"Poliglyukin": tilmaamaha loo isticmaalo, sababo, dib u eegista

"Poliglyukin" - medicament plazmozameshchath antishock fududeeyaa replenishing of qoral. Sidaas darteed, isticmaalka daroogada la reebay Amda ee platelets iyo unugyada dhiigga cas.

Qaab dhismeedka kooban "polyglukin"

Ku saleysan daroogada - dextran. In dhalada galaas ku jira 200 iyo 400 ml oo ah diyaarinta foomka of xal aqueous. Halabuurka daroogada wuxuu ka kooban yahay chloride sodium iyo biyo la isku duro.

pharmacodynamics

"Poliglyukin" edbinta ku saabsan qaab sida isagoo antiagregatnym daawada iyo saamaynta hemodynamic. Daawada waa polysaccharide hydrophilic oo biyo ah qabanaya. Ka dib markii la isticmaalayo daawada qoral la soo celiyay in muddo gaaban markii ay sabab u tahay xaqiiqda ah in uu nuuga biyo ku filan.

qayb firfircoon ayaa miisaan xad sare kelli, si dhiigga oo waa hadiyad muddo dheer, iyo Maamule si tartiib ah u maraa derbiyada markabka. Features of daroogada si uu si deg deg ah loo kordhiyo oo dheer si ay u sii dhiig karka caadiga ah. "Poliglyukin" yaraynaysaa bararka unugyada, celinayo qoral tiraa dabac, taas oo dhacda in weelasha durugsan.

xasiloonida Hakinta waa soo hagaagtay ka dib markii dhiig daaweynta "Poliglyukin" edbinta muujinaysaa in daroogada ka dhigaysa dhiigga yar viscous. In aadanaha, tirooyin caadi, jebiyey ay sabab u tahay horumarka lama filaan ah: microcirculation, socodka dhiigga unugyada ah.

Pharmacokinetics

Digo ee medicament soo saaray jidhka ka inta badan by kelyaha. saarista qayb ahaan waxaa lagu fuliyaa inta lagu jiro maalinta. "Poliglyukin" saaro dhawrsan, qayb aan qiimo lahayn oo dhanba galo unugyada nidaamka reticuloendothelial oo waxaa halkaas ku shubo si tartiib tartiib ah dhacdaa medicament qaybsama. Sababo la xiriira habka this, glucose la soo saaray, taas oo aan la tixgeliyaa sida il tamar. Little "polyglukin" galaa marinka dheef shiidka.

maragga

"Poliglyukin" edbinta ku saabsan codsiga kuu ogolaanayaa inaad inuu ku meeleeyo markii jebiyey socodka dhiigga gaddoonka ah. Daawada ku habboon ee daaweynta ee dalalka of shock iyo Kahortagga (shock septic, sun, gubasho, hawlaha, argagaxa leh). daroogada loo isticmaalo in dhiig la'aan ba'an oo ka dhacay inta lagu guda jiro uurka ah ectopic, dhalmada ama iyada oo sababtu tahay dhaawacyada ay si dhakhso ah loo soo celiyo qoral ah. Solution waa hypovolemia, taas oo ah natiijo ah oo baxsiga plasma (qol syndrome, gubasho). Saamayntii daroogada lagu arkay fulinta tallaabooyinka ka hortagga loogu talagalay ka hortagga lungemboli (lamaguraan, postoperative).

sababo

Ka hor inta daaweynta waxaa lagama maarmaan ah in ay bixiyaan si ay sababo, taas oo ka kooban annex ah xarunta "Poliglyukin" diiwaanka dareenka. Sababo for daaweynta iyo ka hortaga diyaarinta tani waa sida soo socota:

• stroke cerebral;
• ICP Sare;
• gobolada, taas oo hordhaca ah oo cabitaanno ah ee u tiro badan yahay loo baahnayn;
• cudurka oo ay la socdaan cudurka kelyaha (anuria, oliguria);
• hypertension daran;
• wadnaha,
• cudurada of homeostasis, xinjirowga;
• sii dhiig bax gudaha ah (marka laga reebo - cadaadiska dhiigga ee ka hooseysa 60 mm Hg ..).

daaweynta qiyaasta

Xalka maamulka xididka. Mararka ay dhacdo dhiig la'aan waxaa loo arkaa ba'an, waxaa la ogol yahay isticmaalka daroogada intra-halbowlaha. Heerka maamulka daroogada waxaa si gaar ah goostay oo ay ku xiran tahay xaaladda guud ee bukaan-socodka, heerka qalbigiisa, cadaadiska dhiigga iyo hiimotokiriit.

By dalalka lama filaan ah "Poliglyukin" diiwaanka ku talinaysaa in ay maamusho bolusdose wadada xididka. The dose hal ka mid ah wakiilada in kiisaska noocaas ah looga baahan yahay ma aha in ka yar 400 oo laakiin aan ka badnayn 1200 ml. Xaaladaha qaarkood waxaa lagama maarmaan ah in la kordhiyo qiyaasta daawada ilaa 2000 ml. Haddii waxqabadka BP oo sabab u ah maamulka daroogada keeni karin si caadi ah, kala guurka ah si ay u hordhaca ah ee dhibco daroogada.

Dhiig la'aan weyn, oo u dhiganta 500 ml oo dheeraad ah, iyo sidoo kale ay goobjoog ka ahaayeen anemizatsii daran marka laga reebo isticmaalaya "polyglukin" Xalka waxaa la sameeyaa shubo. Iyadoo tallaabo ka hortag ah si looga hortago in si lama filaan ah inta lagu guda jiro daroogada qaliin ay maamusho si ay u dareerin markii cadaadis uu ku dhacay - jet. Hoos u fiiqan ee cadaadiska dhiigga ilaa 60 mm Hg. Art. iyo hoos u baahan hordhaca ah ee "polyglukin" in mugga a kama weyna 400 mL intraarterially. Ka dib markii performing hawlaha la isticmaalayo ka hortagga this saarka daawada, jidaynayey si looga hortago in horumarinta lama filaan ah.

Xalka waxaa caadi ahaan loo isticmaalaa at uruuray of 6% walax firfircoon, laakiin waxay khusaysaa "Poliglyukin 33" mararka qaarkood. Tilmaamaha loogu isticmaalo waxay muujinaysaa in samaynta la uruuray of dextran waa reagent ah kaabayaal ah marka aad hubinayso waafaqid ee ah qaataha iyo deeq bixiyayaasha.

Marka waxaa lagama maarmaan ah in la baabi'iyo lama filaan ah gubatay, maalintii ugu horraysay qof weyn waxaa maamula 2 kun. Kun si 3. xal ML, waxaa laga codsadaa maalintii labaad ee aan ka badnayn 1.5 kun. Diyaarinta Ml. In kuwa dhacdo lama filaan ah uu yahay mid lagama maarmaan ah in ilmaha laga saaro, waxaa marka hore laga 40-50 hab ml / kg, ayaa maalintii labaad qiyaasta halkii miisaanka jidhka kiilo waa la dhimay ilaa 30 ml. Iyadoo tallaabo ka hortag ah, in la baabi'iyo suurtagalnimada of shock, carruurta soo bandhigo faleebo wadada xididka. Qiyaasta jeclaystay inuu ilmo u dhaxeysa 10 ilaa 15 ml / kg "Poliglyukin" diyaarinta. Tilmaamaha loogu isticmaalo xoolaha, sidoo kale, waxay fursad si aad u codsato daaweynta, ku salaysan sal-dhigida "polyglukin" ah. Ujeeddooyinkan dose xal of 15 ilaa 20 ml / kg ah. Qiyaasta ugu habboon ee daroogada waxaa lagu go'aamiyaa dhakhtarka.

waxyeellooyin

Ka hor inta isticmaalka sheyga "Poliglyukin 'tilmaamaha loo isticmaalo, jawaabaha waxaa lagu dhiirigelinayaa inay dib u eegaan dhibaatooyinka suurogal. Sida caadiga ah dhibaatooyin ha ka kac, iyo jirka ka mid ah bukaanka si fiican u jawaabaan daroogada. Mararka qaarkood waxaa laga dheehan karo oo ah qaab dareen diidmo oo xasaasiyadeed ee lama filaan ah anaphylactic, barar, cuncun iyo furuuruc. In bukaanka qaar ka mid ah, sternum waxaa jira dareen ah riixo, waxaa jira xanuun. waxaa laga yaabaa in qandhada la joogo, dhiig karka hoos, dardargelinta heerka garaaca wadnahaaga. laga yaabaa in aad qabto dhibaatooyin neefsashada, wareer iyo horumarinta acrocyanosis joogaan. Sida iska badiyo natiijo qaadeen load dheeraad ah oo ku saabsan waxyaalaha qalbiga ku jira, waxa uu mamnuucayaa ka badan qiyaasta lagu taliyey macnaheedu yahay "Poliglyukin" diiwaanka. Kiniiniyada iyo daawooyin kale oo bukaan ah waxaa qaadan, carqaladeeyo kartaa tallaabada xalka.

dib u eegista Analogs

medicament bedelay karo "HyperHAES", "Reoglyumanom" ama "Hai-Nadiif ah". Waayo xal loo isticmaalo ujeeddo oo isku mid sida "Poliglyukin" waxaa ka mid ah "Sterofundin", "Reopoligljukin", "Stabizol".

Bedel "Poliglyukin" tilmaamaha loo isticmaalo jidaynayey xaaladaha halkaas oo bukaan-socodka aan ku haboonayn xarunta this. Waayo, bedel loo isticmaali karaa "gelofusin", "Refortan N», «Sorbilakt". Saameyn la mid ah ayaa loo abaalgudi karaan "Albunormom" iyo "Neorondeksom".

Reviews muujinaya in daawada ugu caawisaa baabi'inta dhibaatada. Laakiin tan iyo xaalad kasta waa ka duwan yahay, natiijooyinka uu maamulka waxaa laga yaabaa kala duwan. Inta badan waxay ku xiran tahay xaaladda bukaanka. Dadka halis ah in aadan isticmaalin "Poliglyukin" on iyaga u gaar ah, ay sabab u tahay khatarta ah in maamulka khaldan u maamula maaliyad iyo horumarinta waxyeellooyin.

Its xal function "Poliglyukin" qabata, laakiin daaweynta, iyo sidoo kale fulinta ka-hortagga, waxa aan ahaa wax ku ool ah oo keentay in dhibaatooyin kale, qiyaasta daawada waa in la doortay by dhakhtarka si gaar ah. ku takhasusay oo kaliya maamulo karaa daroogada sida qof caadi ah ay awoodaan in ay si sax ah loo ogaado qiyaasta loo baahan yahay iyo wadada ku habboon maamulka daawada ma noqon doono. qaadasho xad dhaafka ah ee daroogada qatar ku tahay qalbiga, ee sidaas ha u qaadan khatarta, iyo in ay is-Dawada.