"Lidocaine" (cadar): tilmaamaha loo isticmaalo, dhabta ah

Si aad u baabi'iyo xanuunka, u isticmaalaan noocyo kala duwan oo suuxinta. Haddii xanuunka waa in si toos ah loo saaro qayb jidhka, codsan diyaar u socoto la mariyo. Asal ahaan waxa Delfin, cadar, jel. "Lidocaine" ayaa foomamka sii daayo kala duwan. Waayo, ka saarida xanuun leh meesha ay dhibaatadu saameysey waxaa inta badan waxaa loo isticmaalaa in cadar ah 5%.

The Halabuurka iyo qaab "Lidocaine"

"Lidocaine" (cadar) waxaa si gaar ah loogu talagalay isticmaalka dibadda. diyaarinta waxaa ka mid ah walxaha firfircoon sida hydrochloride lidocaine iyo dihydrochloride klorhexidinsprit. daawo More ka kooban yahay qaybaha dheeraad ah sida gietelloza (hydroxyethylcellulose) iyo glycerol.

Daawada waa gel ah oo hufan.

Taa baddalkeeda, hab waxaa ka buuxa galay tuubooyinka aluminium 15 iyo 30 g iyo 25 g of dhalooyinka mugdiga ah. kartoon waxaa gundhig ay la socdaan cadar "Lidocaine" edbinta.

daroogada Tan waxaa lagu sii daayay ma aha oo kaliya ee foomka of cadar, laakiin weli qaab buufis, iyo in ampoules loogu talagalay duro.

Daawada waa in lagu kaydiyaa meel qabow oo qalalan iyo la heli karo ee carruurta. nolosha shelf waa saddex sano oo cadar ah, in uu ka dib daroogada aan la isticmaali Karin.

tallaabada pharmacological daroogada

daroogada iska leh fasalka IB-antiarrhythmic. Waxay u dhaqmo sida suuxinta degaanka iyo waa derivative ah acetanilide. Lagu gartaa xuub hawlaha xasilinta.

Oo macnaheedu yahay "Lidocaine" (cadar) yaraynaysaa muddada saameynta ku iman karta iyo muddo wax ku ool ah in fiiloyin Purkinje, cadaadinayaan hawlo iyaga u gaar ah. blocks daroogada hawlaha koronto depolarized, goobaha arrhythmogenic, laakiin in yar saamayn ku shaqada koronto ee unugyada caadiga ah.

Marka loo isticmaalo qaabab srednelechebnyh of daawo lahayn saamayn weyn ku contractility myocardial iyo caanuhu AV-tabinta. Haddii "lidocaine" waxaa loo isticmaalaa sida daroogada ah antiarrhythmic iyo talooyin / v, bilawga ah ee ay tallaabo dhacdaa 45-90 ilbiriqsi ka dib, iyo saamaynta qiyaastii 10-20 daqiiqo. Marka saamayn / m medicament la dareemi karaa 5-15 daqiiqo ka dib iyo muddada ay tahay 60-90 daqiiqo.

Daawada waxaa loogu talagalay terminal, dhexgalka iyo suuxinta tabinta.

Daawada la dhayayo saleyn karaa meesha dhibaatada dhawr jeer maalintii. Tirada talinayo codsiyada - 3-4 jeer maalintii.

Marar badan la isticmaalayo 2% "Lidocaine" gel galinta galay hunguriga ama qalab caafimaad dhuun. Daawada dahaarka Bir gaarka ah ee caafimaadka. Haddii suuxin lahayn saamayn ama saamaynta daroogada waxay ahayd dayac badan, codsiga lacagta lagu celceliyo.

In cadar isla-fiirsashada waxa lagu isticmaalaa cilmibaadhis berrinkii urology loogu tala galay dumarka, halkaas oo ay lubricates xuub-axaleedka of kaadi mareenka. On isticmaalka daroogada ay dhacdo in this waxaa saameeya dhismaha shakhsiga ah ee kaadi mareenka. gel More loo isticmaalo galinta ee tuubada galay kaadi ragga, sidaas baabbi'in ilaa 100 mg ah ee daawada.

Si aad u xanuun ee barar ah bukaanada kaadi yareeyo waxaa maamula hal qiyaas ah oo cadar oo ay la socdaan daawooyin kale uusan waallayn. therapy Tani socdaa illaa shan maalmood.

Gel la lidocaine loo isticmaalo inta lagu guda jiro waxbarasho ee endoscope kaadi. Sidaas darteed, si ay u buuxiyaan oo u ballaadhiyo kaadi in la isticmaalo 30 ml of diyaarinta this. dose Tani waxaa maamula laba qaybood oo la bareeg gaaban. kaadi waa waqti yar halka demisay.

Waxaa sidoo kale loo isticmaalaa in la isku qurxiyo, "lidocaine" (cadar) - waayo Jeexitaanka ka saarida timaha iyo meelaha kale ee xasaasiga ah ee jirka.

Ka dib markii duridda waxaa la nuugo ku dhowaad gebi ahaanba. Si degdeg ah u qaybiyeen. At ay la dhexgalo borotiinada saamayn ku fiirsashada of qayb firfircoon ee dhiigga, taas oo ah 60-80%. Drug metabolized inta badan ee beerka, iyadoo dhirfinaya muuqaalka kore ee metabolites firfircoon oo saamayn saamaynta ku daweynta iyo sun ah, gaar ahaan ka dib markii faleebo (in ka badan maalmood ama ka badan).

The bar-nolosha ee daroogada waxay u egtahay in ay biphasic leh wajiga qaybinta 7-9 min. Waxay ku xiran tahay qiyaasta iyo maamulka waxaa loogu talagalay 1-2 saacadood, si tartiib ah kor u kacay in saddex saacadood ama in ka badan in muddo ah / faleebo (in ka badan 24 saacadood). Saxarrada kelyaha ee foomka of metabolites, 10% ka soo badelin.

Waxay cadarkan "Lidocaine": codsiga

Waxay cadarkan "Lidocaine" (5%) ayaa codsiga la mariyo oo keliya. Waxay yaraynaysaa xanuunka ee meelaha dhaawac maqaarka (nabro, iyo burbur,) iyo xuubka afka. Waxa loo isticmaalaa in gobolka perianal.

Sababo isticmaalka

Isticmaalka gel "Lidocaine" (tilmaamaha ka hor inta la isticmaalayo waa in la akhriyo) ficil ahaan ma keento dhibaato, laakiin, inkastoo taasi, qalab aan la isticmaali karaa haddii ay waxyeello xabka. Xaaladdan oo kale, kor u nuugista ee suuxinta, taas oo keeni karta in dhacdo ee sumoobo systemic.

Ha isticmaalin daawada ee carruurta (ilaa laba sano) iyo in ay dhacdo diidmo in lidocaine.

"Lidocaine" (cadar): tilmaamaha loo isticmaalo

xaddiga daroogada loo isticmaalo daweynta maqaarka, waxay ku xiran tahay xaaladda bukaanka iyo aagga in la daweeyo, vascularity unugyada. On isticmaalka ah oo cadar ku saameeyaa qaybaha dulqaad shaqsi. Ka dib oo dhan, waxaad isticmaali kartaa daroogada ee qiyaasta ugu hooseeya ama waqti cayiman inay ka tanaasulaan oo ay codsiga.

"Lidocaine" -maz (hubiyo Buugga mararka qaarkood wax aan macquul aheyn si aad u dalbato daroogada) waxaa maamula iyadoo ay wada joogaan tilmaamo gaar ah ee dadka waaweyn iyo carruurta ka da'da laba iyo toban.

Waayo, cadarkan xanuun istareexsan waa in la dalbadaa at dose oo ah 1-2 garaam oo dhawr jeer maalintii. Loogama - 3-4 codsiga.

Carruurta ka yar laba iyo toban sano jir waa in ay isticmaalaan gel ah si taxadir leh. Halkan waxaa lagama maarmaan ah inaan ka dhaansado si ay xaqiiqada ah in reer bioavailability da'da this 100% dareenka. Sidaa darteed, qiyaasta ugu badan ee la ogolyahay waa in aan ka badnayn 0.1 g / kg miisaanka jidhka ilmaha in uu yahay 5 lidocaine mg halkii miisaanka jidhka kiilo. bareeg u dhaxeeya dalabka ah oo cadar waa in aanay noqon wax ka yar siddeed saacadood.

Daawada codsatay in xabka inta lagu guda jiro nidaamka sida ogaanshaha dhuunta, dhuun iyo hunguriga. Sidoo kale inta badan lahu qalab cadar for sahanka. qalabka Processing "lidocaine" waa la fuliyay iyo inta lagu guda jiro dhacdo. Wakhtigan bixisay 0.2-2 cadar g. Haddii suuxin this waxaa la siiyaa natiijada, ka dibna 2-3 daqiiqo ka dib hawl la mar kale soo noqnoqda.

Qiyaasta ugu badan ee maalin walba qof weyn waa 300 mg (6 g of gel). Ladies daweeyey waaxda urology kaadimareenka xabka 3-5 ml of diyaarinta. Waayo, dadku waxay la isticmaalayo cadar isla markiiba ka hor sanka qadarkuu of 5-10 ml. Qiyaasta ugu badan ee maalin kasta ee carruurta waa 4.5 mg / kg.

In ilkaha, Cadarkii waxaa laga codsadaa in xuubka afka suuxinta xiga. bareeg u dhexeeya codsiyada ah oo cadar waa 2-3 daqiiqo. gel More waxaa loo isticmaalaa in ka kaxayntu ay of dhagax ilkeed. Wixii diyaarinta this waxaa ay suuxaan gelin gingiva iyo qoorta ilig 2-3 daqiiqadood ah. Codsiga of cadar soo codsatay in xabka ee saabka afka aphthas ku formation iyo erosions.

Inta badan isticmaasho "Lidocaine" (cadar) ee ka saarida timaha. Gaar ahaan ku habboon diyaarinta goobta Jeexitaanka ka saarida timaha. Sida a daawada suuxinta daawo loo isticmaalo 3-3.5 saacadood ka hor nidaamka ka saarida timaha. First gel ah waxaa laga codsadaa in ay dusha maqaarka, oo intaas ka dib ku duudduubtay oo leh meesha la doonayo ee lagu duubo cuntada.

waxyeellooyin

"Lidocaine" (cadar), mararka qaarkood, waxay keeni kartaa cuncun maqaarka, sida daroogada, marka lagu daro lidocaine, waxaa ku jira wax dheeraad ah oo tones propylene. Sidoo kale waa dhacdo suurto galka ah ee waxyeelo sida urtikaria, barar. Xaaladaha halkii dhif shoog.

Haddii ay dhacdo in sumoobo systemic ay sabab u tahay codsiga ah ee daawooyinka xanuunka dibadda waxyeelo waxaa lagu arkay hababka dareemayaasha iyo wadnaha dhexe.

Habdhiska symptomatology muujiyey sida walaac, isku yaacsanaan, walaac, caro, iyo jaahwareer. Mararka qaar waxaa jira jahwareer, tinnitus, arag cawaran, jiirraago, yaqyaqsi iyo hungaaeada, gariir, gariirka. Waxaa jiray calaamado muujinaya calaamado cuncun, luminta dareenka luqadda iyo meelaha ku wareegsan afka.

On qayb ka mid ah nidaamka wadnaha ee bukaanka, xaaladaha qaarkood, hawlaha murugada myocardial waxaa laga soo minguuriyay, iyo sidoo kale vasodilatation durugsan, kaas oo ka dhacay ka dib markii hypertension iyo bradycardia. hannaankii A la mid ah waxay keeni kartaa arrhythmia iyo, sida natiijo ah - wadnaha oo shaqadiisa gaba. Aad ayay u yar methemoglobinemia.

Dhexgalka daroogooyinka kale

"Lidocaine" (cadar) isku dhafan oo daawooyinka anti-arrhythmic uu sababi karaa curyaannimo ama complete wadnaha. gobolka noocan oo kale ah ayaa lagu arkay bukaanka lidocaine isticmaalo amiodarone, tocainide ama procaine.

daroogada Antiepileptic isku dhafan oo lidocaine yarayn kartaa fiirsashada daroogada ee hab dhiigga. "Phenytoin" maamula intravenously, waxay kordhin kartaa guryaha cardiodepressivny of qayb firfircoon.

Isku darka leh beta-blockers kordhin fiirsashada of lidocaine ee dhiigga. Saameyn la mid yahay "nadolol."

H2-ku Doodeen, sida "cimetidine", sii kordhaya shiid cagaarshowga of qayb firfircoon, taas oo kordhinaysa xaddiga sumoobo lidocaine.

Hypokalemia, taasoo waxaa dhaliyey isticmaalka "acetazolamide" durayo, ka hortagtaa tallaabada of lidocaine.

Waxay keentaa waxyeelo isticmaalo isku mar ah daroogada la vasoconstrictors.

tilmaamaha gaarka ah

Ha soo rogi "Lidocaine" (5% cadar) on xabka ee saabka afka, ama haddii ay jiraan waa astaantii bukaanka ogaado sepsis.

Si looga fogaado nuugista systemic, waxaa lagama maarmaan ah in la isticmaalo daawo taxaddar anemia, methemoglobinemia, iyo sidoo kale la'aan dehydrogenase glucose-6-phosphate.

Marka cadar xasaasiyad waa in isla markiiba la joojiyo isticmaalkeeda iyo is ogow of waxyeelo ah.

"Lidocaine" aan qoray in bukaanka ka cabanaya hypovolemia, iyo sidoo kale isagoo xannibaad muruqyada wadnaha iyo khalkhal kale ee tabinta wadnaha.

Taxadarka daroogada loo isticmaalo, haddii ay jirto hawl gabsiiya wadnaha, bradycardia arkay ama murugada neefsashada.

Subject tilmaamaha halista waxyeellooyinka ka yimaada habdhiska dhimirka waa ay yar tahay. Haddii uu jiro dareen gaar ah ay u daroogada ee bukaanka "Lidocaine" daawo loo isticmaalo si taxadir leh u daran. In fal-celinta xasaasiyadda ku taagayo of para-aminobenzoic cross acid in lidocaine nuglaato lama ogaan karo.

Daawada waa in la isticmaalaa si taxadir leh inta aad uurka leedahay, sida waxbarashada oo muujinaya saameynta oo ah walaxda firfircoon waayo, midhaha soo socda, oo aan lagu sameeyey. Khubarada ku talinaynaa in bilaha ugu horreeya ee uurka sida ugu macquulsan in ay ka fogaadaan isticmaalka daroogada.

"Lidocaine" galaa caanaha naaska ee qiyaasood aad u yar oo aan saamayn xun ku horumarka ilmaha.

kelyaha ma keeno isbedel la taaban karo ee pharmacokinetics marka la isticmaalayo "Lidocaine" (5% cadar).

In joogitaanka beerka waa mid gabi ahaanba ka tanaasulaan codsiga ah ee daroogada, ama in la yareeyo si ay ugu yaraan isticmaalka qaadasho. Marka laga codsadaa in ay wejiga ka dhigan tahay waa in aad hubisaa in daawada aan ku dhuftay in isha ka dhigi.

badinta daroogada yaabaa inay ku dhacaan sabab u sumoobo systemic iyo codsiga ah ee suuxinta ee degaanka waxaa keena uruureen sare oo ah walaxda firfircoon ee dhiigga. Waxaa dhirfinaya muuqaalka waxyeellooyinka la xidhiidha tallaabo oo ka mid ah hababka dareemayaasha iyo wadnaha dhexe.

Xaaladdan oo kale, u fuliyaan daaweynta ku haboon. Bixi marin-haweedka, isku day inaad si loo baabi'iyo dioxide kaarboon ka. jirka bukaanka ah, waxaa soo bandhigay oxygen ama Neefta macmal ah.

Haddii gariir halkaas, ka dibna ay la saaro by bandhigid galay shaqeeyo ee succinylcholine qadarkuu of 50-100 mg, iyo / ama diazepam at dose oo ah 5-15 mg. Xaaladaha qaarkood, isticmaalka barbiturates-simaha-gaaban. Dialysis in xaaladda noocan oo kale ah ma siin saamaynta ay ku doonay oo sidaas daraaddeed ma khuseeyo.

Analogs "Lidocaine"

Haddii sabab uun, "lidocaine" (cadar) ee ka saarida timaha ama ma gaarin ujeeddo kasta oo kale, ha ka quusanina, waxa ku filan in ay bixiyaan si ay u bedelay taas macnaheedu waa daroogada, ka mid ah, kuwaas oo dareenka:

• "Naropin";
• "Bulivakain";
• "Ultrakain DS";
• "Novocaine";
• Cream "EMLA";
• "Mydocalm";
• "Zaldiar";
• "Artifrin";
• "Nalbuphine";
• "Diprofool".

Isticmaalka daroogada kasta waxay leedahay astaamo u gaar ah, sidaa darteed waa in la sameeyaa bedelka dhakhtar. Kaliya kiiskan, waxaad ku tashan karaan xulashada awoodda daawada.

Rogaal haween ah oo ku saabsan isticmaalka cadar for depilation

comments badan ayaa helay daroogada "Lidocaine" (cadar). ka saarida timaha isticmaalaya wakiilka this joogsadeen in ay daran. Waxaa si fiican waa ka saaraysaa xanuunka, oo Fayda Xumaanta dareen, kuu oggolaadaan in aad si ay u sameeyaan nidaamka ka saarida timaha waa arrin ammaan ah oo nafisaad intii suurto gal ah. Haweenka cream waxaa laga codsadaa in meesha oo dhan kaas oo lagu dhaqmi doona iyo kaalinta on polyetylen sare iyo hay 2-3 saacadood. manipulations ka dib sida caadiga ah waa xanuun ka saarida timaha waxaa mar dambe dareemay in xitaa meelaha ay u badan oo xasaasi ah oo jidhka ah.

Laakiin qof kasta oo aan ku faraxsan yahay tallaabada of "Lidocaine" daroogada (cadar). Faallooyin aan fiicanayn yidhaahdaan waa aalad gebi ahaanba aan waxtar lahayn, oo waxaa ku dhowaad ma ka saari xanuunka. Mudanayaal Qaar ka mid ah tusaaJe baabi'iyo xanuunka, laakiin in yar oo dareen ah ayaa weli lagu arkay inta lagu guda jiro nidaamka ka saarida timaha. Dad badan ayaa door bidaan in ay isticmaalaan "Lidocaine 'buufiyo oo ay sheegayaan in uu ku simaha in dhowr jeer ka waxtar badan marisay. Tan waxa u sabab ah sifooyinka gaarka ah ee u shaqeeyo.