidoo kale, waxa la weydiisto noocan oo kale ah bukaannada u gudbinno diyaarinta qaliin si loo soo saaro xubnaha taranka.

Under heley ma ku talinaynaa ukunta vitrification?

Vitrification of oocytes iyo uurjiifka - hab bixisay heli kara qof kasta. muujinaya gaarka ah ee aysan u leeyihiin, hase ahaatee, waxaa lagama maarmaan ah oo kaliya xaalado gaar ah. Tani macnaheedu ma aha in haweenka qaarkood ma awoodi karaan vitrified unugyadooda. Si kastaba ha ahaatee, in maqnaanshaha sababaha lagu keydsho of oocytes ee fashion ka mid ah bukaannada ku talinaynaa cryopreservation. Inta badan vitrification la fuliyaa ka yar shuruudaha soo socda:

1. Diyaarinta si ovariectomy. Howlgalkan waxuu waa la fuliyay in kansarka ugxansiduhu iyo tuhun ee ay horumarka. Sababta Tani ma aha mid aad u baahsan, tan iyo xaaladaha inta ugu badan, heley kansarka dumarka laga saaro iyo ilmo-galeenka.
2. Awoodid la'aan in la helo shahwad qaato maalin ah oocytes. Sababtan awgeed, unugyada baahan yihiin in la xayiray ilaa iyo inta aan loo ogolaan doonaa wax for unugyada labka iyo dheddiga.
3. Kansarka deegaamaynta kasta. Meel kasta oo uu leeyahay kansarka ah waxay u baahan tahay kiimikada (cytostatic) daroogada radiotherapy iyo daaweynta. Mid kasta oo ka mid ah hababka loo baahnayn saamaynta uurka. Ka dib markii daawaynta waxaa baabbi'in kansarka ma aha oo kaliya, laakiin sidoo kale unugyada caafimaadka qaba, oo ay ku jiraan oocytes.
4. Haweenay ka doonayaa in ay carruurta in muddo fog, tusaale ahaan, ka dib dhalmo-dayska. Xaaladaha noocaas dhif cryopreservation waa wax soo saar leh, maxaa yeelay, ukunta baraf leh habkan macne muddo dheer. Sidaa darteed, dhakhaatiir soo jeedin hab ka duwan - vitrification of oocytes.
5. IVF soo noqnoqda, haddii markii ugu horeysay ukunta aan la caadaysteen. Xaaladdan oo kale, oo bixiya vitrification in aan qaato wax ka saddex jeer.

deeq oocytes Vitrified - waa maxay?

Xaaladaha qaarkood, uumi ah oo Nadiif ah aysan awoodin in ay ku uuraysato ilmo, xitaa ayadoo caawinaad ka mid ah giisa unugyada labka iyo dheddiga. Waxaan ka hadleynaa haweenka la function oo yaraada ee gonads ah. Ujeedada this, bangiyada deeq oocytes lagu soosaaray. Nasiib darro, ma ay joogaan laga helo dalalka oo dhan. Dhamaan unugyada jeermiga qaan gaadhin yihiin xaalad vitrified, oo sidaas daraaddeed iyagu waa la kaydin karaa. Tilmaamayaasha for IVF isticmaalaya oocytes deeq kala yihiin:

1. cudurada hiddo go'aamisay - ugxansiduhu failure syndrome.
2. Maqnaanshaha oocytes ay sabab u tahay sifooyinka da'da nidaamka taranka ah (40 sanno iyo ka weyn).
3. Awoodid la'aan in la kiciyo ugxan sabab u ah waxqabadyada qalliinka ee ugxan, gaadhista chemotherapy ah.
4. Halista ilmaha qaba cudur hidde.
5. Soo noqnoqda IVF, ayaa iminka natiijooyin oo sabab u ah "tayo liita" ukunta iyaga u gaar ah.

Yaa noqon kara oocytes deeq vitrified ah: Shuruudaha

Qorsheynta Qoyska - taasi waa go'aan aad u xun, gaar ahaan xaaladaha marka lamaanaha waxaa lagu qasbay in ay isticmaalaan unugyada deeq. Ka hor inta aadan ka heli oocytes iyo iyaga hoos vitrification, dhakhtarka fuliyeen sahan badan oo ka mid ah labada qof dumar ah oo wax la siiyo. Mid ka mid ah xaaladaha ku xoogeeyey bangiga of ridani la qaboojiyey, waa magaciisa. In uu yahay, waalidku ma oga saabsan deeq, iyo qeybsanaan. Shuruudaha dumarka doorta oocytes ay vitrified:

1. Age: 20-35 sano.
2. la'aanta ah ee cudurada jir iyo hidaha.
3. Aayar loogu dhawaaqaa phenotype.
4. Joogitaanka deeq ugu yaraan hal cunug ka mid ah iyaga u gaar ah.
5. Raali ka gaarka ah.

Farsamo ee vitrification

Inta aanad bilaabin si ay u hakiso gametes dumar ah, lagu qabtay kicinta ugxan. Waxaa lagama maarmaan ah in oocytes waxay ahaayeen dhowr ah, halkii ay ka mid. fulan caadi ah ka dib markii uu dhacaa inta lagu guda jiro ugxan iyo follicle dhalidda ee ugxanta mid keliya. Kicinta la sameeyaa daawo. Next waxaa la sameeyaa ultrasound ah miskaha. Haddii aad ka heli ugxan oo uu soo ogaaday iyo oocytes ee ugxan in tiro ku filan, nidaamka IVF la sii. goosashada gacanta waxaa lagu fuliyaa ka yar suuxinta guud. Si dillacinin irbad halkaas ku dhuftay, halkaas oo oocytes ah, nidaamka oo dhan la sameeyaa iyada oo ay hoggaaminayaan ultrasound. Ka dib markii qaadashada wax ka si ay u bilaabaan marxaladda soo socota - ilaalinta ee oocytes qaan gaadhin. Vitrification of oocytes waxaa lagu qabtaa wareegga dabiiciga ah ay sabab u tahay habka lagu keydsho degdeg ah. Tani waa feature ugu muhiimsan ee habka ilaalinta this.

Faa'iidooyinka vitrification of oocytes

Marka la eego in vitrikatsii habka bilaabeen inay si tartiib tartiib ah u bedelo hababka kale ee ilaalinta ee ridani iyo uurjiifka, waxaa quman ma aha oo kaliya in ay dhakhaatiirta laakiin sidoo kale bukaanka. Habkani waxa uu leeyahay faa'iidooyinka soo socda:

1. Suurtagalnimada in dib loo dhigo uurka. Sababo la xaqiiqada ah in oocytes iyo uurjiifka waa la xayiray muddo dheer (ku xiran tahay go'aanka qof dumar ah).
2. Awoodda in ay dib nidaamka IVF aan qaato wax ka ee jeer labaad (ama ka badan).
3. Awoodda in ay ku uuraysato qaliin taranka qanjidhada, shucaaca ama kiimiko ka dib.

Maxay ahayd farqiga u dhexeeya vitrification iyo cryopreservation of ukunta?

Sida la og yahay, habka kriokenservatsii iyo vitrification of oocytes waa mid aad la mid ah. Labada hababka waxaa loogu talagalay baraf ah oocytes iyo uurjiifka si ay u ilaaliyaan oo ay meelmar ah. Si kastaba ha ahaatee, waxaa jira kala duwanaan qaar ka mid ah. Inta badan, cryopreservation uusayt qaan burburay. Tan waxa u sabab xaqiiqada ah in habkan ku lug leedahay wax lagu keydsho gaabis ah. Sidaas darteed, cytoplasm dareeraha beddelay kiristaalo baraf. Si ay u dhaawici derbiga unug. Habka u fiican ee cryopreservation of oocytes waa vitrification. Dhalaali boqolkiiba marka fulinta ay aad uga hooseeya, sida qaboojinta ee ukunta dhacdaa dhow goobtii. Taasi waa farqiga ugu weyn ee ka cryopreservation waxaa loo tixgeliyaa technology cusub si ay u ilaaliyaan oocytes dheer ee gobolka laysku halayn karo. Si aad u dhigto fikrad muddo dheer habka kaliya ee vitrification. Cryopreservation ma bixiso natiijo waarta sida.

Sidee IVF ka dib markii vitrification of oocytes?

vitrification uusayt waa la fuliyay meel kasta. Hakinta of gametes iyo uurjiifka muddo dheer ku hawlan kaliya in laboratories takhasus sare leh. Ku dhawaad rugta kasta oo qalab this leedahay bangiga of oocytes deeq vitrified. Marka qof dumar ah oo uu go'aansaday in uu jeclaan lahaa in ay ku uuraysato ilmo, unugyada waxaa la diiriyay. Markaas isticmaalaan farsamada ICSI la sameeyaa unugyada labka iyo dheddiga. embriyaha The keentay waa la hoos geliyey culturing (3-5 maalmood) oo nimo galay oo siiban diyaarsan. Unugyada haray in la bacrimiyey karaa mar vitrified. Marka isku day ah in galaha nidaamka IVF lagu celceliyo.

Vitrification of oocytes: dib u eegista ee dhakhtarrada

Currently, vitrification iyo kaydinta of oocytes iyo uurjiifka waxaa lagu qabtaa dhammaan magaalooyinka waaweyn ee daawada horumariyo. Marka habkan la baaro oo uu laftiisa cadeeyay, dhakhaatiirta hadlo waxa ku saabsan si wanaagsan, isagoo mahadiyay faa'iidooyinka ay ka gaareen kale (hore) kaydinta ukunta nidaamka. Awoodin inay hakiso oocytes iyaga u gaar ah ay yihiin haween badan. Nidaamka kharash ah oo ku saabsan 12 kun rubles. Qiimaha waxaa loogu talagalay vitrification. Qiimaha lagu kaydiyo oo ka mid ah unugyada qaboojiyay waa 1000 rubles bishiiba.