Daawada "Singlon": tilmaamaha loo isticmaalo, dhabta ah

nin Modern naftiisa oo dhan ku weheliyay arrimo taban sida stress soo noqnoqda, nafaqo xumo, xaaladaha deegaanka saboolka ah. Haddii dad caafimaad qaba waxay u badan tahay si ay ula qabsadaan saamaynta xun ee mid kasta oo iyaga si gaar ah, saamaynta ay isku mar ah oo dhan oo iyaga ka mid ah waa ay awoodaan in ay keeni badan oo aadanaha cudurada oo adag, taas oo dhib weyn in lagu daweeyo. Laakiin waxaa jira qaar ka mid ah cudurada for daawo dhameystiran kaas oo daawo-teknoolojiyad sare oo casri ah ayaa weli ma aasaasay daawooyin wax ku ool ah. Tusaale ahaan A duwanyihiin of this "silica aadanaha" - neefta. Iyadoo la tixgelinayo in cudurkan la hadli kartaa oo ku saabsan jiritaanka daawooyinka loogu talagalay therapy wanaajinaya tayada nolosha iyo ka-hortagga. Mid ka mid ah daroogada oo kale waa "Singlon".

In laxanka ee neefsashada

Guud ahaan, neefta bronki - nooc ka mid ah xasaasiyad ka kooban qaar ka mid ah deegaanka aadanaha. cudurka waxaa ku weheliyay dadka tan iyo wakhtiyadii hore. badan oo ka mid ah nin, ka cabanaya cudurka sida, wuxuu ahaa la mahdin. Kaliya ee qarnigii 20aad, markii dadku bilaabay inay horumariyaan aqoonta berrinkii xasaasiyad, ka dibna waxaa loo waxyooday xiriirka ka mid ah cadaanyo iyo neefta.

daawo Modern oo lagu daweeyo neefta bronki isticmaalaa laba nooc oo ah daroogada. marka hore waxaa ka mid ah daawooyinka aasaasiga ah therapy oo saamayn hab ay cudurka iyo samaynta suurto gal tahay in la xakameeyo ay socodka, si loo yareeyo khatarta weeraro. kooxda labaad ee daroogada - waa daroogada calaamadaha, kuwaas oo ugu muhiimsan ujeedada - cupping. Baahida loo qabo daawooyinka ka mid ah kooxda labaad waxa loo arki karaa iney yihiin tilmaame of tayada daaweynta caafimaadka: wanaagsan xarunta doortay aasaasiga ah, kan yar waxaa loo baahan yahay codsiga ah ee daroogada astaamaha.

"Singlon" allergies (neefta bronki - nooc ka mid ah xasaasiyadda) khubaro loo xilsaaray sida kale ah ama daawo dheeraad ah kiisas bukaanka xanuunka neefta khafiif ama dhexdhexaad ah saxariirinta. Sidoo kale, daroogada this dhakhtar bedeli karaa qiyaas yar corticosteroids in bukaanka qaba neef fudud.

Tilmaamayaasha loo isticmaalo

gudbikaraa ugu weyn ee saamayn "Singlona" - neefta. Waxaa intaa dheer, khubaro ku talinaynaa qaadashada daroogada ee koorsada dabcan daaweynta, iyo dembidhaafka. Intaa waxaa dheer, daroogada ahaan loogu talo galay dadka ay dhibaatadu ka diidmo ama dulqaad in la sameeyo si ay u acetylsalicylic acid ( "aspirin" asthma). daroogada waxtar u leh ka hortaga dadaal jireed bronchospasm.

Sida an therapy "Singlon" edbinta dheeraad ah waxaa loo isticmaali karaa in kiisaska cudurka neefta joogto ah (darnaanta - iftiinka iyo mid dhexdhexaad ah) waxa ay gacanta ku macnaheedu yahay gargaarka degdegga hawlqabad la'aan sida, sida corticosteroids neefsado iyo β-agonister gaaban.

Nuxurka oo ka mid ah "shaqada" ee daroogada waa in ay tahay waa ay xakameyn karaan bronchospasm by yareynta hawlaha ee peristalsis hawomareenno, oon ku gaari kara yaraynta suuraggalnimada horumarinta weerarka. In kasta oo xaqiiqda ah in la nuugo "Singlon" (oo la mid ah in ay dhaqanka ee arrintan la xiriira in siyaabo kala duwan) si deg deg ah oo ku filan, waxay waxaa loo arkaa daawo dheer-simaha. Si fudud u gelin, ay u shaqayso iyo buuxiyo ay "waajib" ee jirka aadanaha saacado badan.

The Halabuurka iyo foomka jira sii daayo

Diyaarinta "Singlon" macmalay by saarayaasha qaab kiniin la calaashado. The qayb firfircoon ugu weyn - montelukast sodium. Sida qaybaha kaabayaal taag mannitol, milmahayn magnesium, aspartame, giproloza. Intaas waxaa sii dheer, in ay "Singlona" waa iidaan cherry.

The kiniin medicament dahaarka leh waxaa lagu sameeyey wareegsan, biconvex. Available saddex qaadashada. Bukaanka 15 sano jir ama ka weyn dose loo baahan yahay ee medicament "Singlon" - 10 mg. Tilmaamaha qof oo qaba neef, dejisa maalin dhamaadka maalinta in ay qaataan 1 calaashado qiyaasta kiniin oo ah 10 mg (cuntada ka hor ama ka dib - daryeelka). Si kastaba ha ahaatee, mararka qaarkood, waxaa laga yaabaa in dhakhtar kuu qoro sida qiyaasta maalinlaha ah iyo 2 kaniini.

Sidoo kale, saarayaasha soo saaro daroogada ah ee qiyaasta a of 4 mg iyo 5 mg. Joogitaanka daroogada ee qaadasho ogolaanaya isticmaalka "Singlon" ee carruurta. Ilmaha 2 ilaa 5 sano qoray dhaweynta kiniin la calaashado at dose oo ah 4 mg. Waayo, daaweynta iyo ka hortaga exacerbations neefta carruurta waaweyn (6 ilaa 14 sano) waa in ay qaataan daawada ee qiyaasta a of 5 mg. Standard therapy caafimaad kiniin circuit labada qiyaasood (4 mg iyo 5) - mar fiidkii 1 saac cuntada ka hor, ama ka dib markii 2 saac cuntada ka dib.

kooxda reactions macquulka ah

Asal ahaan, daawada "Singlon" dib u eegista uu leeyahay jihada wanaagsan. Si kastaba ha ahaatee, bukaanka dhallinyarada ah iyo waalidka ay sheegeen in mararka qaarkood waxaa jira dhibaatooyin soo raaca daawooyinka, kuwaas oo muujiyay in lallabo iyo matag fudud, afka oo qalala, roonaadaan transient ee neefsashada. Khubarada tixraac noocan oo kale ah ka muuqan of falcelinta ee u shaqeeyo inuu la qabsado "ayuu Singlonu". Sida caadiga ah ka dib markii 3-4 maalmood ka dib bilowgii calaamadahan oo dhan baaba'aan.

shaqaalaha caafimaadka odhan macquul ah ku filan sare ee horumarinta dhacdada aan loo kasin dheeraad ah oo adag. Kordhinta u janjeera in la horumariyo dhiig muujin kartaa nidaamka durey iyo wareegga dhiigga. Ujeedo in uu anaphylaxis, diidmo, dhexgalka eosinophilic beerka - kuwanu waa dareen diidmo oo suurto gal ah in daroogada ay nidaamka difaaca jirka. eosinophilia systemic mararka qaarkood waxaa la socon kara by daliilka vaskulitis, iyo Churg-Strauss syndrome.

Waxaa laga yaabaa in qaar ka mid ah fogaanta dhexdeena ka yimaada habdhiska dhimirka ah, kuwaas oo ku dhici kara hurdo xumo, dhalanteed muuqaalka, kordhay dhaqdhaqaaqa psychomotor (caro, welwel, gardarada, gariirka). Kiniiniga kicinayaa "Singlon" (dib u eegista macaamiisha xaqiijin), murugada iyo hurdo la'aan. habka dareemayaasha jirka laftiisa sheegi karaan muuqaalka kore ee madax xanuun, wareer, paresthesia (kabuubyo, biinanka, iyo jidhidhico oo dubka, jiririco), dhacdo ka mid ah qalal. Sinaansho ee CCC ku muujin karaa sida tachycardia.

nidaamka dheefshiidka, sida hore u soo sheegnay, muujin kartaa jawaabta codsiga ah "Singlona" sida lallabo, matag, shuban, calool xanuun, afka oo qalala. reaction A oo ka mid ah maqaarka iyo baruurta subcutaneous laga yaabaa in u janjeera in ay nabar, finan, pruritus, urtikaria. unugyo iyo nidaamka muruqyada isu sheegi arthralgia (xanuun wadajir ah "kacsan" ay ka maqan yihiin calaamadaha Ujeedada burburka wadajir ah), myalgia (muruq xanuun).

Notes si daroogada "Singlon" edbinta iyo xaqiiqda ah in waxyeelo waxaa laga yaabaa in dabiiciga ah ee aan caadi ahayn caadi ah: qidmeyntii, daal, harraad, barar.

Aad iyo aad u saamaynta dose suurto gal ugu badnaan

Xaaladaha intooda badan loo yaqaan xirfadlayaasha caafimaadka "Singlon" badinta daroogada ma si gaar ah saameyn khatar ah oo aan la muujiyey. Koox yar oo bukaanka qiyaasta sii badnayeen ee montelukast - qayb ugu weyn ee firfircoon - sababay cadaanyo qaab calool xanuun, madax xanuun, harraad, lalabo, xaaladda fawdada ah. Ma jiro macluumaad haddii daroogada la raaca habka kelyaha sifeeya ah. Ma jiraan wax xog gaar ah oo ku saabsan daaweynta ah qiyaasta xad dhaafka ah ee montelukast. Sidoo kale waxaa jira daawo lahayn.

Haddii sabab uun la oggol ugu badan ee loogu talagalay la helo qiyaasta ayaa la dhaafo oo waxyeellooyin muuqata, bukaanka waa in lagu maamulo daaweynta calaamadaha.

Sababo in daroogada

Contraindication u helo medicament adeegta diidmo ama idiosyncrasy montelukast bukaan - qayb ugu weyn ee diyaarinta "Singlon". Halabuurka The oo ka mid ah qaybaha kaabayaal ah ayaa sidoo kale waxay sababi kartaa in bukaanka wacyi xanuunada daran ee caafimaadka. Tilmaamaha loogu isticmaalo si adag madnuucayaa qaadashada daroogada ee dadka qaba beer xanuun daran, phenylketonuria (-shiid daciif ah ee acids amino, inta badan phenylalanine).

"Singlon" (4 mg) edbinta mamnuucayaa caruurta ilaa laba sano. isticmaalka impermissible daroogada at dose of 5 mg carruurta jirta ilaa 6 sano. Well iyo, sida, inuu ku meeleeyo qiyaasta ugu weyn ee medicament "Singlon" (10 mg) edbinta ma ogola in caruurta ka yar 15 sano.

Isticmaalka daawada: tilmaamo guud

Saamaynta daweynta of daroogada "Singlon" (user, ratings bukaanka loo dhan yahay) waxaa 24 saacadood ka dib codsiga. Sida laga soo xigtay tilmaamaha of xirfadlayaasha caafimaadka si ay u qaataan daawooyinka dadku u baahan yihiin ma aha oo kaliya inta lagu guda jiro gacanta, socodka deggan xiiqda, laakiin sidoo kale in marxaladda ba'an. Waayo, bukaanka ka cabanaya la'aan cagaarshowga (fudud iyo kuwa dhexdhexaadka), yaridu kelyaha uma baahna saxo raan. Warbixin ku saabsan qof oo la silcayey beerka maqan daran.

Qiyaasta loo baahan yahay ee "Singlona" ma ku xiran tahay jinsiga qofka. Waxa aan la aqbali karin in ay qaataan daawada isku mar la qaar ka mid ah daawooyinka dheeraad ah kuwaas oo ugu muhiimsan ee qayb firfircoon - montelukast. Haddii sida therapy ah kabid daawada waxaa loo doortay inuu hore u heshay corticosteroids neefsado (glucocorticosteroids), maratay aan loo baahnayn in la beddelayo "Singlon". Iyo guud ahaan, daroogada this waa in aan bedelo corticosteroids kale neefsado iyo afka.

qiyaasta kiniinka la calaashado 4 mg (sida "Singlon" 5 mg), edbinta talinayaa sida tuubooyinka kale medicament neefsado isticmaalo in lagu daaweeyo xiiqda fudud. Isla mar ahaantaana "Singlon" qaabab kale waa in aan loo isticmaalin maandooriye aasaasiga ah ee daaweynta neefta dhexdhexaad ah.

Iyadoo la tixgelinayo carruurta qaba neefta bronki khafiif ah, isticmaalka "Singlona" sida daawooyinka kale la ogol yahay oo keliya in Xaaladaha haddii bukaanka dhallinyarada ah ayaa dhawaan la arkay weeraro halis ah. waa Daartii iyo kuwa aan isticmaali kartaa corticosteroids neefsado. Haddii hal bil gudahood ku guuldareysatay inay gaaraan gacanta lagu qanci karo cudurka, waxaa lagama maarmaan ah in la tixgeliyo suurtagalnimada ee ay ka mid yihiin daroogada ah daawo dheeraad ah ama la beddelo xeeladaha daawaynta anti-bararka. Bukaan la taahaya neefta iyo ciidanka lagu daaweyn jiray noocyo kala duwan oo daroogo (oo ay ku jiraan "Singlon"), edbinta u baahan xilliyo baaro gacanta sharciyeed cudurka.

Waxaa muhiim ah in la xasuusto in "Singlon" looma isticmaalo in lagu daaweeyo weeraro ba'an.

Uurka iyo nuujinta

Research on isticmaalka montelukast in haweenka uurka leh oo aan lagu sameeyay. The-aragnimo suuq caalami ah, waxaa jira xaalado marka ilmaha ay hooyadood qaaday inta lagu jiro montelukast uurka - qayb ugu weyn ee "Singlon" diyaarinta (edbinta, dib u eegista ha ku talinaynaa) - waqti ka waqti lagu arkay cillado lagu dhasho Addinka. Si kastaba ha ahaatee, ka dib waxaa soo baxay in naagtii mar horay kaxaysay iyo daroogada kale oo lagu daweeyo neefta bronki. Sidaa darteed, iyadoo la hubo in ay ka hadlaan sababta-iyo-saamaynta xiriirka daliilka cilladaha sida iyo isticmaalka montelukast suurogal ahayn. Si kastaba ha ahaatee, ka hor inta aadan u yeelaan naag uur leh si loo daweeyo "Singlon" asthma, dhakhtarku waa in si taxadar leh loo qiimeeyo oo dhan khatarta hooyada iyo ilmaha labadaba.

Ma jiro macluumaad ku saabsan in montelukast u muuqataa in caanaha naaska. Sidaa darteed, halkan aad muhiim u tahay in laga fiirsado "lacagta - halista ku jira".

Sifooyinka pharmacokinetic daroogada

Ku lifaaqan "Singlon" daroogada hadal leeyahay geedi socod ku filan si degdeg ah nuugista of lacag. Celceliska bioavailability ka dib codsiga (eegin hadhuudhka ah) - 64%. The qayb firfircoon ugu weyn "Singlona" in ka badan 99% ku xidhan borotiin plasma. 24 saacadood ka dib markii la helo medicament ay fiirsashada dhammaan unugyada jirka waa ay yar tahay. Daawada waxaa si ballaadhan metabolized. Saamaynta of metabolites on saamayn yar ku daweyn of daroogada. 86% qiyaasta of daroogada waxaa raaca iyada oo mindhicirrada, share lug ku Digo kelyaha - ka yar 0.2%. Qiyaasta ugu badan ee ah "Singlona" iyo metabolites ay raaca in bile ah.

Opinion bukaanada, waalidiinta iyo dhakhaatiirta

neefta bronki - chronic iyo cudur adag hiddo goostay. waxaa Hayso gacanta ayaa suuragal ah keliya iyadoo la isticmaalayo alaabta caafimaad oo casri ah. Hawomareenno bukaanka sida mar walba ay diyaar u yihiin si ay u horumariyaan weerarka. Iyo sababta oo ah dadka si joogto ah hareereysan xasaasiyadda, ka dibna ay u baahan yihiin in si joogto ah codsan dawooyinka ka kooban glucocorticoids. walxahan waxay leeyihiin waxyeelo badan, taasoo keentay saynisyahano si ay u bilaabaan raadinaya hab casri ah oo daaweyn ah.

Montelukast - qayb ugu muhiimsan ee daroogada "Singlon" (dhigooda uu sidoo kale ku jira walax this) waxay yeelan karaan saamayn kala duwan oo ku saabsan caafimaadka bukaanka. Waalidka bukaanada dhallinyarada ah qiimaynta inta wanaagsan ee daroogada sida therapy ah adjunctive. Haddii, ilaa dhawaan, daroogada this waa kala iibsaday ayaa laga yaabaa, laakiin hadda daawada waxaa laga heli karaa in dadka deggan Ruushka. Iyo qiimaha jaban tahay ka baxsan Russia. Waxaa laga yaabaa in magacaabidda carruurta yaryar laga bilaabo 2 sano jir: "Singlon" 4 edbinta mg u ogolaanaya in ay qaataan for daaweynta calaamadaha of kids. mudada qiyaasta aad u sahlan - 1 jeer maalintii, la doorbidayo fiidkii. Codsiga, oo ay la socdaan diyaarinta saldhig iyo sidoo kale-doortay ogolaanaya in kiisas badan si looga fogaado horumarinta neefta muddo dheer.

Dad badan ayaa la yaabi haddii ay daawada dhigooda "Singlon". Daawooyinka la qayb ka mid ah oo firfircoon (montelukast) suuqa dawooyinka ay jiraan wax badan ilaa xad ah. Waxaa ka mid ah daawooyinka sida 'Singulair' iyo 'Singuleks "," Montelast "iyo" montelukast "," Montelar "iyo" Monaks ". All of saarayaasha waxay bixiyaan daawooyinka bukaanada ee qaadashada badan. Ku dhowaad dhammaan iyaga ka mid ah waxaa loo isticmaali karaa in caruurta.

Bukaan badan ayaa si fiican u jawaabaan daroogada sida qalab wax ku ool ah ka hortag. bukaan ku filan oo qaba neef in la qaato kiniin ka hor jimicsiga, iyo waxay u badan tahay in horumarinta weerar ee neefsashada, qufac ama bronchospasm in laga fogaadaa. Asal ahaan "Singlon" si fiican loo dulqaatay (marka laga reebo - montelukast idiosyncrasy).

Mararka qaarkood waalidiinta sheegaan in carruurta ee bilowga ah ee soo dhaweynta waxaa ka soo qeyb lallabo, matag, a yar yar, dareen of qallayl ee afka. Koox yar oo bukaanka lahaa neefta go'aysa. Khubaro allergists ku xidhaan kuwan calaamadaha jawaabta ah qabsiga daroogada. Xaaladaha intooda badan, 3-4 maalmood si ay u caafimaad caadi ah ka dib.

Si kastaba ha ahaatee, waqtiga waa la maqli karaa waqti ka waqti iyo in "Singlon" xanaajiyeen horumarinta waxyeellooyinka sida aragti cawlan, dhalanteed, gariirka ee addimada, dhibic fiiqan ee cadaadiska dhiigga. bukaanka Individual lahaa in ay joojiso qaadashada daroogada iyo talo ka allergist ah doondoonaan.

Laakiin xusuusnow: ma ku falaan naftooda is-soo magacaabi waayo, daaweynta ee neefta bronki kiniinka "Singlon". Waxbarashada qoray pre-booqo dhakhtar safaree qiyaasta saxda ah ee daawada iyo horumarinta qorshaha daaweynta.