"Levothyroxine": diiwaanka, dib u eegista, sharaxaada, analogs

Waa maxay 'qorayaasha Levothyroxine "? Tilmaamaha loogu isticmaalo, dhakhaatiirta dhab ah oo ku saabsan qalab this lagu hoos lagu soo bandhigay doonaa. Waxa kale oo aanu kuu sheegi ah oo ku saabsan foomkan, taas oo sii daayo daawada this, haddii uu qabo wax sababo iyo waxyeelo, intii lagu beddeli karaa, iyo wixii la mid ah. d.

Halabuurka The oo daroogada ah iyo foomka fasaxa ay

waxaad ka iibsan kartaa "Levothyroxine" daroogada In wixii foomka? Tilmaamaha loogu isticmaalo, dib u eegista dhakhaatiirta ayaa sheegaya in dawadan waxa laga helayaa in kiniiniyada. In sale ay yimaadaan in qadarka soo socda: 50, 25, 100,75, 150, 125, 200 ama 175 mcg. Ay qayb firfircoon waa sodium Levothyroxine.

qalab kala soocista pharmacological

Waa maxay qalab caafimaad "Levothyroxine"? Tilmaamaha loogu isticmaalo, taas dib u eegista qalab ku jira macluumaad ku saabsan xaqiiqada ah in ay tahay hormoonka thyroid ka, taas oo uu leeyahay asalka ah synthetic.

In yar ka qaataan daawada waa inay awoodaan inay tijaabiso saamayn dhiska (in uu yahay, in ay kicin wax soo saarka protein). Muga celceliska medicament kordhiyaa dhaqdhaqaaqa ee baahida dhexe dareemayaasha iyo wadnaha iyo nidaamka unugyada oxygen, shiid borotiinka firfircoonaan iyo sidoo kale baruurta iyo carbohydrates.

Iyadoo la tixgelinayo qaadasho sare ee daroogada ka caawisaa si loo yareeyo wax soo saarka ee hormoonnada ah pituitary iyo hypothalamus in waxa soo saarey qanjidhada hormoonada jidhka (maskaxda).

The pharmacokinetics ee alaabta, daawooyinka

Halkee iyo sidee dheer dawada la nuugo "Levothyroxine"? macnaheedu waa barashada ayaa sheegay in ka dib markii nuugista afka daroogada waxaa laga xiidmaha iyo waa qiyaastii 49-78%.

Qaadashada soon daawo si weyn u kordhiyaa nuugista of qayb firfircoon. fiirsashada wax soo saarka ugu badan soo gaadhay ka dib qiyaastii 5-6 saacadood.

protein plasma Communication ka badan tahay 98%.

Qaybinta daroogada qaadataa meel inta badan ee beerka iyo in murqaha, iyo maskaxda.

The bar-nolosha 1 toddobaad ah. Qiyaastii 15% ka mid ah daroogada saxarrada la bile ah oo dhex kelyaha - foomka of conjugates qaab unmodified, siday u kala horreeyaan.

Tilmaamayaasha for isticmaalka dawadan

Maxaa la qoondeeyey karaa dawo "Levothyroxine"? Tilmaamaha ku lifaaqan habkan ay muujinaysaa calaamado muujinaya soo socda:

• goiter isku dhafan;
• sare iyo hypothyroidism aasaasiga ah,
• Iskujira Therapy of goiter sun ah, Graves, shalalka , iyo thyroid kelyaha qanjirka euthyroid;
• cretinism;
• ka hortagga ku xoogeystay ka dib markii qaliin on thyroid ka (ka dib saarista burooyinka halista ah iyo patrilineal).

Sidoo kale sodium Levothyroxine loo isticmaalo kala duwan ogaanshaha xakamaynta thyroid imtixaanka.

Sababo in la helo

Waxaad ma qaadan karaan daawada "Levothyroxine" hoos leexashooyinkaasi kasta? Kiniiniga waxaa loo arkaa noo by, waxaa reebban in ay isticmaalaan la tayroodh, Wadnaxanuun myocardial (acute). Waxaa sidoo kale ahaan uu la diidmo in wax salka (i.e., sodium Levothyroxine) aan la daaweyn la'aan binyrebarkhormon.

Drug "Levothyroxine": tilmaamaha loo isticmaalo

Reviews ku saabsan daroogada this ku jira macluumaad in ay saameyn la arko oo kaliya ka dib markii 7-13 saacadood ka dib bilow ah therapy. Laakiin tani kaliya kiiska waa haddii daawada ayaa loo magacaabay by maragga iyo qiyaasta saxda ah.

mugga of daroogada tixgeliyo daaweynta leexasho la aasaasay oo ku saleysan shaqsi ku xidhan cadeymaha la heli karo. Sida caadiga ah bilowga ah ee therapy medicament firfircoon waxaa loo isticmaalaa in qiyaasta ah 12.5-25 mg maalintii hal mar (25-30 daqiiqo cuntada ka hor). Si kastaba ha ahaatee, sida daaweynta dayactirka ah, lacagtaas ay gaari karaan iyo 200 mcg maalin kasta.

Waqtiga baaritaanka daroogada kala duwan ay maamusho waallayn in cadadka 3 mg ama 14 maalmood at 200 ug mar maalin kasta.

Waayo, daaweynta dabiiciga ah lagu dhasho ee hypothyroidism ilmaha ee ka yar 6 bilood, siin 25-50 lacag mg ilaa 1 sano - 60 mg, iyo da'da 1 ilaa 5 sano - 100 mcg. Carruurta waaweyn (6 ilaa 12 sano) ee Levothyroxine sodium waxaa maamula ee dose oo ah 150 micrograms. Caruurta qaangaarka ka dib markii 12 sano ay yihiin 200 micrograms maalin kasta.

Dadka waaweyn ee qaba cudurka this, sida tayroodh, talinaynaa qaadashada 25-100 mg ah ee daawada maalin kasta. Marka qiyaasta this waxaa si tartiib ah kor u kacay (laba ama saddex toddobaad kasta, 25-50 g). Sidaas darteed, mugga oo ka mid ah qeybaha medicament iyo taageero ku saabsan yahay 125-250 micrograms maalin kasta.

Ka dib saarista qalliinka qabsashadii ah daroogada buro malignant qadarkuu of 300 g.

Marka goiter euthyroid, iyo sidoo kale si looga hortago in ay dib-u-formation of daawada loo soo qoray in dadka waaweyn ee lacagta ah ee 75-200 mg, iyo carruurta - 12.5-150 micrograms maalin kasta.

Dhibaatooyinka ay keento ka dib markii la helo medicament

Ma qaadan karaa "Levothyroxine" daroogada iyo khamriga? Si aad u taariikhda, xidhiidhka ka mid ah qalab ka la khamriga aan la aasaasay. Si kastaba ha ahaatee, inta lagu guda jiro daawaynta daawooyinka hormoonnada ah laguma talinayo xadgudub cabitaanka khamriga.

Sida saamayn kaddib qaata daawada hoos u eegid, bukaanada la kulmi karaan astaamaha tayroodh. ka mid ah dalalka soo socda: wadno, tachycardia, arrhythmia, madax-xanuun, angina, gariirka, isku yaacsanaan, dareen of nasasho hoose, rabshooyin hurdo, casiraad, miisaanka oo yaraada, tabar-dari muruq, shuban, matag, xanuunada caadada.

qalabka caafimaadka badinta

Xaaladdan oo ah qiyaasta xad dhaafka la daroogada this bukaanku leeyahay calaamado in ay yihiin caan ku tayroodh daran ama dhexdhexaad ah. therapy The astaamaha waxaa loo isticmaalaa sida daawada loogu talagalay xaaladaha sida. Xaaladdan oo kale, daawada isla markiiba wuu rogay.

Waxa kale oo suuragal ah inuu ku meeleeyo beta-blockers. Marka la isticmaalayo qaadasho xad dhaaf ah plasmapheresis waxaa la sameeyaa. Waxaan ma dhihi karo in haddii ay taasi ku, kelyaha xumaada.

Dhexgalka daroogooyinka kale

Ma qaadan karaa "Levothyroxine" daroogada iyo calcium? element Tani, sidoo kale hydroxide aluminium iyo sucralfate yareeyo absorbability ah oo ah walaxda firfircoon ee medicament ugu horeysay ka mareenka caloosha iyo mindhicirka.

Sidoo kale waa in la ogaadaa in element ugu muhiimsan ee daroogada potentiates tallaabo ee xinjirowga lidka ku ah iyo yaraynaysaa oolnimada wakiilada hypoglycemic (afka).

In bukaanka qaba diabetes mellitus iyo hypothyroidism in daaweyn bedelay hore ee daawada hormoonka thyroid u badan tahay in ay kordhiyaan baahida loo qabo wakiilada hypoglycemic (afka) ama insulin.

Bishydroxycoumarin, salicylates, clofibrate iyo furosemide si sahal ah Leexin kartaa sodium Levothyroxine ay Xiriir la leh borotiinada plasma.

Cholestyramine yaraynaysaa nuugista of walxaha firfircoon ka mareenka caloosha iyo mindhicirka.

Markii la isticmaalayo "ritonavir" leeyihiin itimaalka sare oo kor u qaaday dalabka "Levothyroxine".

Inta lagu jiro codsiga ah "sertraline" in dadka qaba hypothyroidism hoos saamaynta sodium Levothyroxine.

Iyadoo gelitaanka "Chloroquine" ayay u badan tahay in ay kor u dheefshiidka ee Levothyroxine iyo TSH uruureen.

Naas-nuujinta iyo uurka

Inta lagu jiro nuujinta iyo uurka tixgeliyo daroogada waa in la isticmaalaa oo kaliya ka yar kormeer dhakhtar. Isticmaal lala wakiilada tireostaticheskimi xilliga uurka waa u. Tani waxay la xidhiidhaa halis kordhaysa oo ah hypothyroidism in ilmaha caloosha ku jira uurka ka.

tilmaamaha gaarka ah ee qaata daawada

Maxaad daroogada "Levothyroxine" iyo timaha oo la xiriira midba midka kale? Xaqiiqada ah in xadgudub ka dhan ah qanjirka thyroid in bukaanka laga yaabaa in ilaa xad uu timaha laga badiyay. Si kastaba ha ahaatee, marka ay tani tilmaan dheelitir la'aanta medicament hormoon ku dhowaad gebi ahaanba ka reebtay.

gaariga ku xiran si taxadar leh u daran qoray in dadka qaba cudurrada wadnaha, ay ka mid yihiin dhiigkarka, cudurka halbowlaha wadnaha iyo wadnaha oo shaqadiisa gaba. Xaaladahan, qiyaasta daawada waa in la dayactiray qiyaasta hoose, waxaa sii kordhaya si tartiib ah oo la farqiga weyn.

bukaanada waayeelka la duration sii dheeraaday ee cudurada sida hypothyroidism, therapy, waa in ay bilaabaan si tartiib tartiib ah.

Waayo, daaweynta bedelay qanjirka thyroid dadka ku filnayn shaqada kiliyaha adrenal aan la daaweyn ku filan (dayactirka) la corticosteroids waxaa suuro gal ah dhibaatooyinka adrenal (acute).

daroogada Tan waxaa loo qoray si taxadir leh in bukaanka qaba diabetes mellitus.

Xaaladaha qaarkood, hormoonnada thyroid keeni ama sii myasthenic syndrome (hore).

Daroogooyinka "Levothyroxine" iyo "Eutiroks": ka duwan, dib u eegista

In kasta oo xaqiiqda ah in labada waxaa ka mid ah waxyaabaha la mid ah samaynta muujiyay firfircoon, mid kasta oo iyaga ka mid ah waxay leedahay astaamo u gaar ah. Tan waxa u sabab ugu horrayn si ay xaqiiqada ah in qaybaha dheeraad ah ka mid ah daawooyinka ay yihiin kuwo ku kala duwan.

Sidoo kale, waxaa jira qaar ka mid ah kala duwanaanshaha in tallaabo daroogada. Sida laga soo xigtay jawaabaha dadka bukaanka ah, saamayn daaweynta "Levothyroxine" daroogada arkay 7-13 maalmood ka dib, iyo iyadoo adeegsanayo "Eutiroks" - laba todobaad ka dib.

Marka si sax ah loo isticmaalo, dawada la soo dhaafay waxyeelo ma laha. Sida hore, marmar dhif ah, weli waxay keenaysaa in cawaaqib aan loo baahnayn. Waxaa intaa dheer, waxa dhici kara waxyeello xitaa isbedel yar ee qiyaasta.

In caruurta la suuxdin, ama codsiga qalal "Levothyroxine" daroogada sababa sii daraysa. Sida Eutiroks daawooyinka ' ", ka dib markii ay la isticmaalo ay ka sii daraan sida aan arkay.

Analogs qalab caafimaad

Maxaa bedeli karaa daawada "Levothyroxine"? Analogs daroogada this waxaa laga helaa farmashiyaha oo dhan. Ka mid ah daawooyin sida lagu xusay kara kuwa soo socda: «L-tyroksiini-Pharmak», «L-tyroksiini", "Bagotiroks", "A-Tirok" "Levothyroxine Sodium», «hexane L-tyroksiini", "Eutiroks», «L- tyroksiini akar "," dedaalayo-4 "iyo wixii la mid ah.

Kurtumm

Sida laga soo xigtay war celin ka mid ah kuwii la magacaabay daroogada waxaa loo arkaa arrin wax ku ool ah ay ula qabsadaan hawsha. In kasta oo mararka qaarkood, daawooyinka waxay keeni kartaa waxyeelo qaar ka mid ah.

Sida laga soo xigtay khubaro, si madax bannaan u isticmaalaan ah wakiilka "Levothyroxine" hormoon gebi ahaanba la mamnuucay. Its dhakhtar oo kaliya ee amarada la qaadi karo, taas oo ku xidhan caafimaadka ee bukaan-socodka iyo qaab shakhsi ah. Tan waxa u sabab xaqiiqada ah in daawooyinka hormone yeelan karaan saamayn aad u awood badan jirka insaanka iyo hormoonnada guud ahaan.

Sidoo kale waa in la ogaadaa in daawo kale ah laguma talinayo. Ka dib oo dhan, waxaa si fudud u keeni kartaa dhalanrog ka mid ah natiijooyinka daaweynta.