Daawada "Novocaine": tilmaamaha loo isticmaalo, qiimaha. "Novocaine" ee uurka

Daawo "Novocaine" waa daawada xanuunka wax ku ool ah. Daawada liiska ka mid ah qalabka caafimaad ee ugu muhiimsan.

guryaha pharmacological "Novocaine" daroogada

Tilmaamaha loogu isticmaalo muujinaysaa in daroogada ayaa suuxinta hawl dhexdhexaad maxalliga ah, waxaa si balaadhan looga isticmaalaa in dhaqanka caafimaad. Diyaarinta "Novocaine", taas oo salka daciif ah, channels sodium ayaa xiran by anada horumarinta iyo faafinta falalkooda dareemayaasha in fiiloyin dareemayaasha iyo dhammaato. Marka la helo saamaynta medicament beddel kara in unugyada neuronal, iyadoo saameyn weyn ku nasanayso iman kara lama siineyo. Daawada lagu cabudhibayo faafinta falalkooda xanuun.

Inta lagu guda jiro nuugid iyo isla markiiba galo dhiigga marka uu maamulo intravenously waxaa jira hoos u dhac excitability nidaamyada cholinergic durugsan, iyo dhalmo hoos u sii daayo acetylcholine dhammaato preganglionic. medicament The "Novocaine" (diiwaanka sharxayaa oo arrintan ku saabsan) tiraa dubaaxin ee muruqyada siman, yaraynaysaa excitability ee aagga motor of kiliyaha maskaxda iyo Wadnaxanuun ah.

Si loo isticmaalo faleebo, xal leeyahay antiarrhythmic, hypotensive, antishock, saamayn xanuunka, waxay kordhisaa xilliga madax adkaadeen, si weyn u yaraynaysaa conductivity ah, iyo excitability automaticity. At isticmaalka qaadasho sare laga yaabaa inuu dhaco xadgudub ku ah tabinta ee muruqa neerfayaasha, gariir lagu arkay.

Daawada ka saaraysaa jejebiyey saamaynta hoos u of stem maskaxda, saamayn nixiyay on hummaag polisinapticheskie. Waxay leedahay hawl yar suuxinta. suuxdinta dhexgalka Action socdaa 30 daqiiqo ilaa 1 saac. Xalka "Novocain" soo bandhigay bukaanada waayeelka intramuscularly ee marxaladaha hore ee heley wax ku ool ah cudurada la xiriira hawlaha oo yaraada ee habka dareemayaasha jirka, dubaaxin cerebral, wadnaha iyo dhiig-karka vascular dagaalami karnaa.

Daawada waxaa si liidata nuugo dhex-axaleedka ah. Marka la isku duro wakiilka firfircoon dhakhso dhiiga, waxaa hydrolyzed by esterases unugyo iyo plasma, la xirrira laba metabolite ugu weyn ee firfircoon: PABA (Doodeen daroogada sulfa kiimikada) iyo diethylaminoethanol (isagoo talaabo vasodilating dhexdhexaad ah). Soo bandhigay in kelyaha ee foomka of metabolites.

The Halabuurka iyo qaab "Novocaine" daroogada

daroogada saaray sidii xal la isku duro waa a, dareere midab cad, in ampoules mugga 1 ilaa 20ml. Boqolkiiba firfircoon dhexdeeda waa 0,25 iyo 0,5. Intaa waxaa dheer, hal iyo laba-boqolkiiba sii daayo "Novocaine" Xalka diyaarinta. Qiimaha foomkan ku saabsan tahay 15 rubles.

Popular iyo budada, iyo sidoo kale xal Nadiif ah medicament, ku shubtay galay fijaan ee 0.2 iyo 0.4 litir. Waayo, daawaynta cudurada badan codsan cadar 5 iyo 10 boqolkiiba, iyo dabada, kuwaas oo ka kooban 0.1 grams oo firfircoon (hydrochloride procaine), iyo sidoo kale qaybaha kaabayaal - witepsol ama Tællelyset. In 1 ml oo ah walaxda firfircoon ku jira qadarka 0,005 grams, qaybaha dheeraad ah u dhaqmaan aashito, iyo biyo la isku duro.

Tilmaamayaasha

Drug tilmaamaha "Novocaine" loo isticmaalo waxaa lagu dhiirigelinayaa inay soo magacaabaan si ay u qabtaan retrobulbar, terminal, laf-dhabarta, silig, epidural, suuxdinta dhexgalka. Isticmaalka vagosympathetic saarka medicament iyo go'doominta Annagaana ugsa dhaw perirenal. Codsiga of saboostada waa waxtar u leh Xanuun joojiyaha la dillaacyada futada iyo baabasiirka. Isticmaalka cadar sababa calaamadaha neurodermatitis, cambaarta, dermatosis cuncun.

Daawo "Novocaine": tilmaamaha loo isticmaalo

Cirbadaha bukaanada qaangaarka ah sida suuxdinta dhexgalka in mugga a of 300-600 mg (0.25-0.5 boqolkiiba xal).

Dhagan by gurguurta dhexgalka nidaamka Wisniewski waxaa la sameeyaa by bandhigid xal 0,25% ee lacagta ah ee 125 ml. suuxdinta Epidural waxaa loo sameeyaa iyadoo la kaashanayo "Novocaine" xal laba-boqolkiiba. guide irbado ku talinaysaa qiyaasta a of 25 ml. Suuxdinta laf-dhabarka laga heli by 2-3 ml of 5% daroogada. In dhaqanka ENT 10% of xal daroogada loo isticmaalo suuxinta la mariyo.

Si loo kordhiyo mudada uu garoomada ka mid ah daroogada iyo in la yareeyo ay absorbability, iyo sidoo kale at a suuxinta daroogada "Novocaine" maxaliga ah qasi jiray xal of hydrochloride epinephrine. Si aad u qabtaan electrophoresis ah waxaa lagula talinayaa in ay isticmaalaan 10% daroogada. Oo xaydha perirenal markii xanibaadda ee Wisniewski waa ka gala 60 ama 120 ml oo ah 0.5-th ama 0,25% xal, siday u kala horreeyaan. Go'doominta Vagosympathetic soo saaray by bandhigid 100 ml oo ah sheyga of 0,25%-fiirsashada.

In kasta oo sababo irbado carruurta "Novocaine" waxaa inta badan qoray sida xanuunka ah inta lagu guda jiro maamulka daawooyin kale. qiyaasta waxaa lagu saleeyaa miisaanka ilmaha (aan ka badnayn 15 milligram per kiilo).

dabada futada waxaa loo isticmaalaa ka dib markii purgation hore sameeyaa via enema ama si dabiici ah. Marka heley maqaarka cadar codsatay in ay daaha saameysey khafiifka daboolaa laba jeer garaacay.

waxyeellooyin

Drug "Novocaine" (tilmaamaha loo isticmaalo digo of this) waxay keeni kartaa falcelin xun.

Bartamaha iyo habdhiska durugsan jawaabaan madax daawo, daciifnimo, dawakhsanaan, dawakhaad, nasasho la'aan ah, qalal. Xaaladaha qaarkood, waxaa jira ay Cabsato, miyirka oo luma, daaman, maqalka iyo aragga, paraesthesia, curyaannimo lugaha, nystagmus. Intaa waxaa dheer, waxaa laga yaabaa in qallal neefsashada, is hortaagaan murqaha neefsashada.

nidaamka wadnaha-vascular waa isbeddel ku yimaadda cadaadiska dhiigga, waxaa jira xanuun xabadka, arrhythmia, bradycardia, burburkii, vasodilatation ka durugsan.

nidaamyada Urinary iyo dheefshiidka jawaabaan isticmaalka daawada la kaadinayo aan ikhtiyaarka lahayn, ku saxaroodaan, matag iyo lallabo.

On qayb ka mid ah nidaamka wareegga dhiigga si ay waxyeelo ka mid ah methemoglobinemia. Intaa waxaa dheer, daroogada waxay keeni kartaa dareen diidmo oo xasaasiyadeed:

• finan;
• anaphylaxis ;
• finan maqaarka ah,
• cuncun.

Waayo, dareen diidmo oo kale oo taban ka mid ah suuxinta joogto ah, kacsi, hypothermia, dhabar xanuunka. Inta lagu jiro suuxinta ee ilkaha arkay dheer ee suuxdinta, paresthesia iyo kabuubyo ah dibnaha iyo carrabka.

badinta

Si aad u isticmaasho ay "Novocaine" qoro daawada, taas oo muujinaysaa daawada waa in la dhakhtar soo qoray. Haddii la raaci waayo sharciyada laga yaabaa in calaamadaha xad dhaafka ah. Calaamadaha isticmaalka xad-dhaafka ah medicament waa doorsoonka ee xuubka oo integument maqaarka, methemoglobinemia, xibin gal, dhibic cadaadis lama filaan ah, tachycardia, neefta oo ku qabata, matag, dhidid qabow, lallabo, madax wareer. Bukaan-socodka waxay leeyihiin dareen cabsi, cadhoodaan motor, qalal, dhallanteed. Si aad u baabi'iyo daliilka badinta, lagama maarmaan ah si ay u fuliyaan hawo pulmonary la neefsado oxygen, xaaladaha adag, qori astaamaha iyo therapy naanin.

sababo

Isticmaalka daroogada ma laga yaabaa in dhammaan bukaanada. Marka habka suuxinta wuxuu mamnuucayaa wakiilka gurguurta dhexgalka isbedelada fibrotic unugyada. suuxdinta subarachnoid aan la fulin karo ee septicaemia ah, dalalka lama filaan ah, hypotension, dhiig-bax. Waxaa laguma talinayo in ay galaan daaweyn rasmi ahayn, tusaale ahaan, ka dhigi cadaadi ah oo leh "Novocaine".

Iyadoo diyaarinta taxaddar loo isticmaalo inta lagu jiro hawlgallada in bukaanka qaba dhiig la'aan ba'an, kelyaha, xaaladaha ku lug leh hoos u of qulqulka dhiigga, cagaarshowga, wadnaha sare iyo yaridu vascular, dul caabuqa ugu duray; heley bararka. Under kormeer caafimaad ee gaarka ah waa lagama maarmaan in la isticmaalo dawada xilliga dhalmada, bukaanka culus oo u jilcay, dadka waayeelka ah iyo carruurta ka yar da'da loo badanyahay.

Iyada oo daawada xinjirowga lidka weheliso ( "danaparoid" "Warfarin", "Ardeparin", "dalteparin", "Enoxaparin" "heparin") wuxuu kordhiyaa khatarta ah ee dhiig-bax. Hoos ka cadaadiska iyo bradycardia arkay inta lagu guda jiro maamulka isku mar daawo daawooyinka "trimetafan", "mecamylamine", "guanadrel", "guanethidine." Kordhi falalka daawada suuxinta lacag "epinephrine," "methoxamine", "Phenylephrine."

Features of codsiga

Ka hor inta milo "Novocaine" oo ay ka dhigi shot a, waxaa loo baahan yahay in ay daruuri tahay si loo ogaado dareenka shakhsi in daawooyinka. Si arrintan loo sameeyo, lagu fuliyo baaritaanka maqaarka ah, iyo haddii ay jiraan waa casaan iyo barar lagu xukumi karaa shaqsi aan aqbalo waxay ka dhigan tahay.

Inta lagu guda jiro daawaynta waxaa lagama maarmaan ah si ay ula socdaan hawlaha ka mid ah hababka wadnaha, habdhiska neefsashada iyo. Si loo yareeyo ku systemic gaadhista, sumoobo iyo in la kordhiyo saamaynta daroogada lagu jiro suuxinta maxalliga ah, daroogo "lidocaine" ama "Novocaine" waxaa loo isticmaalaa in lala vasoconstrictors. Waayo, kanu, hal dhibic oo xal hydrochloride epinephrine ayaa lagu daray 3 ml of medicament ah "Novocaine".

The more sare fiirsashada of xal loo isticmaalo, waa daroogada sun. Si loo yareeyo saamaynta ay ciidamada waxaa lagu talinayaa in la yareeyo qiyaasta guud ee medicament ama la badhxay in ay ka awood yar. Taas waxa loo sameeyaa iyada oo nadiif ah xal isotonic of chloride sodium.

Waayo, ka hortagga fal-celin diidmo ku jira marxaladaha hore ee daaweynta maamula a 2 ml laba-boqolkiiba xal, oo intii saddex maalmood ah (haddii ay jiraan waxyeelo ma laha) dose uu kordhay ilaa 3 mL, ka dibna soo baxa si ay u isticmaalaan mugga buuxa ka dib - 5 ml duro.

Inta lagu jiro daaweynta bukaan-socod ayaa loo baahan yahay in la siiyo ilaa wadista iyo fulinta waxqabadyada la xidhiidha dareenka korodhay, xawaaraha of motor iyo jawaab maskaxda.

Dhexgalka daroogooyinka kale

Marka intravenously maamula, daroogada wanaajisaa saamaynta inhibitory ku saabsan daawada dajiyaha habdhiska, kiniiniga hurdada, qalabka loo isticmaalo suuxinta guud, dejisa iyo analgesics maandooriyaha. Daawada dheeraada tallaabo ee muruqa, block dareemayaasha sababa suxamethonium. Halista hypotension waxaa kordhay isticmaalka wadajirka ah ee lacagaha "Novocaine" la MAO).

daroogada Anticholinesterase kordhin sumoobo ee daroogada, joogsada in ay hydrolysis. Para-aminobenzoic acid, taas oo metabolite ka mid ah daroogada, hoos saamaynta antimicrobial of sulfonamides, maxaa yeelay, iyagu raalli uga antagonist tartan. jaaniska of falcelinta maxaliga ah ee foomka of bararka iyo cudurrada kor u kacay irbado meel processing maamulka daawada suuxinta via xal jeermiska ka kooban macdanaha culus.

Isticmaalka "Novocaine" daroogada inta aad uurka leedahay

Inta lagu jiro iyo wallacaaga haween badan waxaa soo food leh daaweynta u baahan ilkaha ama calaamado kala duwan oo xun, sida dhabar xanuunka. In ilkaha, suuxinta loo isticmaalo inta badan macnaheedu yahay "Novocaine". Isticmaalka daroogada ee xaaladahaan waa la aqbali karo. Waxa kaliya ee aad u baahan tahay in aad dhakhtarkaaga ku saabsan uurka in uu daroogada la isticmaalay, iyada oo la tixgelinayo xaaladda taagan. Marka toxicosis, Socota la isbedel ku cadaadiska dhiigga, sida la ogol yahay daawo "Novocaine". In uurka, isticmaalkeeda ayaa suuragal ah keliya at cadaadis kacsantahay, ka dib markii la tashanaya ka hor inta aan la dhakhtarka.

Tool fududeeyaa shaqada wadnaha iyo saamaynta nasto on muruqyada. Marka aad aragtid calaamadaha xanuunka caloosha, kuwaas oo la xiriira cudurka boog ulcer, waxaan ku talinaynaa isticmaalka dabada. Caadi babaasiirta cadaadis sidoo kale suurto gal isticmaalaya dabada. Drug "Novocaine" waxaa loo isticmaalaa inta ay uurka leedahay oo keliya on qoro, is-daawo lama ogola! takhasuska xisaabi doonaa qiyaasta loo baahan yahay iyo inta jeer ee maamulka, ka dib markii la falanqeeyo tilmaamayaasha ee uurka. Dabada waxaa loo isticmaalaa laba jeer maalintii, pre-nadiifinta jirka ah via enema.

Price iyo daroogada analogues "Novocaine"

Qiimaha "Novocaine" diyaarinta (qiimaha kala duwanaan karaan wax yar farmasiyada shaqsi) ee fijaan (0.5%) waa 22 rubles. Per weelka xal 0,25% (200 ml) ama dabada futada siin doonaa 27 rubles. analogues Dhismayaasha oo ah walaxda firfircoon yihiin medicaments:

• "Hydrochloride Procaine".
• "Saldhig Novocain."
• "Novocaine-Vial".
• "Novocaine Bufus".