Chromatin galmada

Inta badan cudurada carruurta iyo andrology waxaa loo baahan yahay si ay u qabtaan baaritaan hidaha ee bukaanka. Habka Tani waxay u ogolaaneysaa more lagu kalsoonaan karo in la dhiso sababta cudurka ayaa dhexdeenna ka, si ay u soo qaado daaweynta loo baahan yahay iyo si loo ogaado saadaasha horumarinta cudurka.

chromatin Sex - tilmaame muhiim ah horumarinta galmada caadiga ah ee heerka gacanta. Isaga oo ogaanshaha waa lagama maarmaan xaaladaha marka ay timaado cillado ee qaabka taranka dibadeed. Baadhitaanka ayaa la sameeyaa sida ogaanshaha cudurrada uu keeno koromosoomyada ay goobjoog ka ahaayeen horumarinta galmada oo yaraada. Sababta tani u noqon karto maqnaanshaha caadada ee gabdhaha iyo hypoplasia ugxan ama yareeyaan shaqo ee wiilasha.

chromatin Sex markii ugu horaysay la helay by cilmiga Bar John. sannadkii 1949. Samaynta cilmi of unugyada dareenka bisadaha, wuxuu xusay ubucda of formation chromatin xuduntii. Ka dibna, feature muhiimka ah ee unugyada degaaankaaga dumar ah lagu arkay dalka intooda badan oo ka mid ah wakiilo ka socda amarka nuujiya. The unugyada labka ah corpuscles sida lagama helin. jirka Barr waa qayb ka mid ah oo dhan unugyada jirka ee dumarka. Iyo mararka qaarkood waxa ay leedahay nooc ka mid ah appendages ( "diggaagga"). cell degaaankaaga - qaybaha ugu weyn oo jidhka bini'aadamka. Waxaa ka mid ah dhammaan unugyada jirka marka laga reebo gametes ah. Daahfurka ayaa loo ogol yahay in ay ballaariso fikradda ah hababka go'aan galmada ee aadanaha iyo nuujiya.

Joogitaanka meydadka dumar jirka Barr ay sabab u tahay jiritaanka unugyada degaaankaaga, in labada X koromosoomyada. Oo weliba waxqabad uu leeyahay oo kaliya mid ka mid ah. Taasi waa sababta in unugyada haweenka, waxaa had iyo jeer waa jirka Barr ah. Aragtida sidaan ah waxaa sii ogol yahay ogaado cillado horumarinta ee u shaqeeyo. Tusaale ahaan, gacanta saddex koromosoomyada yeelan doonaa laba kubka, afar - saddex, iwm Garashada horumarinta unugyada aan caadiga ahayn waxaa loo isticmaali karaa rag iyo dumarba. Tan iyo 1953, daahfurka this ayaa la isticmaalay si loo ogaado si ballaadhan saxda ah tirada koromosoomyada X in dadka naafada koriinka.

chromatin Galmada ama jirka Barr, iyadoo tiro madow eg a fekrado, saddex xagal ama ul-qaabeeya, oo ku yaalla meel u dhow dusha hoose oo xuub nuclear. Tani firfircoonayn X-koromosoom, kuwaas oo ay dhexroor ka yar tahay 1 micron. Ogaanshaha maydadka Barr in unugyada 10-12% ee daraasadda waxay muujinaysaa a chromatin galmada wanaagsan. wax Research sida caadiga ah waxay u adeegtaa epithelium xabka loogu talagalay (dusha sare colnimada Nabiga), siilka, jiridda timaha iyo dheecaanka amniotic. Haddii tiradaasi kama badna 5%, waxa uu muujinayaa a chromatin galmada xun.

chromatin Sex sababa kala duwan ee nuclei interphase in rag iyo dumarba. Waxaa la xidhiidha qaababka shaqeeya nidaamka taranka iyo qaab-dhismeedka. jirka Barr waa laba nooc: Y iyo X. muuqashadii koowaad waa qayb ka mid ah dhismaha-Y koromosoom oo la ogaado inta badan ragga. Ujeeddooyinkan fluorochrome la isticmaalayo iftiinka ultraviolet. X-chromatin (jirka Barr) - wax aan nooleyn koromosoom X. Its deactivation dhacdaa in toddobaadyada ugu horreeya ee horumarinta uurjiifka iyo waxa lagu kaydiyaa maytosis muddo dheer.

Waa in la ogaadaa in chromatin jinsi ah - waa qaab firfircoon. Waxay kala duwanaan karaan ku xiran xaaladda guud ee jirka iyo Dheef unugyada. Waa sababtaa tan, si ay u qabtaan baadhitaan laguma talinayo inta lagu jiro isticmaalka diyaarinta hormoon, ee maalmood ee ugu horreeya dhalashada ka dib, ka dib markii ay antibiotics iyo daawooyin kale.

Maanta, joogitaanka dhakhtarro chromatin galmo loo ogaado jinsiga hidaha ee ilmaha, laga helay noocyo kala duwan caafimaad ee dysgenesis gonadal iyo hermaphroditism. Assays aqoonsi ee qayb ka ah si weyn loo isticmaalaa in ku dhaqanka foreensiga.