"Naloxone": tilmaamaha loo isticmaalo, dhigooda dhabta ah

In dhaqanka caafimaad, waxaa jira xaalado ay isticmaalka daroogada natiijada in reaction overdosing ama taban ka xubnaha kala duwan iyo hababka. Inta badan dhibaatooyinka sida la xiriira daroogo opioid'ka. Si aad u dardar bixitaanka jidhka ka, dhakhaatiirta isticmaalo daawada gaar ah. "Naloxone" Drug - aalad si loo wanaajiyo xaaladda la badinta ah analgesics opioid'ka. Waa maxay iyo waxa farsamo ee ay tallaabo? Ina keena aynu isku day inaad fahanto arimahan.

Description of daroogada, halabuurka iyo foomka

Daawo "Naloxone" Codsiga User la xidhiidha antagonist receptor opioid'ka. Its walax firfircoon waa hydrochloride naloxone. foomamka qiyaasta in laga heli karo suuqa dawooyinka, ma aha sidaas kala duwan, waa xal la isku duro iyo kiniiniga. dambe waxaa aad u dhif ah loo isticmaalo in bukaan eegida. qaab hoore ah maamulka mudayo sinta ama xidid, by la barbardhigo, waa mid aad loo jecel yahay. Halabuurka ee xalka, marka lagu daro qayb firfircoon, waxaa ka mid ah set oo ah qaybaha caadiga ah kaabayaal ah, chloride sodium, biyo la safeeyey, acids organic iyo cusbada oo dhanba.

daroogada Available "Naloxone" in ampoules muraayad saafi ah 1 kasta ml mugga. fiirsashada ee xarunta firfircoon ee dose hal waa 0.4 mg.

wax soo saarka buuxiyey oo ku yaal dusha xirmo dahaadhey la cap caag ah oo hufan ee bireed aluminium ama waxa aan ku. pack kasta oo heysta 5 fijaan.

1 ama 2 wareeggeedii baakadaha waxaa la geeyaa kartoon ah, si wadajir ah ula fariimaha loo isticmaalo ee lagu dalooliyo daroogada iyo ampulnam ah. Haddii fijaan oo waxaa lagu qalabeeyay kaatunka gaar ah ama dhibic of jab, mindiyo ay furitaanka sanduuqa ha saarin.

hab ay of action ah "Naloxone" daroogada

Sida kor ku xusan, daroogada "Naloxone" Codsiga User ee la xidhiidha ku Doodeen ee receptors opioid'ka. Taas macnaheedu waa in wakiilka awood u xanibeen receptors kuwan, oon baabi'inta falalka dhexe iyo durugsan xeryahooda ka kooxda opioids. Intaa waxaa dheer, daroogada marka ay maamusho waxay keeni kartaa astaamaha u-barashada ee bukaanka qaba qabatinka daroogada.

Marka la isticmaalayo "Naloxone" xal, kaas oo qaab hawleed kor lagu sharaxay, saamaynta ku dhacdaa waqti gaaban. Marka intravenously maamula daroogada dhaqan ee 1-2 daqiiqo, muruqyada dhexdooda 5 daqiiqo ka dib. Muddada saamaynta ku daweynta halka sidoo kale ay ku xiran tahay wadada of xal maamulka. Haddii xalka la soo bandhigay galay muruqa, daroogada ka shaqeeya 45 daqiiqo, iyo duro xididka - oo aan ka yarayn 4 saacadood.

Khubaro inta badan loo isticmaalaa in lagu daweeyo bukaannada "Naloxone" xal. Kiniiniga, in la barbardhigo, waa mid daciif ah oo muddo kooban ah.

Walaxda firfircoon ee daroogada kala diray in beerka si metabolites. Muddada ay bar-nolosha waa yar yahay, oo kaliya 30-80 daqiiqo. 70% qiyaasta "Naloxone" maamula saxarrada kelyaha 3 maalmood gudahood.

Faa'iidada ugu weyn ee daroogada "Naloxone" waxaa loo arkaa in ay awood of formation ku xiran tahay isaga.

Tilmaamayaasha

Xaaladaha qaarkood, waxaa lagu talinayaa in isticmaalka daroogada "Naloxone"? Tilmaamaha loogu isticmaalo daroogada ku qoran liiska faahfaahsan ee xaaladaha isticmaalkeeda waa heer sare ah suurad wacan. First of dhan, waxaa lagu qoray in bukaanka qalitaanka ka dib. Isticmaalka daroogada "Naloxone" (analogues ayaa sidoo kale inta badan loo isticmaalaa in muddada postoperative) , haddii ay taasi waxay ka caawisaa in ay si deg deg ah ka dawlad daawada hurdada keeno bukaanka. "Naloxone" Daawada loo isticmaalo iyo in la baabi'iyo saamaynta sumowga ethanol, analgesics badinta, barbiturates iyo benzodiazepines.

Inta ay la isticmaalo waa laga caddeeyey in ay dhacdo dhalashada ilmaha in deegaan ay hooyada xilliga foosha ayaa la soo bandhigay analgesics opioid'ka. Sida caadiga ah, carruur, kuwaas oo ay jiraan dhibaatooyin neefsashada lama filaan ah. Drug "Naloxone" iyaga tiraa iyo waxay ka caawisaa dhaqaajiso shaqada neefsashada. Solution oo waxaa inta badan loo isticmaalaa sida qalab lagu ogaanayo in xaaladood oo looga shakisan yahay joogitaanka qabatinka daroogada ee bukaan-socodka ah.

Waa in la ogaadaa in xaalad kaliya ee codsiga of qalab this - tilmaamo adag. Taasi waa sababta dhaqanka caafimaad, waxaa si adag loo isticmaalo on warqad dhakhtar oo hoos kormeer.

sababo

Ka mid ah sababo ah in isticmaalka "Naloxone" tilmaamaha diyaarinta loo isticmaalo waxaa loola jeedaa xaaladaha iyo cudurada soo socda:

• Diidmo in walaxda firfircoon ama mid ka mid ah qaybaha daroogada,
• cudurka wadnaha (organic);
• beerka daran iyo cudur kalyaha ah,
• ku tiirsanaanta jirka on analgesics opoidnyh.

Taxadarka waa in loo qoro si ay haweenka uurka leh ee ku tiirsanaanta daroogada, sida astaamaha u-barashada, taasoo keentay in laga sal-dhigida ee xalka xun u saameyn karto xaalad uurjiifka. Isla sidaas u dhaqmaan isticmaalka in dhallaanka ay hooyadood inta ay uurka leedahay si xun daroogo opoidnymi.

Si kastaba ha ahaatee, faa'iidooyinka daroogada waa in ay ka sii weyn tahay khatarta ka iman karta dhibaatooyin ee bukaanka. Waxaan idin xusuusineynaa in kaliya dhaqanka ee daawada "Naloxone". Qoro qaab ku haboon uu dhakhtarka xaadirka ah, bukaan-socodka uu qabanayaa jirin sababo halis ah in isticmaalka daroogada this.

Hababka Isticmaalka iyo Qiyaasta

Qiyaasta iyo wadada maamulka waxaa go'aamiya takhasus ah oo ku saleysan xaaladda hadda ee bukaanka. Waxaan ku siin mudada caadiga ah "Naloxone" xal.

Overdosing daawooyinka xanuunka ee dadka waaweyn ee u baahan hordhaca ah ee 0.4 ilaa 2 diyaarinta mg (1-4 ampoules) intravenously ama intramuscularly. dose A hal talagalay carruurta waxa lagu saleeyaa miisaanka jidhka, waxa ay ka dhigan tahay in 0.005-0.01 mg / kg.

Waayo, ay ka saareen bukaanka ka hurdo-laaluusheen daroogada (muddada postoperative), daroogada waxaa maamula intravenously in qadarka soo socda: dadka waaweyn ee dose oo ah 0.1 mg raacay by dib-u-hordhaca ah in ay dib u soo kabashada ee neefsashada lama filaan ah, carruurta - 0.01 mg / kg miisaankiisa jirka si loo soo celiyo neefsashada.

xal dhallaanka waxaa intravenously maamula, intramuscularly ama perkusionno qadarkuu of 0.1 mg / kg miisaankiisa jirka mar.

Haddii loo baahdo, daroogada lagu ogaanayo sida uu daroogada la maamulo intravenously at dose oo ah 0.08 mg.

dhibaato

Waxaa ka mid ah cawaaqib xun ee isticmaalka daroogada, guide "Naloxone" sheegaye shuruudaha soo socda:

• lalabo, waxaana suurto gal ah in ay la rabitaanka mantagi;
• cadaadiska dhiigga ee sareeya,
• garaac aan caadi ahayn;
• gariir iyo gariir,
• dhidid.

In bukaanka qaba ku tiirsanaanta opioid'ka, isticmaalka daroogada waxay keeni kartaa shuban, xanuun ah deegaamaynta aan la garanayn, barar xabka sanka, dareen daal aad u daran, qarqaryo, caloosha iyo casiraad xiidmaha. ifafaale Kuwan waxaa loo arkaa caadiga ah ee daroogada "breaking." Waxay kordhin dhowr tobanaan daqiiqo.

analogues Drug "Naloxone"

Ma suurogalbaa in qof bedelo kooban of diyaarinta la mid ah daroogada "Naloxone"? Analogues ee xarunta this taariikhda yar yihiin. Waxaa ka mid ah daroogada "Narcan" "Naltrexone", "Tsiklozotsin" iyo "Narkantin". Waxay guryaha pharmacological, tilmaamo iyo sababo la mid ah kuwa ku jira xal iyo kiniiniyada "Naloxone" waa. Sidaas awgeed, waa loo baahnayn si ay u isticmaalaan in joogitaanka xasaasiyad in bukaanka xarunta a sida hydrochloride naloxone.

Si kastaba ha ahaatee, waxaa leeyihiin faa'iidooyin ay. Tusaale ahaan, "Naltrexone" daroogada ka shaqeeya wakhti dheer ah (oo ku saabsan 24-ka saac) iyo waxaa laga heli karaa inta badan qaab kiniin ama irbada saacadda afka. Waxaa inta badan loo isticmaalaa for sireed ka qabatinka by kaabsoosha tolidda maqaarka ee xalka ka yar.

Reviews of diyaarinta

Ka mid ah dhakhaatiirta "Naloxone" daroogada uu leeyahay sumcad wanaagsan. Sida laga soo xigtay iyaga, waxay ka caawisaa si loo badbaadiyo dad badan oo buka haddii ay dhacdo badinta shil ama ula kac ah ee daroogada ka tirsan ee analgesics iyo / ama opioids. Inkastoo tiro badan oo ah sababo iyo waxyeelo, daroogada waxaa loo arkaa inay xad ammaan in la isticmaalo. Waxaa intaa dheer, iyada oo ay caawimaad, waxaad Muujinaysaan kartaa qabatinka daroogada qarsoon.