Daawada "Gynestril": tilmaamaha loo isticmaalo, analogs iyo dib u eegis

Sida loo qaato daawada "Gynestril"? Tilmaamaha isticmaalka dawadan lagu tilmaami doonaa in qalabka of this article. In u, waxaan ku soo bandhigaynaa jawaabaha dadka bukaanka ah, daroogada, ay sifooyinka pharmacological, tilmaamo iyo sababo.

The Halabuurka, qaabka

Waa maxay qaybaha ka mid ah daawada "Gynestril"? Shuruucda LABAGEEDI OO in hab this, waa in ay qayb firfircoon waa mifepristone. Sidoo kale medicament wuxuu ka kooban yahay waxyaabaha dheeraadka ah ee foomka of istaarijka baradho, lactose, cellulose mikrokristallin, povidone, milmahayn magnesium iyo istaarijka sodium carboxymethyl.

Soo iibso daawooyinka waxa ay noqon kartaa in kiniin, kuwaas oo la soo baakadeeyey ee baakad kartoonada.

sifooyinka pharmacological daawo

Ma ogtahay in uu yahay maandooriye "Gynestril"? Tilmaamaha loogu isticmaalo caawin doonaan inaad fahamto mabda'a of tallaabo daroogada this, iyo wuxuu kuu sheegi doonaa in hoos wax tilmaamaya in ay la isticmaalo ee dhaqanka caafimaad.

medicament viewed waa wakiilka ah steroid antigestagens asal dardaro. oggolyahay ayaa ku daweyn of daroogada sababtoo ah halka ay ka kooban.

Marka la helo mifepristone ee jidhka bini'aadamka waxaa uu hakiyo saamaynta progesterone, laakiin ma muujiyaan waxqabad progestational.

Khubarada ogow iska soo horjeeda ee daroogada ay sabab u tahay tartan la glucocorticoid qabanaya heer receptor ah.

Sida la og yahay, doorka ugu weyn ee formation of leiomyoma makaanka la siiyaa dumarka, gaar ahaan progesterone. Marka tan la eego, mifepristone ahaan loogu talo galay bukaan si loo joojiyo receptor progesterone ah. Natiijada daaweynta ay tani ku dhacdo in dib u dhac koritaanka buro, iyo sidoo kale dhimista tirada fibroids , iyo makaanka.

The guryaha pharmacokinetic daroogada

Waa maxay astaamaha uu leeyahay daroogada pharmacokinetic "Gynestril"? Tilmaamaha, dib u eegista la kulmay dhakhaatiirta ayaa sheegaya in ka dib markii maamulka afka tirada ugu badan ee daroogada ayaa lagu arkay oo ku saabsan 80 daqiiqo. Waxaa intaa dheer, ay bioavailability waa 69%.

daroogada borotiinada Plasma tixgeliyo xidhana in 98% (la albumin iyo Alfa-1 acid glycoprotein).

Ka dib markii wajigii qaybinta dhacdaa wajiga reebay gaabis ah. In fiirsashada dhiigga daroogada waa la dhimay by badh (u dhaxayso 15 iyo 72 saacadood).

Tirtiridda ee daroogada waa deg deg ah, iyadoo muddo 18 saacadood.

Tilmaamayaasha

From oo daroogada "Gynestril" waxa lagu meelaynayaa karaa? Tilmaamaha loogu isticmaalo, khubarada dhabta ah soo jeedin ka muujinaya soo socda:

• daaweynta leiomyoma, makaanka,
• joojinta uurka intrauterine ilaa 42 maalmood;
• induction (ama kicinta) ee shaqada (oo ay ku jiraan ugu dheer);
• hortagga degdegga ah (postcoital) ee unreliability loo isticmaalo ka hortagga uurka, iyo in muddo ka dib galmo aan layska ilaalin.

sababo

"Gynestril" daroogada ilmo iska soo ridid waa in aan la isticmaali karaa marka:

• uurka Caafimaad ahaan la xaqiijin;
• uurka ectopic la ogolaan karo,
• uurka oo ka kacay ka dib bixitaanka of hab ka hortag oo hormoon, ama adigoo isticmaalaya uurka ah intrauterine;
• uurka 42 maalmood ka dib.

Marka leiomyoma daroogada waxaa ka mamnuuc ah inuu ku meeleeyo in arrimaha soo socda:

• gelinayn at qanjidhada myom submucous;
• in burooyinka ugxansiduhu,
• kelyaha gooba;
• haddii qiimaha leiomyoma waa weyn.

Kiniiniga "Gynestril" for xoojiyo foosha looma isticmaalo in:

• preeclampsia daran;
• bandhigga uurjiifka aan caadi ahayn;
• pre-eclampsia,
• eclampsia;
• risk ama uurka post-dheer,
• isu dheelitir la'aanta size of madaxa iyo hooyooyinka iyo miskaha uurjiifka,
• gashatid baarin ka mareenka xubnaha taranka inta lagu guda jiro uurka.

Ma ku sababo daroogada guud "Gynestril"? Tilmaamaha siinayaa su'aashan waa ku raaca. reebay waxaa ka mid ah shuruudaha soo socda:

• porfyri;
• therapy muddo dheer la glucocorticoids;
• anemia daran;
• kelyaha ama beerka (nooc kasta);
• xad gudub ku ah hemostasis (daaweynta xinjirowga ee la soo dhaafay);
• extragenital dabeecadda daran,
• cudurada nidaamka dumar taranka, taas oo qof bararka,
• diidmo (oo ay ku jiraan taariikhda);
• nikotinozavisimost, gaar ahaan ka dib da'da 35.

Iyada oo taxaddar dheeraad ah marka ay qaadanayaan dawadan:

• cudurada sambabada obstructive (qof chronic);
• wadnaha,
• hypertension,
• arrhythmia;
• neefta bronki,
• rabshooyin garaaca wadnaha.

Drug "Gynestril": war

Waayo, joojinta uurka (dib u eegista bukaanka ee medicament waxaa lagu xoogaa dheeraad ah looga hadli doonaa), daroogada this waa in la siiyaa oo kaliya takhasus cidhiidhi ah. Iyo sii wado qaadashada kiniiniga kiiskan oo keliya in joogitaanka dumarka.

Tan iyo isticmaalka daroogada "Gynestril"? Tilmaamaha joojinta uurka sheegayaa in ay lagama maarmaan tahay in la isticmaalo dhoos keli ah 600 mg.

Daawada waxaa la wareegay 1-1.5 saacadood ka dib cuntada iyo hoos 100 ml oo biyo ku maydhay.

Si loo kordhiyo waxtarka daawada laga yaabaa dheeraad ah Ujeedada 400 mg misoprostol (i.e., prostaglandin dardaro E1).

Ka dib markii la helo kiniin bukaanka waa in la kormeero dhalmada ugu yaraan laba saacadood. Ka dib markii 1.5 maalmood ama 2 qaadeen ultrasound. Xitaa ka dib markii 1-2 toddobaad si ay u qabtaan baaritaan caafimaad iyo ultrasound soo noqnoqda iyo hubi heerka dhiigga hCG si loo xaqiijiyo dhicin.

Haddii ay sidaa tahay, haddii daroogada ma caawin (ie, uurka sii), dhakhtarka ku talinaysaa nuugid baadhitaan dheeraad ah (histology) natiijada habka a.

Si aad u kicin hawlaha guud, daroogada mar ay maamusho ee qiyaasta ah 200 mg. Waxay taas samayn in joogitaanka dumarka. Ka dib markii hal maalin, cadadka daawada lagu celceliyo at dose oo isku mid.

2-3 maalmood ka dib, ku qiyaas ballaarinta marinka dhalmada. Sayidka loo ogaado suurtagalnimada of isticmaalka dheeraad ah "oxytocin" ama prostaglandins.

Sida loo isticmaalo daroogada leiomyoma makaanka "Gynestril"? Guide sheegayaa in marka la diyaarinayo cudurka sida caadiga ah waxaa maamula in dhoos keli ah 50 mg. Daawada waxaa afka laga qaato muddo saddex bilood ah.

Iyadoo la tixgelinayo uurka post-coital, dhakhaatiirta ku talinaynaa isticmaalka medicament ah loo tixgeliyaa in lacagta ah 10 mg muddo saddex maalmood ah ka dib galmada aan layska ilaalin (eegin wajiga caadada). Qaadashada kaniiniyada kiiskan waa la jecel yahay laba saacadood ka hor ama ka dib cuntada.

xaaladood oo badinta

Isticmaal daroogada at dose oo ah wax ka badan laba garaam oo sababaha wax saameyn xun. Marka la isticmaalayo in ka badan inta ku qeexan daawada laga yaabaa in bukaan sameeyaan la'aan adrenal, taas oo u baahan daaweynta calaamadaha.

waxyeellooyin

Qaadashada medicament "Gynestril" inta badan sababa waxyeelo sida madax xanuun, yalaalugo, wareer, matag, finan, shuban, amenorrhea, gashatid lohiometra, subinvoljutcija, makaanka, hyperthermia, emmeniopathy, daciifnimo, niyad-jabka ah ee caabuq-galeenka iyo appendages, raaxo iyo xanuun caloosha. Haddii aad isku aragto calaamadahan, hubi inaad la tashato dhakhtar.

isdhexgalka daroogada

Waxaa laguma talinayo in ay qaataan daawada "Gynestril" ay barbar socdaan NSAIDs. Sidoo kale waa in la ogaadaa in lagu daro glucocorticoids loo baahan yahay in la kordhiyo qiyaasta, laakiin kaliya ka dib markii uu la tashado dhakhtarkaaga.

talooyin gaar ah

Waxaa laguma talinayo in ay daawada u qaataan sidii uurka si joogto ah.

Marka aad isticmaasho "Gynestril" Abortion waa in had iyo jeer ku wargalisaa bukaanka ku saabsan fursadaha kale ee nidaamka this, gaar ahaan haddii ka dib markii laba toddobaad ee uurka ugu sii socoto ama uu jiro ilmo iska soo ridid ah aan dhamaystirnayn (khatarta suurto galka ah ee aan caadiga ahayn ee ilmaha caloosha ku).

Price iyo analogues lacag

Analogs "Maamulka Gynestril" daroogada waa daawooyinka soo socda: "Ginepriston", "Penkrofton", "Agesta" "mifepristone", "Zhenale", "Mifolian", "Mifegin", "Mifepreks", "Miropriston".

Price loo arkaa daawooyinka waa mid aad u sarreeya iyo ka dhigan tahay in 5000-6000 rubles.

Reviews of medicament

comments togan ama taban aan shaki iyo gaar ah oo ku saabsan "Gynestril" diyaarinta lahayn. Si kastaba ha ahaatee, bukaanada ugu hoosaysa ka jawaabo ku saabsan qalab this. Waxay ku doodayaan in ay tahay mid aad u wax ku ool ah iyo xoogaa ammaan u soo dhaweynta.

Sidoo kale waa in la ogaadaa in dadka qaar ka mid ah, on lid ku ah, waxaa inta badan lagu arkay at horumarinta waxyeellooyin.

Dhammaan dib u eegista, kuwaas oo soo jeedinaya in qaadashada daawada this waa in la sameeyaa oo keliya ka dib markii la tashanaya dhakhtarka.