Waa maxay cudurka Addison ee?

Cudurka Addison ee waxay dhacdaa marka cillad ee kiliyaha adrenal. Cudurkaan waxaa laga helay in ragga iyo dumarka, inta badan da'da dhexe (30 ilaa 40 sano) labadaba. Waa cudur dhif ah, kaas oo ka diiwaan gashan hal qof per 100 Population kun.. Cudurka Addison Biermer laga yaabaa in ay sabab u tahay geedi socodka, shalalka, cudurrada faafa (syphilis, qaaxada iyo adrenals tiifowga), iyo in amyloidosis iyo burooyinka halista ah. In 70% dadka bukaanka ah, cudurka ku dhacaa sabab u ah fashilaad in habka difaaca jirka (antibodies ah ayaa bilaabay in ay qaataan unugyada jirka maydadka shisheeye ah, weerarka iyo iyaga u baabbi'in). Burburintii oo ka mid ah unugyada kiliyaha adrenal hoos gluco ereygu iyo mineralocorticoids (yaqaano Cortisol, 11-deoxycorticosterone, aldosterone). Seynisyahanno waxay muujiyeen in glucocorticoids nidaaminaya geedi socodka lagmamaarmaanna kala duwan ee jirka (dejisa cadaadiska dhiigga, fiirsashada insulin, waxaa ku lug sharciyeynta Avv borotiinka, subaga iyo carbohydrates).

Gipokortitsizm inta badan lagu arkay bukaanka loola dhaqmo si ka hormoonnada ah kiliyaha adrenal. Xaaladaha intooda badan, etiology cudurka weli la garanayn. kaafi adrenal tilmaamay inay galeen hoose iyo sare. failure Primary uu yeesho kulankii unugyada adrenal, iyo sare - sabab u ah kicinta aan ku filnayn ee hormone adrenocorticotropic.

Calaamadaha Cudurka Addison ee

calaamadaha Clinical cudurka sababa deficiency in macdanta shaqeeyo iyo glucocorticoids. Muuqaaladan ugu caan ku tahay daciifnimo, hypotension, caloosha iyo mindhicirka aan shaqeynin (yalaalugo, rabitaanka cuntada oo luma, matag, calool, shuban taas oo inta badan lagu bedelay). Qaar ka mid ah bukaannada hypochlorhydria.

Cudurka Addison ee waxaa la socda caro kordhay ama dabeecadeed niyadjab, madax xanuun joogta ah iyo hurdo la'aan. X-ray ee xabadka ayaa muujinaya hoos u dhac ku size wadnaha. electrocardiogram The diiwaan gelinayaa calaamadaha hyperkalemia (fiirsashada potassium sare ee dhiiga). midabka maqaarka ma turjumayo darnaanta cudurka, si kastaba ha ahaatee, kororka ama waxay taasi yareyn ee daaweynta ee caddayn ah oo ku saabsan waxtarka of tallaabada ku daweyn.

Cudurka Addison ee waxa lagu gartaa asal ahaan ka mid ah calaamadaha sare ka yar daran. Aad dhif cudurka muuqato aan midabka jirka (sidaas horyaalka ee "Addison cad"). Sababta ugu weyn ee cudurkan waa adrenals qaaxada. Maqnaanshaha daaweynta ku haboon cudurka Addison ee adag. calaamadaha Clinical maqalka: lallabo, matag, shuban, dhiig karka maratay dhibciyo, sii kordhaya fiirsashada of potassium in dhiigga. In dhiigga durugsan ee Nitrogendoksid haraaga kordhiyaa tirada unugyada dhiigga cas, unugga. Sidaa darteed, haddii inta lagu jiro mudada of bukaanka addisonicheskogo dhibaato ma bixiso kaalmo waqtiga, uu dhinto la calaamadaha kelyaha iyo cudurrada wadnaha.

Beegyada uu shaybaarka ee ugu muhiimsan ee cudurka waa content ee 17-OCS ee plasma iyo 17-KS kaadida, iyo sidoo kale hoos u dhac in heerarka sonkorta dhiigga. Baaritaanka Morphological dhiigga muujinaysaa lymphocytosis, eosinophilia iyo ESR raagay.

Cudurka Addison ayaa kala ka mid ah cudurada soo socda: diabetes naxaas ah, pellagra, arsenite sumowga iyo Bismut Argentum. Cudurku wuxuu sida caadiga ah leeyahay koorso chronic la kahadlay wareegsan. Addison Biermer darnaanta cudurka go'aamiyo darnaanta ka mid ah calaamadaha ugu weyn ee cudurka, iyo sidoo kale tirada daawooyinka in loo baahan yahay in ay mag-yaridu adrenal.