Daawada "Prosulpin": diiwaanka, dib u eegista iyo analogues

Daawo "Prosulpin 'tilmaamaha loogu isticmaalo waa taagan yahay sida daroogada awood waallida dajiya oo loo isticmaalo in lagu daaweeyo cudurada kala duwan ee habka dareemayaasha jirka iyo cudurada kale. Faahfaahin dheeraad ah oo ku saabsan diyaarinta kor ku xusan, akhriso.

sharaxaad gaaban of diyaarinta

daroogada waxaa iska leh kooxda -benzenamine bedelay. Sidaas oo kale, waxaan dhihi karaa in ay tahay a daawada waallida dajiya caadiga ah "Prosulpin". khubaro Guest tilmaamay in ay tallaabo loogu talagalay xanibeen receptors dopamine (D2i D3). Sababo la xiriira daroogo la iibiyay waallida dajiya soo saartaa saamayn ku daweyn.

50 ama 200 mg ah hal kiniin waxa ku jira sulpiride "Prosulpin" diyaarinta.

Dhibaatooyinka ay keento marka la qaadanayo daawada, dabcan, ay dhacaan xaaladaha qaarkood. Sidaa darteed, bukaan inta lagu guda jiro therapy kor ku xusan ee waallida dajiya waa in ay ka yar kormeer caafimaad adag.

daawada waxa uu leeyahay noocyo dhowr ah. Waxaa laga heli karaa qaab kiniin oo ah qaab kaabsoosha, xal u ah maamulka muruqyada dhexdooda iyo hoorarka waayo qofku cuno.

Daawada waa in lagu kaydiyaa heerkulka qolka caadiga ah, laakiin ma ka badan tahay 25 darajo Celsius. Meeshu waa in si wanaagsan loo ilaaliyo iftiinka iyo qoyaan. Ku dhawaad laba sano oo nolosha shelf "Prosulpin" daroogada. Analogues ma aha adag tahay in la helo. Daawooyinka suuqa tiro balaadhan oo ah kursiga keydka ee daroogada kor ku xusan.

tallaabada pharmacological ee wakiilka la iibiyay daweynta

Daawo "Prosulpin" kuwaas oo photo waxaa hoos ku, waa wakiilka ah ee waallida dajiya waa neuroleptic ah. sulpiride walax ay sabab u xanibeen ee receptors dopamine ee gobolka tuberoinfudibulyarnoy kor u koror weyn oo heer prolactin. Waa in la ogaadaa in 60-80% heerka kala duwan ee kala duwan ka xanibeen receptors dopamine.

Arintaan kala duwan la mid ah ku filan sare si ay benzamide ah, taas oo caan ku feature a sida saamayn bifazicheskoe on nidaamka dopamine neurotransmitter sida. Intaa waxaa dheer, waxay xannibi kororka ee gobolka Avv dopamine synaptic, i.e. cadaawad receptor auto presynaptic D2 D3.

Waa in la ogaadaa in samaynta kor ku xusan si dhexdhexaad ah waa hawl neuroleptic. dambe waxaa weheliso timoanalepticheskim kale oo talaabo madadaalo of qalab ah.

daroogada ee kor ku xusan ayaa saamaynta pharmacological soo socda:

• antiemetics (Go'doominta receptor dopamine ayaa la sameeyaa keebka matag zone dhexda);
• niyad jabka,
• waallida dajiya.

Sulpiride muujinaysaa saameynta niyad jabka at qiyaasood oo ilaa 600 mg. Kor bixinta this ayaa hore u la arkay saamaynta waallida dajiya daroogada this on jidhka.

Intaa waxaa dheer, daroogada "Prosulpin" edbinta muujinaysaa waxay soo saartaa saamayn doorashada hypothalamus ah, calaamadaha boog gastric iyo gastroduodenitis. Sayidka cadaadiyeen xarumaha excitation sare ee habdhiska u dabacsanaadaan, hagaajinaysaa ququlka dhiiga ee u caloosha, badashada degdegsiimada unugyada granulation, habka of dheecaan xab ee caloosha, waxaa la aasaasay cusboonaadeen epithelium, badashada qalintaanka hagaajinaysaa unugyada.

Yaa waa inay qaataan dawo this?

Waa maxay daawada muujinaya "Prosulpin" loo isticmaalo? Ujeedooyinka-daweynta, daawooyinka ku xusan waxaa loo isticmaalaa in cudurada sida:

• cudurada maskaxda;
• boogaha stress ee marinka dheef shiidka,
• boogaha astaamaha;
• gastroduodenitis;
• caloosha boog;
• mindhicirka xanaaq (colon),
• boogaha daawo;
• ulcerös kolit nonspecific;
• Depression eray oo kala duwan;
• neuroses;
• niyad jab,
• disorder dysphoric;
• schizophrenia,
• chronic xanuunada maskaxda ;
• xanuunka dhanjafka,
• cudurka dhimirka ee daran;
• vertigo eray oo kala duwan (neuritis vestibular, yaridu vertebrobasilar, basilar, cudurka Meniere ee, otitis media).

Drug "Prosulpin" tilmaamaha loo isticmaalo bixisaa si aad u codsato daaweynta xanuunada dabeecadda iyo waalli in bukaanka dhallinyarada, carruurta ie. Tani jirrooyinka sida is-gudniinka, kacsanaan, ku qufulan. Sidoo kale daawo "Prosulpin" tilmaamaha loo isticmaalo insistently taliyaa si ay u isticmaalaan oo qayb ka ah koorsada ka mid ah therapy ee carruurta autism. Qalabkan waxaa loo isticmaalaa in lagu daweeyo bukaanada dhallinyarada da'doodu tahay 6 sano.

Sababo isticmaalka daawooyinka sheegnay

Drug "Prosulpin 'tilmaamaha loo isticmaalo laguma talinayo haddii bukaanka uu leeyahay calaamadaha cudurada soo socda:

• diidmo in daroogada;
• hyperprolactinemia;
• burooyinka prolaktinzavisimye (kansarka naasaha, prolactinoma pituitary);
• xanuunada niyadda;
• cabitaanka sumowga ba'an ay ku jiraan aalkolada,
• dabeecadaha gardarada ah,
• pheochromocytoma;
• sumowga Xiisad by daroogada ama daroogada kiniiniga hurdada;
• psychosis manic.

dalalka Kuwan oo dhammu waa sababo adag. Sidoo kale daawo "Prosulpin" tilmaamaha loo isticmaalo diidaya in la siiyo dumarka naas-nuujiyaan ilmahooga, carruurta da'doodu ka yar tahay 18 (200 kiniinka mg), bukaanka dhallinyarada ah ilaa 6 sano (50 kaniiniga mg).

Intaa waxaa dheer, waa in la xusuusto, sidoo kale waa loo baahnayn in la isticmaalo daroogada "Prosulpin" deficiency ee lagu dhasho ee lactose, glucose-galactose nuugeynin, lactose. Sababo isticmaalka wakiilada ku daweyn kor ku xusan ayaa sidoo kale codsan in haweenka uurka leh. u isticmaalaan bukaanka sida loo ogol yahay oo kaliya haddii faa'iidooyinka laga filayo daroogada noqon doonaa inta ka sareeya ka badan halista ka iman karta in ilmaha caloosha ku isaga ka.

waxyeellooyin

Marka la helo "Prosulpin" diyaarinta (manual muujinaysaa this), waxaad la kulmi karaan dhibaatooyin soo raaca qaar ka mid ah:

• on qayb ka mid ah habka hormoonada jidhka ah - galactorrhea, dysmenorrhea, amenorrhea, frigidity, kacsi la'aanta;
• ka dareemayaasha - suuxin, gariir, wareer, Tardive hore, extrapyramidal syndrome, somnolence, akinesia la hypertonicity muruqa ah, akathisia, excitation motor,
• kordhiyo waxqabadka of falgalka (ka dheefshiidka);
• anemia hemolytic, leukocytosis, anemia aplastic, granulocytosis, purpura, thrombocytopenic dhacaan qaadasho sare "Prosulpin" diyaarinta (by tallaabada ee dhiigga iyo habka dheecaanka ah);
• tachycardia, hypotension orthostatic, hoos ama kor u kacay cadaadiska dhiigga, hagaagay QT ah bareeg, mararka qaarkood horumarinta cudurada khatarta ah sida torsade des pointes syndrome (oo ka mid ah wadnaha iyo nidaamka).

Sidoo kale waxay keeni saamaynta kale dhinaca daroogada this. "Prosulpin" (jawaab Waano dhakhaatiirta iyo bukaanka jawaabaha ayaa u markhaati fura in this) Drug cadhaysiinina karaa ifafaale xun sida tardive dyskinesia, taas oo ah waxa lagu gartaa dhaqdhaqaaqa khasabka ah jiibta wajiga ama carrabka (la neuroleptics dheer daweynta dabcan dhammaan kooxaha), hyperthermia. Khubarada ka digay in ay dhacdo in ugu dambaysta si gaar ah muhiim in waqtiga si aad u joojiso habka kor ku xusan, tan iyo markii u kaca heerkulka noqon karaan wax caddaynaya cudurada khatarta ah sida sida neuroleptic syndrome malignant.

korodh miisaan, dhidid kordhay, finan maqaarka ah iyo cuncun - oo dhan oo ka mid ah waxyeelo sidoo kale waxay keeni kartaa daroogada "Prosulpin". Tilmaamaha, comments ka khubarada ku talinaynaa in kiisaska noocaas ah si ay u joojin qaadashada daawada kor lana dooni dhakhtar caafimaad oo degdeg ah gargaar iyo talo.

Isticmaal inta aad uurka leedahay kor wakiilka-daweynta

Teratogenicity daroogada ayaa laga helay iyadoo ay sabab u tijaabo xoolaha. Haweenka qaarkood kuwaas oo loo isticmaalo dawada inta aad uurka leedahay, oo waxba ma ay dhawraan saamaynta kor ku xusan. Laakiin bukaanka waxay heleen qiyaasta yar si adag loola jeedaa "Prosulpin". Tilmaamaha loogu isticmaalo, khubarada dhabta ah aadan haysan macluumaad gaar ah oo ku saabsan isticmaalka xaddi sare ee walax sida sulpiride. sidoo kale ma jiraan wax xog ah oo ku saabsan saamaynta dejinta la iibiyay ee horumarka ah ee maskaxda uurjiifka.

Taxadar ahaan khubaro ma talin in la isticmaalo dawadan loogu tala galay dumarka ee gobolka. In kasta oo mararka qaarkood, weli loo ogol yahay daaweyn jiray diyaarinta kor ku xusan ka mid ah bukaanka, ay ka filayaan ilmaha, laakiin si adag in qaadasho yar.

Khubarada la soco in haddii hooyada la siiyo neuroleptics muddo therapy sii dheeraaday, ee jajabka ka dhasha dhibaato la shaqo mareenka dheefshiidka (eg dibiro).

Haddii qof dumar ah oo daroogada u isticmaala inta lagu jiro muddada ka hor dhalmada, gacanta ka badan jidhkeeda iyo horumarka ilmaha caloosha ku takhtar waa waajib.

Waa in la xusuusnaado in galaa caanaha naaska daroogada "Prosulpin". Tilmaamaha loogu isticmaalo, khubarada dhabta ah ma ku talinaynaa waxaa qaadashada inta lagu jiro nuujinta.

Sida loo qaato daawada "Prosulpin"?

Guide bixiyaa bukaanka u isticmaali waallida dajiya ee kor ku xusan 8 saac oo kasta hal kiniin ah. Laguma talinayo inay daawada qaataan ka dib 16.00, sida ay hawl aad u waa kordhiyaa waqtigan. Waa in la ogaadaa in loo isticmaalo iyadoo aan loo eegin hadhuudhka ah oo soo maydhay hoos xaddiga ku filan ee diyaarinta ah dareere "Prosulpin".

Kiniiniyada ka kooban 200 mg ah sulpiride, waxaa aqbalay at calaamadaha daran ee schizophrenia, psychosis delirious iyo murugada. daroogada waxaa lagu qaadan karaa qaabab kala. Its dose maalin walba ugu badnaan 100 mg, ama ku saabsan 5 kaniiniga.

Kiniiniga, taas oo ka mid ah 50 mg ah sulpiride, waxay bixisaa tacliin qaataan, haddii bukaanka uu leeyahay calaamadaha neurosis, walwalka. 4 toddobaad gudahood, bukaanka waa in cunin ugu yaraan mid ka mid ah oo ugu badnaan 3 kaniini maalintii.

Sidoo kale, kaniiniyada, kuwaas oo la qaadi karo ee carruurta qabta dhibaatooyinka dabeecadda daran. da'da bukaanka sida waa in had iyo jeer ka badan tahay 6 sano jir. Qiyaasta ugu badan ee maalin walba dadka bukaanka ah in this category waa 5 ilaa 10 mg halkii miisaanka jidhka 10 kg.

badinta

Buugga muujinaysaa in macluumaadka sulpiride badinta waa xaddidan. Calaamadaha soo socda la arkay waxaa laga yaabaa in xaaladda this in bukaan:

• protrusion carrabkayga ku qabowjiyo,
• Tardive la surkoo spasmodic;
• aragti cawlan,
• afka oo qalala,
• horumarinta suurto galka ah ee NSAs;
• calaamadaha extrapyramidal;
• dhidid u korodho,
• lalabo,
• suuxin,
• gynecomastia;
• cudurka Parkinson,
• kordhiyo cadaadiska dhiigga.

Daaweynta gobolka ee kor ku xusan ka mid ah bukaanka waxaa lagu fuliyaa sida soo socota:

• maydhay caloosha bukaanka;
• magacaabay carbon ka shaqeysiin;
• therapy nidaamsan.

Haddii loo baahdo, xaaladaha daran, dhakhtarka kuu qori karaa khalkhalgelinta oo dheeraad ah, sida diuresis xal galiyey of hawlaha jidhka muhiim alkali ama socodka.

Waa in la ogaadaa in diyaarinta this qayib qayb ahaan in kelyaha.

qaybaha qaar ka mid ah bukaanka waa in ay qaadaan tallaabooyinka gaarka ah marka la isticmaalayo "Prosulpin" daroogada. Tani waxay khusaysaa ugu horayn in haweenka la caadada joogto ahayn, bukaanka qaba hypotension daran iyo dhiig-karka.

Waxaa kaloo muhiim ah in bukaanka qaba ee elektarooniga ah hordhaca qalalka iyo baaritaan caafimaad. Waa in la xusuusnaado in daroogada "Prosulpin" hoos baxayay marinkii hawl qabashada.

Intaas waxaa sii dheer, marka gaadiidka wadista u baahan yahay daryeel gaar ah inta lagu guda jiro daawaynta daawooyinka ku xusan. Waxaa kaloo muhiim ah in la xaddido hawlaha u baahan in dareen diidmo psychomotor degdeg ah iyo ka-fiirsashada sare.

Dhexgalka wakiilada kale ee daweynta

Tilmaamaha ma yihiin si adag ku talinaysaa in daawada kor ku xusan ee therapy isku dhafan leh levodopa. Labada Walxaha firfircooni waa ku Doodeen. Haddii bukaanka ah, kuwaas oo la ildaran cudurka Parkinson, qaadataa levodopa, dhakhtarka waa wakiilka waa in la soo xulay in uu leeyahay a saamaynta extrapyramidal yar.

Garaaca sida torsades de pointes uu sababi karo isku darka "Prosulpin" daroogada la:

• daroogada antiarrhythmic, oo ka tirsan fasalka IA (daawooyinka "Dizopiramid" "quinidine");
• daroogada "pimozide," "Haloperidol", "thioridazine" "Cisapride", "Pentamidine" murugada imipraminovymi;
• daroogada antiarrhythmic ku jira fasalka saddexaad (oo macnaheedu yahay "Sotalol", "Kakamiodaron");
• daawooyinka keeni calaamadaha cudurada sida bradycardia (beta-blockers, blockers calcium channel);
• daawooyinka in ay gacan muuqaalka kore ee calaamadaha hypokalemia (caloosha jilciya in ay yihiin stimulatory, diuretics hypokalemic, tetracosactide, glucocorticoids);
• Doodeen dopamine (antiparkinson): "apomorphine", "Amantadine" "Lisuride", "Ropinirole", "Entacapone" "Bromocriptine", "selegiline" "Pramipexole" "Piribedil");
• daawooyinka ee waallida dajiya in ay leeyihiin awood u leh inay keeni calaamadaha torsades de pointes ( "chlorpromazine" "Amisulpride," "Tsiamemazin" "pimozide," "Droperidol" "levomepromazina" "tiapride," "Sertindole" "Veraliprid" "Sulpiride") ;
• daawooyin ay ku jiraan lithium (dambaysta ah la taaban karo ay kordhayso khatarta cudurada extrapyramidal).

Sidoo kale, kiis kasta, daroogada "Prosulpin" waa in aan la lala isticmaalaa aalkolada. Last potentiates saamaynta ku dejinaysaa of neuroleptics.

Intaa waxaa dheer, haddii aan qaato daawada kor ku xusan isku dhafan oo bartamaha madadaalo walxaha (anti-xiiqda, anorectics), bukaanka waxaa laga yaabaa in ay la kulmaan astaamaha excitation xoog, isku yaacsanaan, welwel, welwel.

Waa in la xusuustaa in daawada waallida dajiya hoos heerka waxtarka ropinirole.

Keydka "Prosulpin" wakiilka-daweynta

Analogs ee waallida dajiya ee kor ku xusan:

• "Betamak T100";
• "Vero Sulpiride";
• "Betamax T50";
• "Depral";
• "Betamax";
• "Waxaydin ah";
• "Betamax T200";
• "Sulpiride";
• "Eglonil";
• "Sulpiril";
• "Eglek".

Laakiin bedelay oo aan wada tashi ka hor dhakhtarka uusan ku talinaynaa "Prosulpin" diiwaanka. analogues Its sidoo kale saamaynta ay kooxda shaqsi. Waxay keeni kartaa dhaawac weyn ku ah caafimaadka bukaanka.

Jawaabaha ee hab caafimaad "Prosulpin"

Reviews daawada kor ku xusan inta badan wanaagsan. Dad badan oo bukaanka u qaadanaya dalalka niyad. Waxay ku andacoodeen in qalab this ka caawisaa baabi'iyo calaamadaha cudurka waa ku dhowaad 100%.

Intaas waxaa sii dheer, bukaanno badan jawaabaha ku filan, taasoo in cudurada sida schizophrenia, enterocolitis, ulcerös, psychosis, enteritis, cudurka kolit, Irritable Bowel Syndrome, qaaday daroogada "Prosulpin". Reviews of tilmaamaya in kiisaska oo dhan, qalab ka soo saartaa saamayn bogsiinta cajiib ah. Intaa waxaa dheer, bukaan sheegaan in waxyeelo ka dhacaan aad u dhif ah.

daroogada kor ku leedahay dhibaato halis ah, sidaa daraadeed waxa uu isticmaali aan wada tashi ka hor la dhakhtarka gebi ahaanba la mamnuucay.