Nudaha - waa maxay? liiska daroogada

wakiilada cytotoxic - wakiilada taas oo hoos habka Qaybta unugyada. Joogtaynta nolosha u shaqeeyo oo ku salaysan awoodda unugyada si ay u kala qaybiyaan, halka unugyada cusub meesha of jir ah, iyo wax duug ah, siday u kala horreeyaan, dhimanayaan. xawaaraha geedi socodka this bayoloji go'aamiyey in jidhka la taageeray by dheelitirka adag ee unugyada, kuna waari dhexdeeda waa cajiib in xubin kasta oo soo baxa habka dheefshiidka heerar kala duwan.

Laakiin mararka qaarkood heerka of kala qeybinta unug uu noqdo mid aad u weyn, unugyada jirka aadan haysan waqti ay ku dhintaan. Sidaas waa formation of burooyinka, in si kale loo dhigo - burooyin. Waxay ahayd waqti this noqdo khuseeya su'aasha ah ee nudaha - waxa uu yahay iyo sida ay u caawin karaan in lagu daaweeyo kansarka. Iyo in ay ka jawaabto, waa in aad ka fiirsan dhammaan dhinacyada kooxdan oo ah daroogada.

Nudaha iyo burada

Xaaladaha intooda badan ku dhaqanka caafimaad isticmaalka nudaha dhacdaa beerta cudurka kansarka, si aad u yarayso koritaanka buro. Inta lagu jiro daaweynta, daroogada ayaa wax ku ool ah oo ku saabsan unugyada jidhka oo dhan, sidaas hoos gaabis shiid ka dhacaan dhammaan unugyada. Laakiin kaliya in burooyinka halista saamaynta nudaha waxa lagu sheegay buuxa by gaabis heerka horumarka kansarka.

Nudaha iyo geedi socodka, shalalka

Sidoo kale, wakiilada cytotoxic isticmaalo in lagu daaweeyo cudurrada, shalalka, iyadoo ay sabab u dhaqdhaqaaqa bahal ah ee habka difaaca jirka antibodies baabbi'in cudur ma galaan unugyada iyo unugyada u gaar ah jirka ee. saamayn Cytostatic on dhuuxa lafta, yareynta hawlaha ee difaaca, ku dheehan yahay cudurka wuxuu leeyahay fursad uu si ay u tagaan dembidhaafka.

Sidaas darteed, daawooyinka cytotoxic loo isticmaalo cudurada soo socda:

• burooyin kansar malignant ku jira marxaladaha hore;
• lymphoma,
• leukemia,
• lupus erythematosus oo nidaamsan;
• arthritis;
• vaskulitis;
• Sjögren syndrome,
• scleroderma.

Iyadoo loo arkaa calaamado muujinaya ee soo dhaweynta ka mid ah daroogada iyo hab ay of saamaynta ay jidhka, waxa uu noqonayaa sida shaqada nudaha, cad waxa ay tahay, iyo marka ay tahay in la isticmaalo.

noocyada kala duwan ee kuwa nudaha

Nudaha, kuwaas oo hoos ku qoran, waxaa aan ku xaddidnayn qaybahan, laakiin waa caado ah in la kala saaro, kuwaas oo 6 qaybood ee daawooyinka.

1. alkylating wakiilada cytostatic - wakiilada in ay leeyihiin awood u leh inay dhaawici DNA unugyada kaas oo waxaa lagu gartaa heerka sare ee fission. Inkastoo heerka sare ee wax ku-oolnimada, daroogada adag-dulqaadan, oo ay ku jiraan saamaynta daawada inta badan waa cudurada ee beerka iyo kelyaha sida hababka ugu muhiimsan ee sifeynta. Iyada oo la adeegsanayo sida ka mid ah:

• iniin khardal,
• taagayo nitrourea;
• alkyl;
• ethylenimines.

2. wada jir, wakiilada cytotoxic asal ahaan warshadda - waxyaabaha saameyn la mid ah, laakiin la Halabuurka dabiici ah:

• taxanes;
• wada jir vinca;
• podophyllotoxins.

3. wakiilada cytotoxic, antimetabolites - daroogada in la xakameeyo walxaha ka qayb qaadashada habraaca ku formation buro, oon joojinta kobaca:

• Doodeen folate,
• analoogga purine;
• Doodeen pyrimidine.

-Antibiotics 4.Tsitostatiki - wakiilada antimicrobial hawlaha antitumor:

• anthracyclines.

5. wakiilada cytotoxic, hormoonnada - dawooyinka kansarka in la yareeyo wax soo saarka ee hormoonnada qaarkood.

• progestins;
• antiestrogens;
• estrogens;
• antiandrogens;
• inhibitors aromatase.

6. antibodies Monoclonal - antibodies kiimikaysan abuuray isku halkan ku toosa unugyadooda gaar ah, haddii ay taasi - burooyin.

diyaarinta

Nudaha, liiska daroogada taas oo hoos lagu soo bandhigay, ayaa la soo saaray oo kaliya on qoro iyo waa la qabtay oo kaliya on xaaladaha adag:

• "Cyclophosphamide";
• "Tamoxin";
• "Flutamide";
• "Sulfasalazine";
• "Chlorambucil";
• "Azathioprine";
• "Temozolomide";
• "Hydroxychloroquine";
• "Daawada methotrexate".

Liiska daawooyinka ku haboon lahaa qeexidda "wakiilada cytostatic" waa mid aad u ballaadhan, laakiin daawooyinka kuwanu waxay leeyihiin qoray by dhakhaatiirta oo intaa ka badan. Diyaargaraw waxaa si gaar ah u doortay inay bukaanka aad si taxadir leh, dhakhtarka u sharaxayaa bukaanka waxa dhibaatooyinka soo raaca kuwa nudaha keeni, waxa ay tahay iyo haddii ay suurogal tahay in iyaga looga fogaado.

waxyeellooyin

habka cudur-aqoonsiga waa in loo xaqiijiyo joogitaanka qof ka mid ah cudur halis ah kaas oo daaweyn loo baahan yahay kuwa nudaha. Dhibaatooyinka ay keento daawooyinkan loogu muujiyo si cad, kama liidata kaliya dulqaadan by bukaanka, laakiin sidoo kale qaadaan halis ku ah caafimaadka aadanaha. In si kale loo dhigo, qaata daawooyinka cytotoxic - waxaa had iyo jeer waa khatar aad u wayn, laakiin kansarka iyo cudurada, shalalka, halista la'aan daaweynta uu ka badan yahay halista ah ee dhibaatooyinka suurogal ah in daroogada.

The saameynta dhinaca ugu muhiimsan ee nudaha waa ay saamayn xun ku dhuuxa lafta, iyo halkan nidaamka oo dhan hematopoietic. Iyada oo la isticmaalo daba dheeraaday, kaas oo sida caadiga ah loo baahan yahay in therapy kansarka iyo kasoobaxyo, iyo geedi socodka, shalalka, laga yaabee horumarinta leukaemia.

Laakiin xitaa haddii la baajin karin dhiigga cudurka kansarka, beddeli ka kooban dhiig ciday saamayn hawlgalka nidaamyada oo dhan. Haddii nafwaayay sii kordhaya ee dhiigga, dhammaantood kelyaha ha la wada saameeyey, sida xuubka glomerular been load weyn, oo sababtay in ay dhaawac karo.

Inta lagu guda jiro soo dhaweynta ka mid ah kuwa nudaha waa in uu diyaar u yahay caafimaadka masaakiinta joogto ah u noqon. Bukaan-kan koorso of daaweyn la kooxdan tegey, ogow dareenka joogta ah daciifnimo, dawakhsanaan, awood la'aanta in ay xooga saarto hawsha. Waxaa ka mid ah cabashooyinka caadiga ah waxaa ka mid ah madax xanuun, taas oo analgesics joogo si joogto ah iyo si dirqi ah fogaadaa.

Dumarka in muddada daryeelka waxaa inta badan soo food leh xadgudubyada caadada iyo awood ay ku uuraysato ilmaha.

Xanuunka nidaamka dheefshiidka ayaa lagu muujiyey sida lallabo iyo shuban. Inta badan this sababa doonayay dabiiciga ah si ay u xakameyso uu cunto iyo in la yareeyo xaddiga cuntada, taas oo keenta in anorexia.

Ma aha khatar u tahay caafimaadka, laakiin saamaynta dhinaca xun ee daroogada cytostatic waa timo ah oo daataan on madaxa iyo jidhka. Ka dib markii la joojiyo oo koorsada, sida caadiga ah, koritaanka timaha dib.

Iyadoo ku saleysan, waxaa suurtagal ah in ay xoogga saaraan in jawaabta su'aasha ah ee nudaha - waxa uu yahay, waxa ku jira macluumaad ma aha oo kaliya oo ku saabsan faa'iidooyinka noocan ah daroogada, laakiin sidoo kale khatar sare si ay u ah caafimaadka iyo ladnaanta waqtiga ay codsiga.

xeerarka Admission nudaha

Waxaa muhiim ah in la fahmo in cytostatic ah uu saameyn toos ah ku hawl ah ee habka difaaca jirka, waxa anada. Sidaa darteed, inta lagu guda jiro qofku noqdo mid u nugul cudurka kasta.

Si looga hortago cudurka, waa in aad buuxiso dhammaan tallaabooyinka ammaanka muuqan meelaha uruureen waaweyn ee dadka, xirtaan faashad faashad difaaca iyo u isticmaalaan hab hoose ee ilaalinta antivirus (cadar oxolinic) si looga fogaado hypothermia. Haddii cudurka caabuqa neefsashada weli waa ay jiraan, waxaad u baahan tahay in ay raadsadaan daryeel caafimaad oo degdeg ah.

Sidee si loo yareeyo saamaynta dhinaca?

daawo Modern waxay fursad si loo yareeyo darnaanta waxyeellooyin ka dhacaya bukaanlayda qaadato daawooyinka cytotoxic. daroogada Gaarka ah in loo joojiyo reflex hungaaeada ee maskaxda ka dhigaya suurto gal si ay u ilaaliyaan xaalad caadi ah oo caafimaad iyo qaab lagu jiro daaweynta.

Sida caadiga ah, kiniin la aroor hore loo qaaday, ka dibna waxaa lagu talinayaa in la kordhiyo hab la cabbo ilaa 2 litir oo biyo ah maalin kasta. Nudaha badan saxarrada kelyaha, sidaas darteed qayb ka ah waxaa laga yaabaa in ay u degaan in unugyada kaadi haysta, bixinta diiqayo. Xaddi badan oo dareeraha iyo firaaqeynta soo noqnoqda waxay suuro gelineysaa in la yareeyo darnaanta waxyeellooyinka daroogada cytostatic on kaadi haysta. Gaar ahaan muhiim ah in aad si taxadar leh u faaruqiso kaadi haysta inta aadan seexan.

Sahan lagu jiro daaweynta

nudaha Admission u baahan tahay baaritaanka joogtada ah ee jidhka. bishiiba hal mar aan ka yarayn, bukaanka waa inay ku aflaxaan imtixaanka oo muujinaya waxtarka kelyaha, beerka, nidaamka dhiigga,

• CBC,
• chemistry dhiig on heerka kariyaatiniin, ALT iyo AST;
• Falanqaynta a full of kaadida;
• cabbiro CRP.

Sayidka, og dhammaan macluumaadka la xiriira oo ku saabsan waxa loo baahan yahay nudaha, waxa uu yahay, noocyada daroogada yihiin iyo sida loo qaado, in aad ku tashan karaan therapy ah saadaal wanaagsan kansarka iyo cudurada, shalalka.