Daawada "Proksium": tilmaamaha loo isticmaalo, dhigooda dhabta ah

Sida loo isticmaalo daroogada "Proksium"? Tilmaamaha loogu isticmaalo daroogada waxaa lagu tilmaamay in qalabka maqaalka. In waxa aad ka heli doontaa macluumaad ku saabsan qaab kaas oo sheegay in medicament la sameeyo, haddii uu wax analogues, taas oo si loo magacaabay iyo wixii la mid ah.

Qaabka uu leeyahay, baakadaha, halabuurka ka mid ah daawooyinka

In waxa foomka waxaa la soo saaray waa daroogada ah sida "Proksium"? Tilmaamaha loogu isticmaalo jeedisay in daroogada taas waxaa laga heli karaa sida kiniin cad in baakad kartoonada, iyo sidoo kale lyophilizate la dhalada ee dareeraha (10 mL).

Foomka ugu horeysay ee daroogada laftiisa ka kooban pantoprazole a (40 mg), iyo sidoo kale waxyaabaha dheeraad ah. Marka la eego weelka lyophilizate, ka dibna waxa kale oo ka mid ah 40 mg ah ee firfircoon + hydroxide sodium.

Pharmacodynamics medicament

Waa maxay astaamaha uu leeyahay daawada "Proksium"? Tilmaamaha loogu isticmaalo ayaa tilmaamaya in this anti-boog iyo antisecretory wakiilada.

Ka dib markii qaadashada daroogada gudaha blocks waxaa soo saarka ee Aashito. Tani waxay dhacdaa iyada oo sababtu tahay anada tallaabada of proton ah si aad u codsato, waa in unugyada parenteral ee caloosha.

The walax daroogada firfircoon oo awood u leh yaraynta asalka iyo enzyme pentagastrin firfircoon, cunto iyo insulin, dheecaan gastric. Intaa waxaa dheer, daroogada uu hakiyo hawlaha muhiimka ah oo ka mid ah bakteeriyada Pylori Helicobacter. Sida la og yahay, waxa ay ka dhalmo firfircoon u yeelaan formation of boogaha iyo erosions ee xub-axaleedka derbiyada caloosha.

Waxa intaa dheer in kor ku xusan, loo arkaa daroogada kordhisaa tayada waxqabad ee wakiilada kale antimicrobial.

Pharmacokinetics daroogada

Waa maxay daawada wuxuu leeyahay sifooyin pharmacokinetic "Proksium"? Tilmaamaha loogu isticmaalo warrami bukaanjiifka oo ku saabsan xaqiiqada ah in ka dib marka ugu horeeysa ee saamaynta daroogada waa mid aad u deg deg ah horumarinta iyo socdaa maalmo.

content ugu sareeya ee daroogada ee plasma dhiigga arkay afar saacadood ka dib markii la helo qiyaasta caadiga ah ee 40 mg. Degree ee xigay la borotiinada waa 98%. Markii ugu bar-nolosha ee daroogada gaaro laba saacadood.

Dheefay daroogada iyada oo kelyaha iyo mindhicirrada.

Pantoprazole nuugo xiidmaha yar. bioavailability The oo ah walaxda waa qiyaastii 75%.

Dheef-daroogada qayb firfircoon ee beerka. Marka ay taasi dhacdo reaction conjugation ah, dealkylation iyo qayilo la qaybgalka tooska ah ee enzyme sida P450 cytochrome.

Sidoo kale waa in Waxaan la soco in daroogada loo tixgeliyaa si fudud u gudbo caqabad dhiig-maskaxda. Intaas waxaa sii dheer, waxa ay u taagan tahay soo baxay la caanaha hooyada.

In dadka waayeelka ah, fiirsashada plasma iyo bioavailability daroogada waa ka sii badan in bukaanka ka yar.

In joogitaanka daroogada cirrhosis lagu outputted kartaa ilaa 9 saacadood.

Marka ay maamusho?

Haddaba aad u ogaato sida daroogada "Proksium". Tilmaamaha loogu isticmaalo, dib u eegista ku saabsan daroogada soo jeedisay in muujinaya in ay si loogu isticmaalo waxaa ka mid ah cudurada soo socda:

• boogaha caloosha iyo 12 boog dyspepsia (oo ay ku jiraan xilliyo sii daridda);
• daaweynta bakteeriyada Helicobacter Pylori (aqbali kaliya qayb ka mid ah therapy adag);
• esophagitis reflux iyo Zollinger-Ellison syndrome,
• wax soo saarka kor u kacay oo casiir gastric;
• foomka khafiif ah esophagitis reflux.

Ma codsan kartid

sababo kasta oo uu leeyahay daroogada sida "Proksium" (kiniin)? Tilmaamaha loogu isticmaalo warrami bukaanka in foomkan of daroogada kiis kasta waa in aan la qoro haddii:

• failure cagaarshowga, oo daran;
• uurka;
• carcinogenic in xubnaha of mareenka caloosha iyo mindhicirka,
• naas-nuujinta,
• xasaasiyad in qaybaha daawooyinka,
• carruurta ka yar 14 sano.

Marka la eego xal ee fijaan, waxaa laguma talinayo dadka qaba dareen diidmo oo xasaasiyadeed in "Pantoprazole". Intaa waxaa dheer, foomkan daawada ay dhacdo in kasta oo aan lagu dari karaa ka "ATV".

Kiniiniga "Proksium": tilmaamaha loo isticmaalo

Analogs daroogada anti-boog la soo bandhigi doonaa dhamaadka maqaalka. Qaybtaan, waxaan kuu sheegi doonaa saabsan sida daroogada this waa in la hoos cuduro gaar ah.

In magacaabista daroogada "Proksium" dhakhaatiirta ugu doorbiday qaab kiniin ah. Haddii bukaan-socodka ku adag liqidda, xal ka dibna wuxuu ku soo qoray.

qiyaasta of daroogada, iyo sidoo kale hab hesho waa in la go'aamiyo dhakhtarkaaga kaliya.

Sidaas daraaddeed sida loo qaato daawada "Proksium 40"? Waxbarashada (kiniin suuq ka dhigan tahay in dhammaan farmashiyayaasha) dhigayaa in qiyaasta lagula taliyey of daroogada waa 40 mg maalintii. daroogada la qaatay inta lagu jiro ama ka dib markaad cunto, la cabo biyo fara badan.

Marka ogaado boog gastric ama nabaad dose maalin walba kordhay ilaa 80 mg.

Wixii lagu daaweyn jiray 12 daawo boog dyspepsia qaato 15-30 maalmood. Sida esophagitis reflux, iyo boogaha gastric, daawaynta cudurada sida waa in wax ka badan 2 bilood.

Si aad u baabi'iyo bakteeriyada Helicobacter Pylori bukaanka 1 kaniini laba jeer maalintii. Muddada aad daawada tani waa 2 todobaad.

Bukaan la taahaya kelyaha, iyo sidoo kale dadka waayeelka ah qiyaasta maalin aan la maamulo ka badan 40 mg.

Marka beerka iyo daawo beerka cirrhosis daran waxaa loo ogol yahay in ay qaataan 1 kaniini maalin kale oo kasta.

Xalka "Proksium": tilmaamaha loo isticmaalo

The ampoules diyaarinta sida loo qoro ee maamulka afka wax aan macquul aheyn.

Galay weelka ay ku jiraan lyophilisate waxaa ku shubtay galay 10 ml of xal jirka ah. Khubarada qaarkood waxay ku taliyaan daroogada noocan oo kale ah waa dheeraad ah lagu daray, 100 ml oo ah 5% xal glucose.

faleebo xididka waa in ugu yaraan laba daqiiqadood (doorbidayaa ku saabsan ¼ saac).

xal daroogada waa in la isticmaalaa isla markiiba ka dib markii la xidhiidha dhammaan qaybaha. Haddii ay taasi looma baahna, ka dibna daroogada waa in lagu rakibaa qowlad qaboojinta iyo codsan aan ka dambayn 12 saacadood.

Muddada daaweynta kiniin la mid ah si medicament. waqtiga ugu badan ee daaweynta - 2 bilood.

In cudurka sida esophagitis reflux, daroogada waxaa maamula qadarkuu of hal dhalo maalin kasta.

Wixii lagu daaweyn jiray dhiig dhacay boog 12 kansarka ah boog iyo caloosha dyspepsia iyo sidoo kale ka hortagga labakaclaynta, daroogada waxaa loo isticmaalaa 80 ml of intravenously (bolusdose).

Hordhac of infusomats daroogada muujiyey this isticmaalaya 8 mg saacadiiba.

Marka Zollinger-Ellison syndrome iyo medicament hypersecretion qoray 80 mg. dhakhtarka kordhin kartaa qiyaasta ilaa 160 mg haddii loo baahdo. Xaaladdan oo kale, waxaa looga baahan yahay inay kala qaybi 2 qaadasho.

Si deg deg ah loo yareeyo ashitada casiir gastric, sida caadiga ah la isticmaalayo 80 mg ah ee daawada laba jeer maalintii.

xaaladood oo badinta

Waa maxay calaamadaha yimaadda marka qaadasho sare "Proksium" daroogada (40 mg)? Buugga ayaa sheegay in xaaladaha la joogo sida ay jiraan farriimo lahayn.

Marka maamulo daawo intravenously (ugu badnaan 240 mg) waxaa dulqaadan si fiican. Haddii aad isticmaasho xaddi weyn oo daroogada, waxaa lagama maarmaan ah in aad dalbato dayactirka iyo therapy naanin.

Khubarada ayaa soo jeedinaya in badinta kiniinka "Proksium" kordhiyo xoog iyo inta jeer ee waxyeelo laga yaabaa. Xaaladdan oo kale, joojin qaadashada kiniinka.

dhibaato

Waa maxay saamaynta rabin dhici kara in bukaanlayda qaadato "Proksium 40" daroogada? Waxbarashada dhigayaa in isticmaalka qalab this inta badan keenta in:

• caloosha oo, xanuun caloosha, shuban iyo yaaqyaaqsi,
• cephalgia.

Mararka qaarkood, bukaanada laga yaabaa:

• cuncun iyo maqaarka finanka;
• matag,
• arthralgia;
• qallayl ee xub-axaleedka;
• kor u kacay rabitaanka cuntada,
• yarayn;
• Cudurka anjioedema,
• tabar iyo dawakhsanaan;
• wareer.

Sidoo kale, kiisaska oo ka mid ah cilladaha soo socda ayaa la soo sheegay:

• murugada, myalgia, Lyell syndrome, finan, Stevens-Johnson syndrome,
• hawlaha kor u of falgalka beerka, cagaarshow, hepatocytes burburay, qandho, kelyo xanuun,
• daata, iftiinka, Torombositobiiniya, leukopenia;
• thrombophlebitis (xiriira xalka dhacaa goobta la duray);
• gariirka, isku yaacsanaan, hoos u ah ee maqalka iyo aragga,
• finan, alopecia, hyperglycaemia.

isdhexgalka daroogada

Waa kuwee sifooyinka daroogada si uu bukaan-socodka in ay ogaadaan ka hor inta aadan qaadan daawada "Proksium"? tani waxay ka dhigan edbinta muujinaysaa sifooyinka soo socda:

• daawo viewed lagu dari karaa ka "Diclofenac" caffeine "Glibenclamide" ethanol "phenytoin", "metoprolol", "diazepam" "nifedipine", "carbamazepine" "theophylline", "digoxin" iyo wakiilada ka hortag oo hormoon "naproxen" iyo "digoxin".
• Waa aan loo baahnayn in la qaato qalab la "ATV".
• Daawada xinjirowga noocan oo kale ah waxaa coumarin sida "phenprocoumon" iyo "Warfarin" isku dhafan oo "Proksiumom" keeni karta in hoos u dhac in mawqif.
• No Caafimaad isdhexgalka daroogada la "metronidazole", "amoxycillin" iyo "clarithromycin" weyn loo aqoonsaday.
• Pantoprazole yaraynaysaa absorbability daroogada, bioavailability ah kuwaas oo si toos ah saamaysaa qiimaha pH oo casiir ah gastric ah (tusaale ahaan, "Posaconazole", "ketokonazol" "Itraconazole" "Atazanavir", "Erlotinib").
• Isku darka leh medicament ah loo tixgeliyaa "MTX" inta badan keenta in la kordhiyo in sumoobo dambe.

talooyin gaar ah

Waa kuwee sifooyinka of daroogada waa in la wargeliyo takhtarka ka hor inta aadan ku meelayn daawada bukaan sida "Proksium" (kiniin)? Shuruucda LABAGEEDI OO in medicament, reading this loo baahan yahay. Waxa uu sheegay in daroogada waxaa ka mamnuuc ah in ay qaataan dadka qaba dyspepsia dareemayaasha.

Marka la helo daroogada muddo ka badan saddex bilood, bukaanka waxaa laga yaabaa in la horumariyo hypomagnesemia. Calaamadaha cudurkan waa: Qabqabashada, daal, tetany, delirium, wareer iyo ventricular arrhythmia. Haddii ay dhacdo in calaamadaha sida daawada waa in la baabiiyo oo isla markiiba la tasho dhakhtarkaaga.

Ka hor inta daaweynta iyo ka dib gastroendoscope xiritaanka ay daruuri qaadeen si loo ogaado gobolka xiidmaha. Waa in la dhasha maskaxda ku haysaa in pantoprazole noqon karaan kuwo ay fududahay in la hoosaasin calaamado kansar.

Qiyaasta ugu badnaan maalintii dadka waayeelka ah iyo dadka bukaanka ah ee qaba cudurka kelyaha ee 40 mg. Waayo, bukaanka qaba cirrhosis lacagta maalinlaha ah ee daawada in la dhimay by badh.

heshiisyo Therapy la tahay, marmar dhif ah, waxay keeni horumarinta campylobacteriosis iyo salmonellosis.

inhibitors proton pump kordhiyaan halista jab lafta ee dadka waayeelka ah by saabsan 30% (muddada fog-daweynta).

Analogs iyo micne ah daroogada

Haddaba aad u ogaato waxa uu yahay iyo sida loo qaato daawada "Proksium". isticmaalka hab this ee edbinta ayaa la tilmaamay in si faahfaahsan kor ku xusan.

Haddii sabab kasta daroogada ma kugu habboon, waxaa lagu beddeli karaa by dhigooda caadiga ah, sida "Barolo", "Emanera", "Geerdin", "esomeprazole", "Diaprazol", "Ortanol", "Nexium", " rabeprazole, "" Veloz "," Sanpraz "," lansoprazole "," Ezolong "," Gasek "," Ultop "," Deksilant "" Pariet "," Zulbeks "," omeprazole "," Omelik "," Ozol " "Losek", "Omez", "EBikuras", "Omealoks".

Sidoo kale, daroogada "Proksium" waxaa loola jeedaa, waxaa jira daawooyin-micne ah "Kontrolok", "Pantazi", "Panzol", "Panum", "Nolpaza", "Penta", "Pantex", "Pultset", "Ultera".

Reviews of medicament

Shiidaa oo dhan dib u eegista daawada waxaa loo tixgeliyaa wanaagsan. Bukaan-socodka waxay ku andacoodaan in daroogada "Proksium" horumarinaya bogsashada deg deg ah ee erosions iyo boogaha, iyo sidoo kale looga hortago horumarinta ee soo noqoshada.

Sida waxyeellooyin, bukaannada inta badan muujiyey waxaa ka mid ah lalabo iyo dhibaatooyinka la kursi.