"Daawada methotrexate": dib u eegista cudurka psoriasis. Tilmaamaha loogu isticmaalo

Iyada oo psoriasis wajihi badan maanta. Cudurkaan chronic ma aha nooca faafa, taas oo u muuqato in foomka of finan ama hoolmay on maqaarka. Cudurku wuxuu bilaabi karaa da 'kasta, laakiin sida laga soo xigtay tirakoob, inta ugu badan saamaysaa dadka dhalinyarada ah. On maqaarka bukaanka muuqan dabar qolof in ku yaalaan on suxullada ah, jilbaha, madax. Haddii aad leedahay calaamadahan, waa in aad la tashato maqaarka. Waxa uu sameyn doonaa baadhitaan ah oo qori daaweynta. Mid ka mid ah kuwa ugu badan oo u doonatay daroogada si loo baabi'iyo sababaha cudurka waa "Daawada methotrexate" daawo. Tilmaamaha loogu isticmaalo cudurka psoriasis, dib u eegista - dhammaan macluumaadka aad ka article ugu baran doonaan.

saamaynta

Daawada iska leh kooxda ee wakiilada anti-buro. Waxaa la soo saaray qaab kiniin. Walaxda ugu muhiimsan ee daroogada - methotrexate. Daawada waxaa la soo baakadeeyey ee dhalooyinka of polymer ah kasta 50 kiniin. Daawada hakiyo Avv, unugyada dayactir DNA ay maytosis ah. Inta badan xasaasi u ah daroogada, dhuuxa lafta si dhakhso ah, xiidmaha, kaadi haysta, afka. Sidoo kale, daroogada wuxuu leeyahay sifooyin immunostimulatory. Daawada waxaa maamula afka.

Marka aad hesho xadiga daawo 30 mg si fiican u nuugo ee caloosha. bioavailability celcelis ahaan waa 60%. Haddii aad u hoggaansamaan oo dhan talooyin ku daweyn, qayb ugu weyn ma gelin caqabad dhiig-maskaxda. Qaybta ugu muhiimsan ee daroogada la metabolized beerka, iyo inta kale - in derbiyadii xiidmaha. Saxarrada kelyaha iyo bile. Tallaabadan waxaa Eebay daroogada "MTX". Reviews for bukaanka psoriasis hadhay ee ugu wanaagsan.

Tilmaamayaasha iyo sababo

Daawada waxaa lagu qori karaa cudurrada soo socda:

• leukemia lymphoblastic ba'an oo aan Hodgkin-ee lymphoma,
• buro trophoblastic ;
• mycosis fangas daran;
• stage chronic cudurka psoriasis,
• rheumatoid arthritis, haddii dhamaan daweynada kale ma siin saamayn togan.

sababo:

• uurka;
• nuujinta,
• cudurada of beerka iyo kelyaha,
• xanuunada hematological;
• HIV,
• cudurada faafa;
• da ilaa 3 sannadood,
• Diidmo in qaybaha ah;
• Caloosha iyo boogaha dyspepsia;
• ascites;
• ulcerös kolit;
• turqo.

Ka hor inta bilowga ah ee geedi socodka daaweynta loo baahan yahay in si fiican loo baaro oo dhan sababo ah in ay "Daawada methotrexate" daroogada. In psoriasis, dib u eegista ah oo ku saabsan daawada muujinaya in kiniiniga caawisa wakhtiga gaaban in laga takhaluso oo ka mid ah cuncun iyo finan maqaarka ah.

Qiyaasta iyo badinta

daawada loo qaato afka on nidaamka u gaar ah, kaas oo ku meelaynayaa takhasus ah oo ku saleysan darnaanta ee geedi socodka. In wakiilka psoriasis loo isticmaalo laga bilaabo 10 ilaa 25 mg halkii todobaad. in la kordhiyo qiyaasta waa in ay si tartiib ah. Marka dhaqdhaqaaqa wanaagsan ee cudurka hoos heerka maalin kasta. koorsada daawada qaadataa dhowr bilood. Waxaa lagu talinayaa in ay qaataan kiniinnada oo aroortii ah iyo biyo qaar ka mid ah cabbaan. Marar badan Xirfadleyaasha haragga ee u qoraan dadka kiniiniga "Daawada methotrexate" in psoriasis. Reviews muujinaya in daawada waa mid aad waxtar u leh cudurrada this.

Asal ahaan daroogada si fiican loo dulqaatay. Inta badan kaliya kordhisaa-fiirsashada ee plasma. In sida xaalad waa in la isla markiiba maamula fiqiira (calcium folinate) saacad sumowga ugu horeysay. Weli u baahan yihiin si ay u qabtaan alkalinization kaadida iyo fuuq ee jirka. Sidoo kale ka hor maamulka kasta oo daroogo in lagu go'aamiyo kaadida RN ilaa tirooyinka walax ee plasma ah ma gaaro heerka of 0.05 pmol / l, bixinta pH kaadida kor ku xusan 7.

Dhexgalka daroogooyinka kale

Ma talinayaa in daawo la daawooyinka soo socda:

• coumarin iyo indandione taagayo,
• qalabka loo isticmaalo in lagu daaweeyo turqo,
• "Amiodarone";
• folatsoderzhaschie daroogada;
• "Neomycin";
• daawooyinka, Illaa;
• "Cytarabine";
• xabagta dinitrogen.

Co-maamulka keeni doontaa in sare oo plasma waxaa loola jeedaa "Daawada methotrexate" (jawaabaha in psoriasis show in lagu daaweeyo cudurrada maqaarka noqon kartaa si deg deg ah oo ku filan). Taasi waxay keeneysaa khatar ah waxyeellooyinka.

Uurka iyo nuujinta

daroogada waxay leedahay guryaha teratogenic in keeni kartaa dhimasho oo ka mid ah ilmaha caloosha iyo cuuryaannimo lagu dhasho. Haddii inta lagu guda jiro daawaynta naagtii uuraysatay, waa in aad kor u arrinta joojinta uurka ay sabab u tahay khatar sare si ay ilmaha caloosha ku. Gudbinta macnaheedu waa caanaha naaska, si aadan u siin karto ilmahaaga inta lagu jiro daaweynta.

Kuwa soo socda waxyeelo laga yaabaa in inta lagu guda jiro daawaynta:

• anemia;
• Torombositobiiniya;
• lalabo,
• matag,
• anorexia;
• stomatitis;
• yiridka,
• dhiigbaxa caloosha;
• wareer;
• hepatitis ba'an, fibrosis iyo cirrhosis of beerka,
• pankreatit;
• dawakhsanaan;
• conjunctivitis;
• aragti cawlan,
• pneumonia,
• encephalopathy;
• renal failure;
• nephropathy, iyo calaamado kale.

Haddii ay dhacdo in calaamadaha xun waa in la tasho dhakhtar, kuwaas oo edbin doonaa looga baahan yahay maalin walba of daroogada "Daawada methotrexate" ah. In psoriasis, dib u eegista dhakhaatiirta ayaa muujinaya in daroogada ayaa muujinaysa natiijooyin wanaagsan marka loo isticmaalo qiyaasta ugu yar.

ganaaxyada

Dejinta waa in lagu keydiyo ee heerkulka jirin sare ka badan 25 digrii oo engegan oo ay gaaraan carruurta. Nolosha shelf ee daroogada waa 3 sano. Marka ay dhamaato muddada hirgelinta waa in aanay noqon hab used. The qoro daawo farmashiyaha.

Wuxuu magacaabaa daroogada a in uu leeyahay qaab-dhismeedka kiimikada adag oo tiro badan oo ah waxyeelo, dhakhtarka kaliya leh waayo-aragnimo, aqoon qorshayaasha ay codsiga in psoriasis. Ka hor inta daaweynta, dhakhtarku waa inuu u sheego qofka bukaanka ah ku saabsan oo dhan tilmaamo iyo sababo, calaamadaha sarkhaan. Sidoo kale u yeelaan dhiiga iyo kaadida kiliinikada. daroogada ayaa saamayn ku shaqada habdhiska dhexe. Sidaa darteed, inta lagu jiro mudada daaweynta laguma talinayo in la wado baabuur ama mishiino aadka u halista ah.

daaweynta "methotrexate" Psoriasis la sameeyaa waa kuwo ku adag. khubaro Guest soo jeedinaynaa in si loo gaaro dhaqdhaqaaqa wanaagsan ee cudurka waa suurtogal, haddii xaq u leedahay in la horumariyo nidaamka ka mid ah therapy.

Drug "Daawada methotrexate-Ebewe" - waxaa loola jeedaa bedel ku for "Daawada methotrexate"

daroogada waxaa laga heli karaa foomka of xal huruud ah ama cad la isku duro xididka iyo muruqyada dhexdooda at dose oo ah 1 iyo 5 ml. walax ugu weyn ee wakiilka ka kooban yahay methotrexate. Waxaa loola jeedaa koox ka mid ah wakiilada antitumor in loo tixgeliyaa in antimetabolites iyo analogs ee folic acid. Sidoo kale, daroogada hagaajinaysaa habka difaaca jirka. Iyadoo hordhaca ah ee daroogada intramuscularly arkay fiirsashada maximal ee plasma ka dib markii 1 saac.

Tilmaamayaasha iyo sababo

Waxaa loo adeegsaday in noocyada halista ah ee cudurka psoriasis. Waxay ka caawisaa si loo baabi'iyo cuncun, fuqaya iyo raaxo la'aan.

sababo:

• kelyaha iyo yaridu cagaarshowga ;
• khamriga,
• xanuunada ku hematopoiesis;
• HIV,
• cudurada faafa;
• uurka;
• naas-nuujinta.

Bilowga habka daaweynta waa in ay tixgeliyaan oo dhan sababo in loo isticmaalin lacagaha ", Daawada methotrexate Ebewe" in psoriasis. Reviews of dhakhaatiirta iyo bukaanka ay u muujiyaan a daawooyinka ka iman kara sare ah oo lagu daweeyo cudurka this. medicament waxaa iska kaydiyaa caruurta heerkulka a lahayn ka badan tahay 30 darajo. farmashiyaha ayaa la sii daayay oo keliya by qoro. Qiyaasta abuurayaa takhasus u leh shakhsiga ku saleysan. Xalka waxaa maamula intramuscularly ama faleebo, si tartiib ah.

Drug "Daawada methotrexate": dib u eegista cudurka psoriasis

In daaweynta cudurro badan, shalalka oo ay ku jiraan psoriasis, caadi ahaan loo isticmaalo nudaha. Sidaas darteed, daroogada wuxuu leeyahay sifooyin jirka iyo siinayaa heerka la doonayo. Waxay leedahay daawo cytostatic saamayn "MTX". Reviews u fiican yihiin psoriasis, daroogada siinayaa horumar la arki karo. Waxay ka caawisaa si ay u joojiyaan habka qaybinta unugyada maqaarka. Sababo la xiriira joogitaanka saameynta badan kooxda in ay is-Dawada laguma talinayo. Qorshaha qofka bukaanka ah uu yeesho dermatologist la darnaanta psoriasis iyo sifooyinka gaarka ah ee u shaqeeyo.

Asal ahaan daroogada ay maamusho isku dhafan oo daawooyinka kale ee caawin ka saar calaamadaha cudurka psoriasis. dib u eegista wanaagsan la maqli karaa oo ku saabsan kharashka daawada. Daawada waxaa laga heli karaa in qiimaha oo laga heli karo qaab kiniin iyo xal. Qiimaha qiyaas farmasiyada of Russia waa 600 rubles halkii pack.