"Engerix" - Tallaalka hepatitis B ka kooban tallaalka, analogs iyo dib u eegis

"Engerix" - talaal lagu jiheeyo horumarinta hepatitis B. Sidaas darteed of adeegsigeeda saarta difaac wakiilka sababaya cudurka ka. Tallaalka - antigen a virus (dusha ugu muhiimsan), habka ugu dambeeyey ee nadiifinta, adsorbed on hydroxide aluminium. Tallaalka soo saaray fulinta technology DNA recombinant.

oggolyahay ee daroogada marka lagu maamulo dadka waaweyn, carruurta iyo dhallaanka halista ugu jira, celcelis ahaan 98%. Laga soo bilaabo maamul ee tallaalka la aasaasay by antibody HBs-gaar ah, kuwaas oo ka difaacan hepatitis B. coinfection "Engerix" hortagi kara hepatitis D.

Halabuurka The, foomka sii daayo "Engerix" daroogada

hab la heli karo ee kaabsulka. Qiyaasta in loo maamulo ilmaha u dhiganta 0.5 mL dadka waaweyn ah - 1 ml. Baakadaha waxaa ku jira ilaa boqol fijaan (toban, ama boqol iyo lixdan).

"Engerix" saare sidoo kale soo saartaa in fijaan oo in ka kooban 5 ml (oo u dhiganta 10 carruur qiyaasood) iyo 10 ml (oo u dhiganta 10 qaadasho ee dadka waaweyn) tallaalka. baakad The jira konton dhalo oo "Engerix".

Daawada waxaa loogu talagalay dadka waaweyn

Halabuurka The of 1 tallaalka ml ka mid ah antigen pathogene (20 micrograms) waxaa sidoo kale ka mid ahaa hydroxide aluminium. dejinta loo isticmaalo preservative haysta magaca "2-phenoxyethanol", waxaa jira raadad thimerosal, tan iyo markii la isticmaalayo walax this la macmalay medicament. Waxay la baabi'iyo thimerosal ka tallaalka, marka lagu nadiifiyo waa la fuliyay. In saaridda of gidrofosfatadigidrat daroogada loo isticmaalo, iyo digidrofosfatadigidrat sodium ah, biyo nadiif ah lagu daray.

Tallaal loogu talagalay carruurta

Si 1 ml of diyaarinta "Engerix" Halabuurka tallaalka sida soo socota:

• antigen pathogene (10 micrograms);
• lacagta ugu yar ee thimerosal walax;
• qaybaha dheeraad ah (la mid ah sida diyaarinta ah ee dadka waaweyn ah).

saamaynta pharmacological

antigen waxaa soo saaray iyada oo loo marayo dhaqanka Saccharomyces khamiir, waxa uu saamayn gaar ah. Saccharomyces soo saaray ay ka saareen unugyada ka antigen, habka ay u dhamaystiran nadiifiskeeda u heer-sare ah. Waxaa jira xog muujinaysa awood u leh inay "Engerix" si loo yareeyo suurtagalnimada of horumarinta hepatocellular carcinoma ay sabab u tahay maamulka tallaalka carruurta yaryar.

Tilmaamayaasha loo isticmaalo

tilmaamaha "Engerix" loo isticmaalo talinayaa in ka hortaga cagaarshowga B, kaas oo ka dhashay dhacdo ee fayraska. Tallaalka waxa lagula taliyaa kooxaha halista ku jira. Waxaa ka mid ah:

• kalkaaliyayaasha,
• dadka ku nool doonaa iyada oo xubnaha;
• dadka deggan gobollada-gud, waayo, hepatitis B,
• dadka ka cabanaya Khamriga,
• ardayda caafimaadka,
• bukaanka ayaa diyaar u ah inay fuliyaan hawlgallo ama hababka ogaanshaha invasive,
• fayras sidayaal kaas oo keena horumarinta hepatitis C,
• shaqaalaha saaraan diyaarinta immunobiological ka kooban qaybaha dhiig;
• caruurta agoonta, dugsiyada hoyga ah,
• shaqaalaha shaybaarka, sahaminta wax aadanaha;
• bukaanka waxaa lagu daaweeyaa by codsanaya irbadaha mukhaadaraadka;
• dadka ka cabanaya foomka chronic hepatitis C,
• Carruurta ku dhashay si ay haweenka ku jira sidayaal ah wakiilka sababaya hepatitis B;
• dadka loo aqoonsaday anemia sickle cell- ;
• kuwa xiriirka la leh dadka helay hepatitis B nooc kasta;
• Dadka halis sare u ah ee wax soo iibsaneyso hepatitis B ka dhaqan galmo oo bilaash ah;
• Dadka ku talajira in ay gobolka gud, waayo, hepatitis B tegin;
• dadka qaba cudurada beerka chronic socodka;
• bukaannada u baahan in dhiig lagu shubo, qalabka deeq dhiig dheefay.

Tallaalka hepatitis "Engerix" waxa lagu samayn karaa da 'kasta. Waxaa la sameeyey kuwa aan hore loo tallaalin, iyo kuwa ka tirsan tahay koox khatar ah.

sababo

Tallaalka waxaa lagu ma maamulo ee diidmo kaas oo lagu ogaan karo ka dib markii la isku duro hore ee daroogada. Joogitaanka cudurrada daran oo ba'an dhaca, geedi socodka faafa halis ah taas oo ay jirto qandho, - contra-muujinaya tallaalka.

In kasta oo xaqiiqda ah in caddaynta waxyeellada tallaalka si ay ilmaha caloosha ku, ka maqan inta lagu guda jiro haween iyo wallacaaga dhif tallaalo. Its fulinta waxaa badanaa laga sameeyaa oo keliya xaaladaha gaarka ah halkaas oo ay jiraan calaamado muujinaya qaar.

Isticmaalka tallaalka ah, qiyaasta

Maamulka muruqyada dhexdooda ku dhaqma ee qaybta bowdada anterolateral (carruurta yar yar, carruurta) ee muruqa deltoid. Waxaa laga yaabaa in maamulka subcutaneous, laakiin waxaa la fuliyay in Marar dhif ah, keliya marka bukaanka ku dhuftay nidaamka xinjirowga dhiigga. Grafting "Engerix" marnaba intravenously sameeyey. Sababta oo ah jaaniska yar ee jawaabta difaaca saarayso intradermal, subcutaneous iyo duridda galay badhida.

awoodda tallaalka isla markiiba ka hor la isku duro si fiican u ruxayso ilaa slurry a anfac badan waxaa si siman u qaybiyeen. diyaarinta Waa in aysan jirin Qurub shisheeye. Mararka ay dhacdo in qaab tallaalka ma u dhigma description this, hab this aan la isticmaalo tallaalka.

Haddii "Engerix" (tallaalka) waxaa loo isticmaalaa in weelka, in qabashada dose kasta loo baahan yahay in ay qaataan cirbad nadiif ah iyo silingaha. dhalada bilaabay kor loo isticmaali karaa ugu badnaan dhamaadka maalinta. Habkan wuxuu farayaa waafaqsan heerka dhigay by xeerarka antisepsis, asepsis.

qiyaasta

tallaalka Tallaalka nidaamka la go'aamiyo, taasoo la aqbalo ee dalka. Keeneysa in hab ka dhigay si waafaqsan da'da:

• ilaa 19 sano - 0.5 ml,
• 19 sano - 1 ml;
• daaweynta bukaannada ku jira cutubkan kelyaha ah, - 2 ml.

tallaalada carruurnimada ka hortag

Child tallaalo sameeyo dhalashada, hal bil iyo lix ka dib. Marka hirgelinta nidaamka noocan oo kale ah hore u bisha toddobaad nolosha difaaca ilmaha si pathogene ee hepatitis B. Haddii ay jirto baahi ah in la dardar-socodka this, duray soo socda waxaa la sameeyaa ka dib dhalashada bishii kowaad ee nolosha, ka dibna - in kii labaad. On bishii laba iyo tobnaad ee hirgelinta revaccination ayaa loo baahan yahay.

Haddii qof weyn ee carruurnimada aan la helin tallaalka ka dib marka ugu horeeysa ee kiiska labaad maalinta toddobaad, saddexaad - in kow iyo labaatanaad. Hal sano ka dib isticmaalka ugu horeysay ee daroogada la maamulo si joogta tallaalka.

Marka nidaamka kelyaha tallaalka hepatitis B 'Engerix "soo bandhigay barnaamijka: Maalinta eber - soddon - demoqaraadiyad. Si joogta ah u codsan daroogada lix bilood gudahood ka dib markii maamulka ugu horeysay. Bukaan-socodka noqonaya kooxda this, ka dhigi irbad la qaddar laba jibbaar ah (2 mg). Ka dib markii maamulka daroogada waxaa lagu talinayaa in ay sameeyaan baaritaan fuliyo (heerka caadiga ah waa in ay ahaataa aan ka yarayn 10 IU / l).

Dhallaanka la dhibaatooyin halis ah ee kelyaha maamulo 0.5 ml oo ah wax soo saarka, wax kasta oo ku haboon u hoggaansanaayeen talaalada wareeggeedii. Qiyaasta isku mid ah daroogada loo baahan yahay in ay dhalatay, kuwaas oo kelyaha sameeyo.

Haddii qof ayaa ay saameeyeen arrimaha sababtoo ah kaas oo dhici kara cudurka, codsan jadwalka tallaalka degdegsiimada. Marka ugu horeeysa ee lagu daro daawo, kuwaas oo ka kooban immunoglobulin ah. wakiilada noocan oo kale ah waxay leeyihiin saamayn xun ku hepatitis B. daroogada duritaanka buuga "Engerix" edbinta ku talinaysaa in aad samayn marka laga reebo irbado immunoglobulin ah (meelo kala duwan).

Haddii aad rabto in aad tallaasho dhashay oo hooyadiis - side of pathogene ama cudur xanuunsan hepatitis B, laga soo bilaabo bishii lixaad ee uurka, dhalmada ka dib of tallaalka maamulay isaga ugu qeybtii hore ee maalinta. tallaalka dheeraad ah waa la fuliyay hab ay dedijiyaan. Mararka qaarkood, in kiisaska noocaas ah waxaa lagu talinayaa in aad dalbato tallaalka si ay u taagoo immunoglobulin.

Ka dib markii marayay ninkii nidaamka oo dhan tallaalka revaccination hepatitis B muhiim ma aha. Ka dib markii dialysis iyo wax ka qabashada difaaca masaakiinta loo qaadan karaa qiyaasta sii xoojinta ah. sida loogu baahan yahay fulinta qeexay baaritaan fuliyo.

Dhibaatooyinka ay keento "Engerix"

Ka fikir falcelin xun ee jirka, horumarka ah taasoo keeni karta tallaalka 'Engerix ". tilmaamaha ku sifaysay waxyeelo sida, taas oo nidaamka muruqyada iyo dheefshiidka saameysey. Waxaa laga yaabaa in wax isdaba marin ku shaqaynaya nidaamka durugsan habdhiska, wadnaha, isbedel suurto gal ah in habka dhexe ee neerfayaasha. Ka dib markii la isku duro, waxa lagu ogaan karaa oo qaar ka mid dareen-celin alerji maxaliga ah.

jidhka bini'aadamka ka jawaabi karaan muujinta tallaalka ee calaamado u eg hargab, qidmeyntii, qandho, iyo khasaaro of xoogga. Xaaladaha qaarkood, horumarinta Torombositobiiniya, Lymphadenopathy, u muuqataa bronchoconstriction. Sida caadiga ah, dareen diidmo oo taban tallaalka way sahlan yihiin.

Kiisaska ah qiyaasta xad dhaafka ah ee tallaalka aan la soo dajiyey. Sidee inay wax ka qabtaan xaaladahan oo kale in horumarka calaamadaha aan loo baahnayn, ma ku xusan tilmaamaha.

Ka hor inta in ay isticmaalaan, si taxaddar leh baaris kooban oo la tasho dhakhtar.

isdhexgalka daroogada

"Engerix" (tallaalka) marka aad isticmaalayso immunoglobulins marka si looga hortago hepatitis B, ma yareeyo-baadh oo ka mid ah unugyada ay shardi tahay in maamulka daawooyinkan loo sameeyaa si gaar ah in kala duwan. Haddii kale, tilmaame ma noqon doonto kala duwan ee caadiga ah.

Waxaad isticmaali kartaa tallaalka ah oo ka hortagtaa horumarinta hepatitis B, oo ay la socdaan qalab kale oo noocan ah, oo waxaa lagu calaamadeeyay in jadwalka tallaalka iyo tallaalka sida qiyaas ka hortag ah oo ku saabsan tilmaamayaasha faafa. Waxaa muhiim ah in labada tallaal oo kala duwan waxaa maamula ee cirbadaha gaar ah laba dhibcood oo kala duwan.

Grafting "Engerix" waxay noqon kartaa heerka ugu dambeeya ee marinka ee tallaalka hepatitis B xaaladaha markii la bilaabay iyadoo la isticmaalayo tallaalada kale in ay leeyihiin saameyn la mid ah. Under xaaladaha isku mid ah, "Engerix" waxaa loo isticmaali karaa inta lagu guda jiro revaccination.

dhibaato ah u shaqeeyo tallaalka isku jira daawooyin kala duwan ah ayaa la arkay.

ganaaxyada

inta aad uurka leedahay

Fikrad ahaan, jaaniska waxyeelo ilmaha caloosha ku waa yar ay sabab u tahay hordhaca ah ee tallaalka. waxbarashada Clinical, taas oo caddayn lahaa saamaynta "Engerix" on jidhka, oo ay ku jiraan inta ay uurka aan la sameeyaa. "Engerix B" (la mid ah si la mid ah) ay yihiin waxtar u leh dumarka isku duro uur leedahay, keliya caddayn ku habboon dhakhtar aasaasay.

Features of daroogada

Muddada cudurku cagaarshowga nooca B waxaa lagu gartaa xaqiiqada ah in ay u socdaa badan, sidaas waxaa suuro gal ah cudurka qarsoon ee socodka waqtiga tallaalka. In bukaanka, kuwaas oo, ka hortaga cagaarshowga B waa wax aan macquul aheyn.

Sababtoo ah tallaalka ma hor istaagi karaan dhacdo ee cudurada, horumarka, taas oo gacan ka wareer kale. Tusaale ahaan, daawada waa xumaada haddii loo baahdo si looga fogaado horumarinta hepatitis A, C iyo E. Waxa kale oo aanu lahayn saamayn la doonayo on the wareer ah cudurada kale, taas oo beerka waxaa saameeya.

"Engerix" (tallaalka) ka dib hordhaca galay jidhka keentaa jawaab difaaca jirka, ay hadal ku xidhan tahay qodobo badan. Tusaale ahaan, wax ka qabashada difaaca nidaamka waxaa lagu go'aamiyaa galmada Aadanaha, isagoo da ', joogitaanka caadooyinka waxyeelada leh sida sigaarka, hab oo la soo saarin tallaalka. Inta badan, ka dib markii afartan sannadood, jawaabta nidaamka difaaca jirka ka yar fahmayaan badan dadka da'da yar. bukaanka noocan oo kale ah ku qaataan tallaal dheeraad ah sida loogu baahdo.

Haddii bukaanka uu cudurka HIV, dhibaatooyin kale oo difaaca jirka oo sabab u ah dialysis yaabaa in aanay awoodin in ay gaaraan-baadh oo antibody ku filan. Haddii koorsada ugu weyn uma oggolaan doono galo tarin, sida ay natiijada baadhitaankii u baahan karaan irbado dheeraad ah. Sababo la xiriira awood u leh inay keeni ficil-celintan jirka, taas oo ka duwan tallaalka jawaabaha 'Engerix' sheegay baahida loo qabo in ay haystaan qalab gaar ah in la baabi'iyo saamaynta noocan ah, inta lagu guda jiro maamulka daroogada. Xasaasiyad aad si deg deg ah u muuqan kartaa, sidaa darteed waa in aad noqon soddon daqiiqo si ay u dhawraan xaalad ka mid ah bukaanka oo la muday la sameeyey.

In jiritaanka cudurka yar ee u shaqeeyo tallaalay noqdo suurto gal ah markii uu heerkulka jirku caadi ugu soo noqonayso. barta at kaas oo la qorsheeyay in la soo bandhigo tallaalka, waa in la daaweeyaa wakiilada loogu talagalay therapy anti-filaan ah.

Tallaalka waxaa loo isticmaali karaa in ay dhacdo dhibaatooyinka beerka, ay si taxadar leh ay maamusho si ay dadka waayeelka ah.

analogues daroogada

In ka hortaga hepatitis B waxaa suurtagal ah in doorato tallaalka 'Engerix "ama" Regevak ". Analogs ah "Engerix 'The qalabka soo socda ayaa loo jecel yahay:" Euvaks "," Biovak ". Waxaa laga yaabaa in tallaalka "Eberbiovakom HB", "Shanvakom", "HB-Vaks." daroogada Habboon ee loo doortay dhakhtarka.

Reviews of "Engerix" hab

Haddii loo baahdo, ka dhigi tallaalka caadiga ah ka gees ah tallaalka cagaarshow B inta badan waa "Engerix" khusaysaa. Waalidku ma aragto waxyeellooyin gaar ah, waxay guud ahaan ku qanacsan yihiin natiijada yihiin. Currently, waxaa jira wax badan oo ka mid ah jawaab-celin wanaagsan oo ku saabsan daroogada.

"Euvaks" sidoo kale waa qalab ku caan ah, laakiin waalidka dareento ma aha sida wax ku ool ah sida "Engerix". Reviews muujiyaan in ay tahay version labaad ee tallaalka inta badan ku taliyeen dhakhaatiirtu.

diyaarinta ma waxaa ka mid ah fayrasyada, waxa uu leeyahay maya sheyga dilay, inta badan ka yar nool. Tallaalka Aasaaska - antigen sameeyay dhaqanka khamiir saafi ah.

Sameynta tallaal kasta oo keeni kara in a dhantaalan ku meel gaar yar ee caafimaadka, laakiin hepatitis B «Engerix" inta badan si wanaagsan loo ilaaliyo. In xaaladda caadiga ah ee habka difaaca jirka had iyo jeer waa jawaabta la doonayo difaaca joogo.

Ma aha qof kasta uu doonayo in la talaalo, laakiin waa in aan fahamsanahay in iyaga oo aan aad halis u ah in cudurro badan oo khatar ah. Marka daroogada tallaalka "khabiir Engerix 'tixgelinayo tiro badan oo ah arrimo kala duwan, taas oo meesha dhaawaca suurto gal ah in caafimaadka. In ku dhow dhammaan kiisaska, isticmaalka waqtiga ee tallaalka mahad aadan horumarinta cudurka.

Joog caafimaad!