Niyad jabka "Velaksin": Kurtumm bukaanka, tilmaamaha loo isticmaalo, analogs

Waxaan ka iibsan kartaa kiniinada farxadda aan qoro? Liiska waxyaabaha sida weyn yahay. Tan waxa u sabab xaqiiqada ah in la qabatimo, iyo Koox ka mid ah waxyeelo. Sidaa darteed, ka hor inta aysan hab sida, xaqiiji inaad booqato dhakhtar takhasus u leh.

warbixin guud

Murugada waxa aan la daaweyn by daroogada. Laakiin si loo hagaajiyo hawlaha of habka dareemayaasha jirka, dhakhaatiir badan oo weli qori bukaanada ay murugada kala duwan. Mid ka mid ah iyaga ka mid ah waa daroogada "Velaksin". Kurtumm oo ku saabsan qalab this iyo sifooyinka iyo tilmaamaha loo isticmaalo in lagu hoos lagu soo bandhigay doonaa.

Halabuurka The oo daroogada ah, qaabka wax soo saarka

In waxa foomka u soo saarta niyad jabka ah sida "Velaksin"? Kiniiniga iyo kaabsuullada - yihiin noocyada keliya ee daroogada.

Kiniiniga "Velaksin" waa cadaan, xardhay hal dhinac "E741", oo qaab wareeg ah guri iyo chamfer. Ay qayb firfircoon waa venlafaxine, oo ay matalayaan ee foomka of hydrochloride ah. Sidoo kale waxaa ka mid ah in daawada waxaa ka mid ah qaybaha kaabayaal sida ammooniya Kolloidol silica, laktosmonohydrat lactose, sodium glycolate noqde, milmahayn magnesium iyo MCC.

kiniiniyada buuxiyey oo ku yaal baakad fin iyo kartoonada siday u kala horreeyaan.

Drug "Velaksin" - kaabsoosha, tilmaamaha loo isticmaalo kuwaas oo ku lifaaqan ee baakadaha, waraaqaha, gelatin oo adag. Waxay leeyihiin cap orange-brown iyo substrate ah midab. qayb firfircoon ee foomkan sidoo kale waa venlafaxine xarunta a. Waxa intaa dheer in uu ka kooban daawada waxaa ka mid ah maaddooyinka oo dheeraad ah.

Sida shuqullada daroogada?

"Velaksin" - jiil cusub oo anti-dejiye. Sida laga soo xigtay dhismeedka kiimikada ee ay walax firfircoon uusan ka tirsan fasalka kasta oo loo yaqaano ee lidka diiqadda (tus, tricyclic, tetracyclic, ama wax kale). Khubarada ayaa sheegaya in daroogada waa firfircoon enantiomer 2 racemate.

Mabda'a garoomada ka mid ah daroogada this la xiriira awoodda potentiate habdhiska gudbinta Suu dareemaha.

Sida laga soo xigtay tilmaamaha, venlafaxine iyo metabolite waaweyn (EFA ama O-desmetilvenlafaksin) matalaan inhibitors awood of reuptake ee norepinephrine iyo serotonin iyo inhibitors daciif ah reuptake dopamine. Waxaan ma dhihi karo in walxahan waxay awoodaan in ay yareeyaan dhaqdhaqaaqa beta-adrenergic ka dib markii daawada hal iyo joogto ah. EFA iyo venlafaxine si siman wax ku ool ka dhanka ah reuptake of neurotransmitters.

Maxaa kale waa daroogada cajiib ah "Velaksin"? Guide ayaa sheegay in qayb firfircoon ee daroogada ayaa xidhiidh ah la receptors n- iyo m-cholinergic, maskaxda α1-adrenoreceptors iyo histamine H1-receptors. Intaa waxaa dheer, waxa uu hakiyo tallaabo ee MAO oo uu leeyahay la mid ah ma la fentsiklidinovymi, opioid'ka, Benzodiazepin iyo NMDA-receptors.

The kinetics daroogada

haddii daroogada la nuugo, "Velaksin" (kiniin)? Tilmaamaha Isticmaalka dhigayaa in qayb firfircoon ee daroogada this waxaa si fiican u nuugo ka mindhicirka. Ka dib markii dhoos keli ah medicament in qiyaasta a of 25-150 mg ay fiirsashada ku badan yahay dhiigga la gaaro 2.4 saacadood ka dib. Sayidka venlafaxine waxaa si ballaadhan metabolized inta lagu jiro baas hore beerka. Haddii daroogada waxaa lala qaataa cuntada, halka ugu sarreysa fiirsashada korodhka ay by 27-30 daqiiqo ee plasma.

metabolite ugu weyn waxaa loo arkaa loola O-desmetilvenlafaksin. Its bar-nolosha iyo tirtiridda bar-nolosha ee venlafaxine waa 11 iyo 5 saacadood, siday u kala horreeyaan (wax soo saarka ee DASUURKA by kelyaha).

The kinetics daroogada xaaladaha caafimaad oo gaar ah

Drug "Velaksin" edbinta loo baahan yahay akhriska ee dadka qaba cirrhosis of beerka ku leeyahay muuqaalada kale ogeed. fiirsashada dhiigga daroogada kordhay bukaanadaan, iyo heerka of Digo, on lid ku ah, hoos u dhaca.

In la'aan kelyaha ee daran, kelyaha iyo ansixin guud ahaan dhexdhexaad ah EFA iyo venlafaxine waa la dhimay iyo waqtiga tirtiridda bar-nolosha la dheeraado.

Sidoo kale waa in la ogaadaa in jinsiga iyo da'da bukaanka uusan saamayn ku lahayn ee pharmacokinetics daroogada hoos tixgelin.

Tilmaamayaasha waayo,

Maxaa loogu baahan yahay qalab sida "Velaksin"? Isticmaalka daroogada this muujiyay niyad-jabka ah ee asal ahaan kala duwan (waayo, daaweynta iyo prophylaxis).

Mamnuucay ballanta

Under waxa xaaladaha uma isticmaali karo daawada "Velaksin"? Reviews bukaanka iyo dhakhaatiirta ku andacoodaan in daroogada this waa u si ay u helaan:

• halka helo MAO ;
• in xanuunada daran kelyaha,
• inta lagu guda jiro shakiyo ama aasaasay uurka;
• in xanuunada daran ee beerka,
• inta lagu jiro naas-nuujinta;
• in ay qaan-iyo carruurnimada, in uu yahay, ilaa da'da loo badanyahay;
• la dareen sare si ay daroogada.

Intaas waxaa sii dheer, daroogada this waa in si taxadir leh loo qaaday angina deganayn, Wadnaxanuun myocardial (oo ay ku jiraan cusub u guuray), hypertension, taariikhda gariir, tachycardia, miisaanka oo yaraada, kordhay cadaadiska intraocular, gulukooma xagal-xidho, cabista si ay dhiig ka axal iyo maqaarka, dalalka manic.

Drug "Velaksin" (kiniin): tilmaamaha loo isticmaalo

Niyad jabka "Velaksin" waa in kaliya la qaadan muddada hadhuudh ah. The dose bilaabo talinayaa daroogada waa 75 mg, kala qaybsameen 2 qiyaasood oo kala qaybsan (i.e., 37.5 mg laba jeer maalintii), maalin walba.

Haddii dhowr todobaad ee therapy ka dib, xaaladda bukaanka aan soo hagaagtay, qiyaasta maalinlaha ah waa kordhay ilaa 150 mg maalintii, in laba jeer oo kala (i.e., 75 mg laba jeer maalintii).

Haddii bukaanka u baahan yahay qiyaasta sare ee lidka diiqadda ah (tus, xaaladaha weyn ee murugada, ama xaaladaha kale ee u baahan daaweynta taagan), ka dibna farsamo ayaa cayimi karta 150 mg ah ee daawada in 2 saacadood, ka dibna si tartiib tartiib ah u kordhi qiyaasta by 75 mg (2-3 maalmood ka dib) si loo gaaro natiijada la rabay.

Sida laga soo xigtay tilmaamaha, qiyaasta ugu badan "Velaksina" waa 375 mg maalintii. Ka dib markii la gaaro tarin, waxaa lagu si tartiib tartiib ah hoos karaa in heerka ugu hooseeya.

Ka Hortagga Soo Noqoshada iyo daaweynta dayactirka

Daryeelka taageerada lacagaha wuxuu qaadan karaa muddo lix bilood ah. Xaaladdan oo kale, daawada qaataa qaabab yar.

In la'aan kelyaha fudud mudada kacmaha saxo loo baahan yahay. In cudurka la mid ah qiyaas dhexdhexaad talinayaa hoose by 25-50%. Sidoo kale waa in la ogaadaa in venlafaxine waa in aan la isticmaali ee kaafi kelyaha ee daran, tan iyo markii war ah kama on ammaanka therapy sida taariikhda, ma.

Dadka on kelyaha, waa in ay helaan 50% qiyaasta caadiga ah maalin walba ah ee daroogada ka dib markii darafyadiisa fadhiga.

Waayo, mudada kacmaha saxo la'aan cagaarshowga khafiif ah ayaa waxaa sidoo kale looma baahna. Marka uu cudurku waa qiyaas dhexdhexaad ah waa in la dhimay 50%. Iyadoo la tixgelinayo failure cagaarshowga daran, haddii ay taasi isticmaalka venlafaxine waa ka mamnuuc.

In dadka waayeelka ah, daroogada "Velaksin" waa in la isticmaalaa si taxadir leh xad-dhaaf ah. Tan waxa u sabab ku xadgudub suurto galka ah ee kelyaha. bukaanka waa in qori qiyaasta ugu hooseeya wax ku ool ah. Xaaladdan oo kale, bukaanka waa in ay ka yar kormeer caafimaad joogto ah.

cancel niyad jabka

Marka la dhameeyo helo daroogada in la tixgeliyaa waa in si loo yareeyo qiyaasta si tartiib tartiib ah (hal toddobaad gudahiisa). Waxaa loo baahan yahay si ay u dhawraan xaalad ka mid ah bukaanka, si loo yareeyo halista ah ee dhibaato la xidhiidha la baabiiyo of daroogada.

Waqtiga loo baahan yahay in la joojiyo dhamaystiran oo dawo ah, waxay ku xiran tahay qiyaasta, duration of therapy iyo shaqsi shaqsi.

waxyeellooyin

Waa maxay saamaynta aan la rabin ee daroogada waxay keeni kartaa "Velaksin"? Kurtumm sheegaya in horumarinta kuwii ama dhacdooyin kale oo loo kasin socda isticmaalka qalab this ku xiran qiyaasta helay.

Falcelinta ugu badan muujiyey dabeecadda xun waxaa ka mid ah kuwan soo socda:

• hypertension, hoos rabitaanka cuntada, riyooyin aan caadi ahayn, calool, hurdo la'aan, lalabo, bafinayo maqaarka, gariir, matag, xanuun murqaha, afka oo qalala,
• dhalanteed, hepatitis, miisaanka oo yaraada, tachycardia, hyponatremia, arxandarro, hypotension postural, dawakhaad, reaction manic, excitability habdhiska, hamaansigga, paresthesia, syndrome neuroleptic, maskax hurudda, syndrome serotonergic;
• kordhay cabirida xaalada muruqa, qalal, gubta, photosensitivity, haynta kaadida, anorgasmia;
• dhiig maqaarka, biyo bax aan caadi ahayn, menorrhagia, hoos u libido, dhidid,
• Torombositobiiniya, rabshooyin hoy, multiforme erythema, mydriasis, Stevens - Johnson, rabshooyin muuqaalka, dhadhanka oo yaraada, dheereyn waqti, tabar, finan maqaarka ah, daal, dhiig ficil-celintan jirka.

Sidoo kale waa in la ogaadaa in ay qiyaasta ay ka baxeen kadis ah gaariga loo arkaa ama la yareeyo waa u suurtoobaan reactions dhinaca sida habdhiska caro, daal, shuban, hurdo, nasasho la'aan, madax xanuun, paraesthesias, lalabo, dabeecaddaan, matag, dhidid, anorexia, hurdo la'aan, qalalan afka, walaaca, wareer iyo jaahwareer. Sida caadiga ah, calaamadahan way sahlan yihiin waxayna tag iyada oo aan wax daaweyn ah.

talooyinka

Iibiya in kiniinada farxadda aan qoro? Liiska wixii daawooyin aanay ahayn mid aad u weyn ( "Prozac", "Paxil", "Despres", "Azafen", "Faaris", "amitriptyline"), iyo daroogada "Velaksin" kuma jirto waxa ku jira. iibso farmasiyada, aad awoodo kaliya warqad dhakhtar ee.

Ka hor inta aad qaadanaysid dawadan hoos u eegid, gaar ahaan dadka qaba xanuunada niyad, waa in la tixgeliyaa itimaalka sare ah isku day is disho. Marka tan la eego, bilowga ah ee daaweynta daroogada talinayo in la isticmaalo in qiyaasta ugu yar iyo ka yar kormeer caafimaad dhow.

Dadka qaba xanuunada niyadda inta lagu guda jiro daawaynta murugada laga yaabaa in la horumariyo gobolka manic ama hypomanic.

Bukaan-socodka waa in ay hubisaa in si uu ugaga Digo baahida loo qabo in si deg deg ah u aragto dhaqtar jooga kiiska xubno urtikaria, finan ama dareen diidmo oo xasaasiyadeed.

Qaar ka mid ah bukaannada ku jira geeddi-socodka ah ee qaata venlafaxine arkay kororka dose-tiirsane ah ee dhiig-karka ah.

bukaanada waayeelka ah waa in loo digay xadgudub suurto galka ah ee dareenka dheelitirka iyo wareer horumarinta.

Inta lagu jiro daaweynta lacagaha waa inay iska ilaaliyaan qaadashada cabitaanka khamriga.

Niyad jabka "Velaksin": Kurtumm bukaanka, analogues wax soo saarka

Maxaa qof ayaa ku yidhi ku saabsan daroogada this bukaanka ah? macaamiisha badan ayaa sheegay tiro badan oo ah waxyeelo ka dhaca inta aad qaadanaysid dawadan. Inta badan daroogada this sababa dhibaato sida hurdo, daciifnimo, hurdo la'aan, qalal, fikirka aan caadi ahayn, niyad-jabka iyo wareer. Intaa waxaa dheer, bukaan oo qaar ka mid ah waxay ku andacoodaan in saamaynta kuwaas oo sii ka dib marka daaweeyntu kuu dhammaato. Sidoo kale, dadka isticmaala badan ka caban ku saabsan muuqaalka kore ee astaamaha u-barashada iyo ku tiirsanaanta.

Maxaa bedeli kartaa niyad jabka sida "Velaksin"? Analogs daroogada this aan in laga helo oo dhan iska-. Sida caadiga ah, khubaro waxaa ka mid ah kuwan soo socda: "Venlafaxine Sandoz", "Efevelon", "Alvent", "Nyuvelong", "Velafaks", "Dapfiks", "Voksemel", "Venlaksor", "Vensuert", "venlafaxine".