Daawada "Captopril" waxa? Codsiga, dib u eegista, qiimaha

Waa maxay daawada "Captopril", kaas oo loo isticmaalo iyo waxa guryaha? Jawaabaha su'aalaha oo dhan waxaa laga heli karaa qalabka of this article. Intaa waxaa dheer, waxaan kuu sheegi doonaa ah oo ku saabsan sida loo qaato daawooyinka iyo waxa ay waxyeelo iyo sababo isticmaalka waxa ay leedahay.

macluumaad guud oo ku saabsan wax soo saarka ee daawooyinka

Drug "Captopril" ee Latin u muuqataa sidii "Captopril". daroogada Tani waa inhibitor a dardaro ee enzyme angiotensin-diinta (ACE ama soo gaabiyo). Waxa uu si weyn loo isticmaalaa in ku dhaqanka caafimaad, in ay si degdeg ah loo yareeyo cadaadiska dhiigga.

The Halabuurka iyo qaab daayo daroogada

Medicament "captopril" - ka oo qalab loo xilsaaro? Caadi ahaan, dhakhaatiirta u qori kuwa si joogto ah dhibaato ka soo hypertension. daroogada soo bandhigay waxaa lagu iibiyaa oo kaliya ee foomka of kiniin qasabad yar in waxaa la geeyaa kartoonka. Walaxda firfircoon ee daroogada tani waa captopril. Its content ku jirta kiniin kasta waa 25 ama 50 mg. Mid ka mid ah xirmo waxaa laga yaabaa in 100, 50, 40, 30, 20 ama 10 gogo '.

tallaabada pharmacological daroogada

Sida kor looga hadlay, kiniin "Captopril" barashada kaas oo la nested in kartoonka, waa inhibitor ah enzyme angiotensin-diinta (ACE i.e.).

Waa in la ogaadaa in guryaha antihypertensive ee daroogada la xidhiidha Iscelin tartan rasmi ah ee hawlaha ACE, taasoo keentay in qaab beddelidda weyn heerka hoos u of angiotensin 1 ilaa 2 angiotensin, taas oo qayb ka vasoconstrictive si caddaalad ah awood.

Ka dib markii hoos u dhac weyn oo fiirsashada of angiotensin 2 waa koror joogto ah hawlaha renin plasma by bi'inaya -celin xun marka la sii daayay, iyo hoos u si toos ah wax soo saarka aldosterone. Intaa waxaa dheer, medicament ah "Captopril", analogs kuwaas oo halkan lagu soo bandhigay, saamayn ku yeelan karaan habka kallikrein-kinin ah, oon ku hortagga burburka ee bradykinin.

Sababo la xiriira saamaynta vasodilating ee daroogada ah si weyn u yaraynaysaa guud ee iska caabin ah vascular (durugsan), cadaadis waslad gaddoonka ah iyo iska caabin vascular pulmonary iyaga oo ku. Intaa waxaa dheer, waa inay awoodaan in la kordhiyo mugga daqiiqadii muruqyada wadnaha iyo jimicsi dulqaad.

Haddii daroogada "Captopril" ka, dib u eegista ah kuwaas oo wanaagsan, qaado waqti aad u dheer, waxa ay ka hortagtaa horumarinta wadnaha oo shaqadiisa gaba, yaraynaysaa darnaanta hypertrophy myocardial of ventricle bidix, iyo sidoo kale hoos horumarka ee ilmogaleenka.

Intaa waxaa dheer, medicament waa inay awoodaan si looga hortago horumarka ee nephropathy diabetic, hoos efferent midab arterioles kelyaha, iyo glomeruli weyn u hagaajin hemodynamics intraglomerular.

Pharmacokinetics daroogada

Ka dib markii qaadashada daroogada uu si deg deg ah gudaha u nuugo. Xeerka medicament a bilaabmaa ku saabsan 40-60 daqiiqo ka dib. fiirsashada ugu badan waxaa lagu gaarayaa in jidhka bini'aadamka ka dib saacad ugu horeysay.

Waa in la ogaadaa in qaadashada isku mar oo cunto ah la daroogada oo ay jidhkiisa yaraynaysaa ay absorbability of 30-40%. Tani waa sababta kiniin waxaa lagula talinayaa in ay qaataan ka badan 1 saac cuntada ka hor ama ka dib 1-1.5 saacadood intaas ka dib.

Duration garoomada isticmaalka medicament ah (si ay u hoos u cadaadiska dhiigga) ka dib waxay ku xiran tahay badnaanta ee ay soo dhaweynta iyo qiyaasta. Waayo, horumarinta saamayn buuxda ku-daweynta bukaan-socodka ah waxaa laga yaabaa in u baahan yihiin dhowr toddobaad ah therapy.

Astaamaha iyo sifooyinka "Captopril" daroogada

Haddaba aad u ogaato in uu yahay daroogada "Captopril", kaas oo loo isticmaalo iyo sida ay u dhaqmaan marka loo eego jidhka bini'aadamka. Laakiin si ay u fahmaan sababta daroogada tani waa sidaas oo caan ah, waa inaad tixgelisaa hantida.

walaxda firfircoon taas oo ah qayb ka mid ah "Captopril" diyaarinta leeyahay vasodilating, antihypertensive iyo guryaha cardioprotective.

daroogada Tani waa awood sii kordhaysa sii daayo walxaha bayoloji firfircoon in ay leeyihiin saamayn natriuretic. Sababo la xiriira hantida this si weyn hagaajinaysaa socodka dhiigga kelyaha. Intaa waxaa dheer, medicament "Captopril" ee cadaadiska iyo yaraynaysaa guud post-loader on wadnaha, iyo kordhinta wax soo saarka wadnaha.

Tilmaamayaasha ay u isticmaalaan daroogada

daawo bandhigay tilmaamay lagu daaweyn jiray oo ka mid ah cilladaha soo socda:

• hypertension halbowle iyo renovascular. Waxaa loo isticmaali karaa in isku darka ama sida monotherapy.
• Xanuunka of ventricle bidix. Sida caadiga ah, daroogada waxaa loo isticmaalaa ka dhanka ah dadka qaadday wadno oo hadda ku sugan xaalad caafimaad ahaan xasilloon.
• nephropathy Diabetic. Xilsaaray kaliya kuwa uu leeyahay sonkorowga nooca ugu horeysay, sida dadka insulin-ku tiirsan.
• Cardiomyopathy.

Drug "captopril" - waxa kale oo loo xilsaaray dawadan? Sida la og yahay, daroogada loo soo bandhigi karo iyo sida loo isticmaalo ee therapy isku dhafan ee wadnaha (gabsiiya).

Sababo isticmaalka medicament ah

Sida laga soo xigtay tilmaamaha, daroogada "Captopril" waa mamnuuc in ay qaataan in arrimaha soo socda:

• In case of diidmo inay qayb firfircoon - captopril. Sidoo kale waa in la ogaadaa in daroogada firfircoon laguma talinayo yaa ugu Sugan kuwa diid ah ay jirto koox si cad daroogada, kuwaas oo inhibitors ee enzyme angiotensin-diinta (i.e., bukaanka horumariyo barar angionefrotichesky inta lagu jiro daaweynta inhibitor kale ACE).
• Marka muujiyay hawlgalka beerka aadanaha.
• In si lama filaan cardiogenic.
• Marka cudurada dheefshiidka mareenka.
• Marka muujiyay xaaladda shaqada kelyaha aadanaha ka dib markii xubin badalida biibiilaha, stenosis laba geesoodka ah ee halbowlayaasha, azotemia, hyperkalemia, iyo hyperaldosteronism hoose.
• Haddii hypotension.
• In cudurada difaaca.
• stenosis Mitral iyo stenosis aortic.

Intaa waxaa dheer, daroogada "Captopril" analogues daroogada this laguma talinayo haweenka uurka leh, carruurta ka yar 18 sano jirka ah, iyo sidoo kale hooyooyin carruurtaada nuujiya.

Drug "Captopril": waxbarida, qiimaha daawada

Sida laga soo xigtay tilmaamaha ku lifaaqan, daroogada waa in la qaato ilaa 1 saac cuntada ka hor. Muddada daaweynta iyo mudada qiyaasta daawada bandhigay waa in loo qeexaa dhakhtar oo kaliya shakhsiga ku saleysan, taas oo ku xidhan nooca iyo socodka cudurka jira.

Sidaas daraaddeed sida loo qaato daawada "Captopril"? Qiyaasta (hore) ee medicament ee cudurka of hypertension waa 12.5 mg laba jeer maalintii. In baahida ba'an ee hal mar waxaa loo isticmaali karaa soo diyaarinta ee 2 kiniin oo 25 mg. Laakiin haddii ay taasi soo dhaweynta waa la jecel yahay in la kala qaybiyey 3 jeer. Qiyaasta ugu badan ee maalin walba ah ee medicament noocan oo kale ah waa 150 mg.

Haddii dhakhtarkaagu uu kuu qoray daaweynta dayactirka muddo dheer, daawada "Captopril", kuwaas oo maragga aan kaliya kor u eegay, waa inay qaataan kaniiniga ugu horeeya (25 mg) saddex jeer ama laba jeer maalintii.

Marka hypertension renovascular iyo qiyaasta kelyaha hore ee medicament waa 6.25 mg saddex jeer maalintii. daryeel taageero ah waa in ka mid ah samaynta 1 kiniin ah (25 mg) saddex jeer maalintii.

Haddii aad cudurka wadnaha chronic oo ay jiraan khaladaad in kelyaha, qiyaasta hore waa in ay 12.5 ama 6.25 mg saddex jeer maalintii. Sayidka 2-3 toddobaad kasta waa in la keenay dose dayactirka ay of 25-50 mg, iyadoo inta jeer ee isku mid ah. muddo postinfarction habka aqbaliddoodii of medicament la mid ah.

Kooxda ACE daroogada ee dadka waayeelka ah ee loo xilsaaray kaliya aqoonyahanka. Xaaladdan oo kale, daaweynta waa in shakhsi ahaan. "Captopril" dadka aqbalay, kuwaas oo waa in ay qiyaasta ugu yar. Intaa waxaa dheer, waxaa laguma talinayo in la kordhiyo daawada oo dhan. Marka lagama maarmaan, in aad wixii intaa isticmaali kartaa durayo loop a.

Sida qiimaha, ka dibna 40 kiniin oo ah alaabta this waxaad yeelan doontaa in ay bixiyaan oo ku saabsan 50-60 rubles Ruush. Sida aad arki karto, waxay ka dhigan tahay "Captopril" waa daawo qaali ahayn in cadaadis dhiig oo wax ku ool ah ka hooseeya hab caafimaad.

Taken si taxadar leh u daran

daawo bandhigay waa in la qaato oo la taxaddar dheeraad ah marka:

• Iscelin oo dhuux laf ka mid ah wareegga dhiigga,
• shalalka daran;
• diabetes;
• ischemia cerebral ;
• cudurka wadnaha.

waxyeellooyin

Sida laga soo xigtay tilmaamaha, ka dib "Captopril" daroogada ee bukaanka socda reactions dhinaca dhici kara:

• bronchospasm, boronkiitada, neefta oo ku qabata, qufac qalalan xumeyn;
• Habdhiska niyad-jabka, madax-xanuun, suuxitaan, ataxia, dawakhaad, jiririco ee jirka sare iyo hoose, iyo sidoo kale dareen ah kabuubyo, wareer, rabshooyin ee urta iyo aragtida, daal, niyad-jabka,
• dermatitis exfoliative, cuncun, finan maqaarka ah, photodermatitis, pemphigus, anjioedema, urtikaria, shoog, necrolysis epidermal sun ah, alopecia;
• rabshooyin garaaca wadnaha, kog, hypotension orthostatic, Wadnaxanuun myocardial, tachycardia;
• khalkhal dhadhanka, yaaqyaaqsi, rabitaanka cuntada oo luma, stomatitis, lalabo, calool, glossitis, lesions kolit xabka gastric iyo afka, shuban, matag, xerostomia, calool xanuun,
• paresthesia, arthritis, neuropathy durugsan;
• neutropenia, hyperkalemia, Torombositobiiniya, Agranulocytosis, eosinophilia;
• oliguria, proteinuria, shaqada kelyaha daciif ah;
• hepatitis cholestatic, ganaca, cholestasis, galleeyda hepatocellular.

Sida laga soo xigtay jawaabaha in ka tago macaamiisha daroogada this, waxyeelo dhici kara waxyaabo kale oo badan, haddii, inta aad qaadanaysid daawada in ay u hoggaansamaan low-cusbo ama milix cunto-free.

Drug "Captopril": badinta

In xogta badinta ka dhigan tahay bukaanka muujin kartaa waxyeelo sida Wadnaxanuun myocardial, iyo ninba dhibic degdeg ah ee dhiig-karka, qas ba'an ee wareegga cerebral iyo dhibaatooyinka thromboembolic.

tallaabooyin taxaddar

Sida laga soo xigtay khubaro, waxaa laguma talinayo in ay qaataan daawada la diuretics potassium-uubatooyin xunxun, iyo daroogooyinka kale oo si weyn u kordhin fiirsashada of potassium ee plasma dhiigga. Haddii aan iska indha Council this, waxaa jira halis weyn oo hyperkalemia.

Intaa waxaa dheer, daroogada "Captopril" waa in la isticmaalaa si taxadir leh xad-dhaaf ah oo la soo dhaweynta isku mar ka dhigan tahay "Procainamide", "" allopurinol "," azathioprine "ama immunosuppressants kale, gaar ahaan cudurada of function kelyaha.

In cudurrada waajihi connective nudaha, iyo sidoo kale wadnaha chronic, daroogada baahan oo keliya in la qaado iyada oo ay kormeerayaan caafimaad dhow.

Sidoo kale waa in la ogaadaa in, sida ay bukaanada iyo dib u eegista caafimaadka, saamaynta hypotensive of medicament u yaraynaysaa daroogada "indomethacin" iyo estrogens.

xaaladaha kaydinta

Drug "Captopril" waxa loola jeedaa List daroogada B. daawo Tan waxaa lagu sii daayay silsilado farmashiyaha oo kaliya on warqad dhakhtar ee. Its nolosha shelf waa 3 sano laga bilaabo taariikhda la sameeyay. hab noocan oo kale ah ka kooban doorbidayaa in meesha mugdiga ah oo qalalan, heerkulka a aan ka badnayn 25 ° C.

analogues daroogada

Sida ay qayb firfircoon ayaa soo socda analogs dhismaha daroogada this:

• "Captopril Verein";
• "Angiopril-25";
• "Captopril Weyniga";
• "Alkadiene";
• "Captopril Sandoz";
• "Vero Captopril";
• "Captopril UBF";
• "Blokordil";
• "Captopril Akos";
• "Hexane Captopril";
• "Capoten";
• "Captopril FPÖ";
• "Captopril Sar";
• "Katopil";
• "Tegeyay Captopril";
• "Epsitron";
• "Captopril STI."

Sida aad ka arki, daawo gudbiyey ayaa garoomo dhowr ah gaar ah. Sidaa darteed, bukaanka inta badan kicisaa su'aasha ah waxa fiican - daroogada "Captopril" ama "Capoten". Farqiga maamulaha u dhaxeeya. Waxay ku kala duwan ka soo midba midka kale kaliya by saaraha. Sababtan awgeed, waxay ka dhigan tahay "Capoten" qiimihiisu yahay 3.5 jeer ka qaalisan daawada "Captopril".

Reviews of diyaarinta

Inkastoo qiimaha hooseeyo, medicament ah "Captopril" ku ool ah hoos u cadaadiska dhiigga. Bukaan-socodka kuwaas oo si joogta ah loo isticmaalo daroogada this sheegaya in saamaynta ay cad 1-3 saacadood ka dib qofku cuno gudahood.

cadaanyo Individual ka dib markii codsiga ah ee wakiilka ka dhaca ah oo ku saabsan 5-8% dadka. Dad badan oo ku doodaya in daroogada this sababa barar daran. Taasi waa sababta ka hor si ay u isticmaalaan, hubi inaad la tashato dhakhtarkaaga. Haddii habka "Captopril" waa kooxda ugu yaraan hal saamayn, waa la jecel yahay in ay diidaan ka oo tag on daawo loogu talogalay cadaadis dhiig oo sareeya ka koox kale.

Waxaa jira wax badan oo ka mid ah dib u eegista in daroogo "Captopril" "Capoten" iyo analogues kale ee lacagtaas wax ku ool ah ka caawisaa in laga takhaluso of hypertension dadka waayeelka ah. Laakiin ka hor inta farsamo noocan oo kale ah, hubi inaad la tashato dhakhtarkaaga. Intaa waxaa dheer, qofka gaboobay in la baabi'iyo cadaadis dhiig oo sarreeya iyo cudurrada kale waxaa lagu talinayaa in la isticmaalo oo kaliya qiyaasta ugu hooseeya ee daawo.

Ma ammaan si ay u isticmaalaan daroogada?

On ku salaysan isbitaalka gobolka ee Rivne (Ukraine) ee 2010, daraasad la sameeyay inta jeer ee waxyeelo ka qaadashada daroogada "Captopril". In habka this, ka soo qayb galay dadka qaba fudud iyo kuwa dhexdhexaadka hypertension halbowlaha. Sidaas darteed, oo ka mid ah 500 maadooyinka ka cawday waxyeelo dadka kaliya 73. Kuwaas oo kala ah, 53 - joojiyo qaadashada daawada, iyo 20 hartay - sii waday, sida ay ogaadeen in waxa ay keentaa badan oo dheeraad ah oo wanaagsan ka badan waxyeelo caafimaad.