Hormoonnada ganaca - muhiimadda noolaha.

function ganaca. function hormoonada jidhka ganaca waxaa keena unugyo gaar ah oo ka mid ah Islets of Langerhans - α-, β-, D- iyo F-nooc. The unugyada kasta oo ka mid ah noocyada kuwaas qarsan hormoonnada qaarkood islet-unugyada β soo saaro insulin,-unugyada α - glucagons, D-unugyada - somatostatin, secretin iyo pankreogastrin, walxaha hormone-sida F-cell waxaa ku dhexsameeysmo jirka (iyo lipokain vagotonin). Sidaa darteed, xubin muhiim ah oo ku lug leh sharciyeynta geeddi socodka dheefshiidka, waa beeryarada. Hormoonnada, dhexsameeysmo qanjirka this saameeyaa dhammaan noocyada shiid ee jirka. Insulin furay LV Sobolєv ee 1902. In qarnigii 19-dhisay qaab-dhismeedka hormone iyo Avv la soo saaray.

hormoonnada ganaca: insulin. Bartilmaameedyada of insulin free yihiin unugyada beerka, murqaha iyo unugyo. Insulin saamaysaa dhamaan noocyada is-weydaarsiga: protein, carbohydrate, la egyahay, laakiin ay saamayn ku-shiid ee carbohydrates bartay ugu fiican. First of dhan, insulin kordhiyaa permeability ee xuubka unug in sonkorta iyo sidaas bixisaa ay kala iibsiga ka dhiigga si nudaha ku. hormone Tani waxay shidaa enzyme fosfoglyukotransferazu (geksozokinazu) iyo sidaas bixisaa beddelidda ee glucose si sonkorta 6-phosphate. natiijada u dambaysa ee saamayn insulin on-shiid carbohydrate waa hoos u uruureen gulukooska ee dhiigga (hypoglycemia) oo raasamaal ah glycogen in muruqa, beerka iyo xubnaha kale. Sababo la deficiency unugyada insulin lumiyaan awoodda in ay isticmaalaan glucose. Its xaddiga dhiigga ku tartiib tartiib ah u kordhiyaa (hyperglycemia), iyo iyada oo uu bilaabo inuu u istaagaan soo baxay kaadida (glycosuria).

Ka sokow insulin wanaajisaa gaadiidka glucose ka dhiiga acids amino firfircoon, galay cytoplasm unugyada lymph, waxay shidaa qoraal iyo turjumidda, taasoo keentay in Avv borotiinka wanaajiyey.

Saamaynta of insulin on-shiid la egyahay sababa xaqiiqda ah in waxa uu siiyaa isticmaalka carbohydrates , waayo, ereygu wuxuu ahaa ee acids carboxylic sare, waxaa hore u sameeyay triacylglycerols iyo subaga kale. Dhinaca kale, insulin hakiyo lipase unugyada, oo ay ku jirto sabab u Iscelin of formation xerada. formation ku filnayn of insulin ee jirka ku weheliyay nabaad kor u kacay ee acids amino, kaas oo ugu dambeyntii keenta in raasamaal ee ammonia iyo HOL in dhiigga. Dhaqaajiso lipolysis, taasoo keentay in raasamaal dhiigga acids dufanka leh oo lacag la'aan ah, meydadka ketonka iyo kolestaroolka.

Hormoonnada ganaca: glucagons. bartilmaameedyada Glucagon waa unugyada beerka, unugyada adipose iyo muruq, laakiin mid ka mid ah ugu weyn waa beerka, kaas oo la shaqeysiin hoos phosphorylase saamayn glucagons ah, taas oo iyana shidaa hydrolysis ee glycogen. Sidaa darteed, xaddiga glycogen beerka hoos iyo kor u sonkorta dhiigga. Intaa waxaa dheer, glucagons wanaajisaa gluconeogenesis, shidaa lipolysis unugyada adipose iyo sidaas ka hortagtaa horumarinta cayilka. Tan waxaa ku weheliyay formation of xaddi badan oo meydadka acetylsalisylsyre-CoA iyo ketonka. Waxay yaraysaa dheecaan glucagons in hyperglycemia iyo kordhisaa culayska fekerka iyo shaqo adag.

Hormoonnada ganaca: somatostatin. Incretion igibiruet insulin firfircoon hormone iyo glucagons, gastrin iyo dheecaan gastrinstimuliruyuschuyu doorashada ee Aashito. Xadgudubyada incretion ee insulin, glucagons, iyo somatostatin xambaarsan horumarinta diabetes. Cudurka Tani waxa lagu gartaa tabar guud ah, hyperglycemia, glycosuria, polyuria (lacagta maalinlaha ah ee kaadida korodhka by 3-5 jeer), waxaa jira cataract diabetic, sentigiiba corneal waxaa laga soo minguuriyay.

Hormoonnada ganaca: lipokain iyo vagotonin. Lipokain - walax hormone-sida taasoo ka hortagaysa beerka dufanka leh, waxaa kobciyaa qayilo ee dufanka, acids dufanka leh iyo outlet laga soo gooyay beerkii si nudaha ku, kor u biosynthesis of phospholipids. Vagotonin wuxuu kobciyaa waxqabad ee habdhiska ku parasympathetic, gaar ahaan dareemaha vagus, shidaa geedi socodka hematopoiesis.