"Izoket" bifbaafka: diiwaanka, dib u eegista, sharaxaada, analogues, qiimaha

Maanta, khubaro badan oo qori bukaanada vasodilator buufin "Izoket" prophylactically ama, haddii loo baahdo, cupping istaroog ah. daroogada waxay leedahay liiska ballaaran tilmaamo kala duwan. Waxaa si guul leh loo isticmaalo in lagu daaweeyo heley wadnaha, ay ka mid yihiin la dagaalanka xaaladaha ba'an.

Farmashiiste

Wakiilka firfircoon ee daroogada ka-kog lagu gartaa guryaha vasodilating iyo vasodilator fahmayaan. Isosorbide dinitrate wuxuu kobciyaa formation of xabagta nitrogen in u shaqeeyo iyo yaraynaysaa shuruudaha muruqa wadnaha of ogsijiin iyo tamarta, isla markaana hoos load ku on myocardium ah. Waa wax ku ool ah oo yaraynaysa cadaadiska ee wareegga pulmonary, hoos u dhaca dhiigga ku shubma Atrium saxda ah, yaraynaysaa xiisad derbiga ventricular wadnaha iyo hoos u cadaadiska diastolic iyo shaqada systolic in iyaga hagaajinta. daroogada waxay leedahay saameyn ah kuma laha inta jeer ee foosha qalbiga iyo Ballaariyay weelashii cerebral si fiican. Waxa kale oo ay kor u qaadi kara xididdada dhiigga ee Mater Duuraa ee maskaxda ah, Kuna keenaya xanuun madaxa. Means saamaynta on qaybin ah ee socodka dhiigga wadnaha ee meesha socodka dhiigga waa la dhimay. In CHD (wadne xanuunka) iyo angina ay sabab u tahay tallaabo ah ee daroogada ee bukaanka qaba fursad ay ku kordhiyaan layliga la ogolaan karo.

Buufin "Izoket" si degdeg ah nuugo guud ahaan xabka ee aagga afka, si saamaynta ay codsiga bilaabmaa 30 ilbiriqsi ka dib iyo wuxuu socdaa illaa 120 daqiiqo. Thanks to xawaaraha waxaa inta badan loo qoro bukaanka gargaarka degdegga ah ee xaaladaha ba'an.

Form sii daayo

Daawada waa xal cad, taas oo midab iyo ur khamriga. Waxaa imanaya laba nooc:

1. Buufin "Izoket" iyo qiyaasta sublingual. Iyadoo mid ka mid click on qaybiyaha waa la sii daayay oo ah qaab dhibco yaryar oo ah mid ka mid ah ay dose oo ka kooban 1.25 mg ee firfircoon - dinitrate isosorbide iyo xubno kaabayaal: ethanol iyo Macrogol 400. Halabuurka buufis ayaa freon ah, si kastaba ha ahaatee waxa ay la xidhiidhaa daawooyinka aan dhib lahayn deegaanka. Soo saaray dhalooyin hufan of 15 ml, buuxiyey oo ku yaal sanduuqa la qaybiyaha iyo tilmaamaha. Dhalada Glass 300 qasabno (dose), wuxuu kuu ogolaanayaa inaad si ay ula socdaan xaddiga daroogada iyo u bartaan bedelka hab wakhti.
2. Xalka qaab shancosbitaal loogu talagalay infusions. 1 ml ee diyaarinta this ku jira 1 mg ah element firfircoon ee dinitrate isosorbide iyo walxaha kaabayaal: chloride sodium, hydroxide sodium, biyo. Mid ka mid ah ku shubtay - 10 ml oo xal loogu talagalay galiyey. Available in baakad kartoonada of 10 xabbadood kasta.

Tilmaamayaasha

Buufin "Izoket" khubaro magacaabay weerarada stenokardicheskie nooc kasta iyo qiyaas ka hortag ah si ayna u dhicin. Waxaa sidoo kale lagu talinayaa in wadamada post-Wadnaxanuun, Wadnaxanuun myocardial in marxaladda ba'an, sii kordhaya dulqaad la IMS iyo therapy ee dabac halbowlaha wadnaha. Buufis "Izoket" si guul ah loo isticmaalo sida daroogada ah ee wadnaha ee ventricle bidix. Sida laga soo xigtay tilmaamaha, xoogga, waayo, faleebo waxaa loo qoray in bukaanka qaba heley sida nidaamka wadnaha iyo,

• angina deganayn dhaca xaalad preinfarction ama Wadnaxanuun myocardial hore;
• angina vasospastic;
• Wadnaxanuun myocardial foomka ba'an, ay keento failure ee ventricle bidix ee wadnaha;
• vasospasm coronary inta lagu jiro waxqabadyada qalliinka;
• wadnaha oo dhan;
• wadnaha ventricular bidix ba'an;
• barar sambabada.

Hababka isticmaalka buufis ah

diyaarinta A qaab buufis buufiyaa saabka afka bukaanka, ay sabab u tahay waxa si deg deg ah uu galo dhiigga. duro kasta waxay bixisaa hal dose qofku cuno. Tilmaamaha loogu isticmaalo waxaa loola jeedaa siyaabo kala duwan oo la isticmaalayo daroogada, waxayna ku xiran tahay calaamadaha.

Si cupping weerar stenokardicheskie hor stress soo socda jireed ama mid caadifadeed oo keeni kara ba'an, dib u Neefta, iyo bukaanka uu helo 1 ilaa 3 jeer dura 30 ilbiriqsi dhexeeya irbado. Kordhi qiyaasta aan takhasus kormeer mamnuuc.

In the case of sii daridda tuhunsan yahay wadnaha ama Wadnaxanuun myocardial, ba'an ka badan bukaanka uu helo 1 ilaa 3 qiyaasood oo gacanta adag ee garaaca wadnaha iyo cadaadiska dhiigga labadaba. Haddii horumar lahayn, markaas waa habka lagu celceliyo shan daqiiqo ka dib go'aanka ah dhakhtarka. In tobankii daqiiqo ee soo socda, xaaladda waa in xasilinta. Haddii kale, waxaad ku celin kartaa khalkhalgelinta mar kale iyada oo ay kormeerayaan dhakhtar.

Baaritaanka ka hor daaweynta cupping dabac coronary (waayo, sanka lagu ogaanayo ama daweynta) maamula bukaanka ah lagu duro 1-2. Marka baahida kacay qiyaasta soo celin karaa, laakiin waa keliya haddii beegyada uu gacanta wareegga dhiigga.

talooyin gaar ah loo isticmaalo ee buufis

Xaaladaha marka lagu buufiyo cusub waxaa laga codsadaa markii ugu horeysay, ama kadib qiyaasta ee la soo dhaafay in ka badan 24 saacadood, waxaa lagu talinayaa in si toos ah saxaafada ugu horeysay ee hawada, sababtoo ah ma ku jiri kara qiyaasta loo baahan yahay. Waayo qaadasho waafaqsan nebulizer edbinta si joogto ah u riixriixan oo ilaa ugu dambaysta, ka dibna la sii daayay. Inta lagu jiro isticmaalka la qaybiyaha dhalada buufis waa in ay ahaadaan upwardly iyo vertical. Ka taxaddar oo fogaado firidhka galay indhaha. Inta lagu jiro muddada daawaynta oo dhan waxay u baahan tahay gacanta joogta ah cadaadiska dhiigga (BP) iyo burburiyaha ECG. Qiimaha cadaadiska dhiigga waa in aanay noqon wax ka yar 100 mm Hg. Art. bixitaanka kadis ah barashada daroogada mamnuucday, si qiyaas la ballamay hoos si tartiib tartiib ah. cabitaanka khamriga aan la talinayaa inta aad qaadanaysid buufis "Izoket".

xirfadlayaasha Reviews ayaa tilmaamaya in qiyaasta sare ee daawada, inta badan waa ballan ama isticmaalka nidaamsan u horseedi karaa horumarinta dulqaad in bukaanka. feature noocan oo kale ah oo horumarsan iyo isticmaalka daawooyinka kale ee ka kooban yihiin Nitrate. Xaaladaha noocaas ah, dhakhaatiirta ku talinaynaa in ay baajiso isticmaalka daroogada 2-3 maalmood, iyo ka dib markii koorso of daaweyn joogto ah, kaas oo socday muddo 3-6 toddobaad, ka nasto 3-5 maalmood, iyo waxa ay si ku meel gaar bedelo by daroogada kale oo saameyn la mid ah. Xaaladaha intooda badan, ka dib markii la dhexgelin dareen ama joojiyo bukaanka ah si deg deg ah halkii soo celiyo. ka dhigan tahay qaybaha soo jeeda metabolites sida kelyaha dhow buuxa.

Qiyaasta iyo codsiga xal

Sida laga soo xigtay shuruudaha diyaarinta waxbarashada "Izoket" (xal faleebo) waxaa intravenously codsatay. qiyaasta of vrechom daweynta si gaar ah loogu talo galay in ay ku hemodynamic iyo xuduudaheedu caafimaad ee bukaan-socodka. Therapy waa in ay bilaabaan la dose hooseeyo iyo kordhinta si tartiib tartiib ah ugu soo celiyaan lacagta loo baahan yahay. Tilmaamaha lagu talinayaa in qiyaasta waa 2-7 mg / hr, siday u kala horreeyaan, qiyaasta celceliska wuxuu ku saabsan yahay 7.5 mg / hr. Xaaladaha of mugga lagama maarmaan u daran waa la kordhin karaa ilaa 10 mg / hr.

Xaaladaha intooda badan, dadka qaba wadnaha waxay u baahan yihiin qaadasho sare ee daroogada. hordhaca ah ee daroogada waa mari daaweynta bukaan-jiifka iyada oo ay kormeerayaan takhasus ah iyo isticmaalka nidaamka si toos ah loogu talagalay galiyey. nidaamka oo dhan waxaa ku weheliyay tilmaamayaasha gacanta wareegga (cadaadiska dhiigga iyo garaaca wadnaha).

Xalka maamulka xididka loo diyaariyey xaaladaha sterile isla markiiba ka hor howlqabadka. Daawada waxaa aan ku kaydsan wax ka badan 24 saacadood. hababka diyaarinta:

• si uruuray of 0.01% (100 micrograms / ml) - 50 ml of 0.1% daawada laga yaabaa in 500 ml oo ah diyaarinta diyaar u ah maamulka,
• si uruuray of 0.02% (200 micrograms / ml) - 100 ml oo xal 0.1% ee daroogada soo saari kartaa 500 ml oo ah medicament ah oo diyaar u ah maamulka.

Sababo iyo tallaabooyin taxaddar ah

Daawada waxaa aan tilmaamay ee bukaanada xasaasiyad in ay xeryahooda amooniyam, iyo sidoo kale xubno kale oo ka mid buufis ah "Izoket". Codsiga waxaa sidoo kale mamnuuc ah haddii bukaanka cudurada sida:

• summer, at taas oo cadaadiska systolic ka hooseeyo 90 mm Hg.;
• kaafi vascular in marxaladda ba'an, tus, inta lagu guda jiro lama filaan ah ama vascular burburkii;
• pericarditis iyo tamponade pericardial;
• in si lama filaan ah cardiogenic xaaladaha halkaas oo ma jiro wax fursad si ay ula qabsadaan cadaadis si kale in ventricle bidix ee wadnaha;
• cardiomyopathy hypertrophic;
• glaucoma xidho.

Intaa waxaa dheer, daroogada aan tilmaamay ee dadka ka yar siddeed iyo toban sano jir. Tilmaamaha loogu isticmaalo talinaysaa isticmaalka daroogada si taxadir leh aad u badan iyo iyada oo ay kormeerayaan joogto ah xaaladaha sida:

• Wadnaxanuun myocardial la socodka ba'an marka bukaanka ayaa cadaadiska hoos u tagay buux wadnaha ventricle;
• kordhay cadaadiska intracranial;
• mitral iyo / ama stenosis aortic;
• garashadiisa itimaalka dhacdo ka mid ah xanuunada orthostatic bukaanka ee sharciyeynta wareegga dhiigga,
• kelyaha ama beerka.

Uurka iyo nuujinta

Seynisyahanno in horumarinta waxbarashada xoolaha daroogada ayaa la sameeyay. Tijaabada on imtixaanka muujisay in saamaynta waxyeello on uurjiifka lama sameeyo. Si kastaba ha ahaatee, inta lagu jiro xilliga uurka iyo nuujinta magacaabidda buufis ahaan waxaa lagula talinayaa oo keliya in kuwa xaaladaha faa'iidooyinka loogu tala galay in haweenka ay noqon doontaa si weyn u sii weyn tahay khatarta ka iman karta in ilmaha caloosha ama naas-ilmaha. Daaweynta xaaladaha ahaan waa iyada oo ay kormeerayaan adag ee xirfadlayaasha, oo xuduudaheedu gacanta wareegga (cadaadiska dhiigga iyo heerka garaaca wadnaha), iyo sidoo kale xaaladda guud ee bukaan-socodka.

Dhexgalka daroogooyinka kale

Waa mamnuuc in ay wadaagaan vasodilators iyo "Izoket" diyaarinta (buufis). Ay u isticmaalaan lagu daro keeni kordhin karaa saamayn hypotensive. saameyn la mid ah waxaa weeyaan dhaweynta wadajira "Izoket" iyo daawo buufis sida: antihypertensives, blockers calcium channel, "Quinidine" ama "novokainamid" neuroleptics, inhibitors 5-phosphodiesterase.

Xoogeysaneyso saamayn antianginal marka loo isticmaalo sida "Amiodarone", "propranolol", "Nifedipine", "Verapamil," iyo blockers kale ee calcium channel gaabiska lala daroogada.

cadaadiska intracranial kordhay bukaan dhici kartaa inta lagu jiro therapy isku dhafan oo atropine oo kale m-holinoblokatorami.

hoos u dhac xad dhaafka ah ee dhiig-karka, taasoo keentay in perfusion wadnaha, u muuqataa sarkhaansan Alfa-blockers iyo sympathomimetic.

Dhibaatooyinka ay keento iyo dib u eegis

The tilmaamaha ku tilmaamay in wax badan oo waxyeelo ee uu keeni karo by daroogada "Izoket" (buufis). Reviews bukaanada qaar lagu daaweeyaa daroogada this, ayaa muujinaya muuqaalka kore ee madax xanuun, taas oo dawo loo yaqaan "Nitrate". Sida caadiga ah, 2-3 maalmood ka dib markii dhibaatada baaba'aa u gaar ah oo aan u baahnayn saxo. Saas ma aha dhif medicament keeni karaa ifafaale ah sida lalabo, guduudasho ee maqaarka, matag, iyo afka oo qalala. Bukaanjiifka qaar ayaa helay daawada markii ugu horeysay, ka cabanaya tabar guud, dawakhaad, hoos u cadaadiska dhiigga iyo dareen feejignaan xumo. Tani waxaa sababa rabshooyin yar oo ku shaqaynaya nidaamka wadnaha iyo. Inay soo sara kacaan marka la isticmaalayo hoose ama qiyaasta lagula taliyey.

Si kastaba ha ahaatee, sida ay dib u eegid, bukaanka aragto iyo oggolyahay. Oo markii la helo iyada oo la raacayo shuruudaha xirfadeed ee waxyeelo ma dhacdo si joogto ah. marka laga reebo waa madax ka maalmood ee ugu horreeya ee la isticmaalo, taas oo uu weheliyo, intooda badan, laakiin inta badan maraa in dhowr maalmood.

Aad iyo aad u mug ugu badnaan

badinta daroogada waxay keeni kartaa dhowr ah oo leexashooyinkaasi halis ah: syncope, burburkii, cadaadis intracranial sare, hyperthermia, qalal, xanuunada function muuqaal ah, dhidid soo kordha, methemoglobinemia, bradycardia, curyaannimo, iyo kooma. Taasi waa sababta ay muhiim ah in aan si is-wadnaha, iyo daroogada qaado si adag sida ay shuruudaha ku takhasusay!

Haddii calaamadaha lagu qeexay waxay u baahan tahay ka saarida therapy daroogada iyo qabashada loogu talagalay xasilinta xaaladda bukaanka ah.

analogs

Medicament "Kardiket» (CHWARZ Pharma, Germany) - mid ka mid ah dawooyinka ugu badan generic (analogs) daroogada "Izoket" (buufis). Qiimaha bedel this waxa ay ku xidhan-fiirsashada oo ah walaxda firfircoon iyo tirada kiniinka ah ee xirmo.

Tusaale ahaan, wakiilka in loox oo 20 mg "faafiyo Kardiket" (20 kumbiyuutarada. On baakadka) waa ka 62 ilaa 72 rubles, halka diyaarinta la mid ah, kaliya ee qiyaasta ah 40 mg iyo tiro ka mid ah 50 gogo ', ayaa qiimaha a of 210-220 rubles.

Koox ka mid ah daawooyinka "Nitrosorbid" macmalay shirkado dhowr Ruush, iyo noocyo kala duwan oo loo sii daayo, sidoo kale, waa daroogada bedel "Izoket". Analogues kooxdan leeyihiin magaca "Nitrosorbide-Rusfar", "Nitrosorbide", "Nitrosorbide NS", "Nitrosorbide-UWI."

qiimaha

In farmasiyada Ruush yeelan doonaan in ay bixiyaan ka 365 si ay u 470 rubles halkii samaynta qiyaasta "Izoket" (buufis). Qiimaha waxaa la aasaasay ku xiran tahay meesha uu outlet tafaariiqda iyo status. On websites iibiya dawo laga iibsan karaa qiime ka hooseeya farmashiyaha caadiga u dhow gurigaaga. Laakiin marka amro Internetka yeelan doonaan in ay bixiyaan 200 rubles loo gaarsiiyo ama helaan beeca xorta ah ee hore Baaragaraafka, taas oo aan la had iyo jeer ku haboon ku yaal juquraafi.

Sidoo kale, farmashiyaha kasta oo aad ka iibsan kartaa baakadka (10 fijaan) xal urursan, waayo, faleebo "Izoket". Its qiimaha kala duwan 906-980 rubles.

Guudmarka

Daawada waxaa soo saaray shirkadda Jarmal "YUSB Pharma GmbH". nolosha shelf ee shan sano. Terms of sale - joogitaanka dhaqtar kuu qorin. Ka dib markii muddo dheer la isticmaalo waxaa lagu talinayaa si loo hubiyo waxqabadka sprayer ah. qoraalka ee buufis baa la soo siibay ka fallaadha hoose. Marka dareere ah uu gaaro heerka ay tahay in ay u noqon si aad u hesho daroogada cusub, tan iyo isticmaalka dhalada ah ee hadda jira ayaa suuragal ah keliya in yar janjeerin, taas oo tube caanonuug ah la Hawiyaha ah ee dareeraha la.