Hypogonadism Hypogonadotropic: calaamadaha, daaweynta

Sida caadiga ah, hypogonadism hypogonadotropic la xidhiidha horumar xubnaha galmada iyo sifooyinka galmada sare. sarrifka baruurta iyo protein in cudurada ayaa sidoo kale ku xad, kaas oo keena cayilka, cachexia, cudurada of nidaamka lafaha iyo cillad wadnaha ka mid ah.

By dhakhtarro jidka daweeyo?

Waa in la ogaadaa in lab kala duwan iyo hypogonadism hypogonadotropic dhaddig.

Cilad-iyo daaweynta cudurka waxaa lagu fuliyaa si wadajir ah endocrinologists, dhalmada iyo haweenka, endokrinolongami haddii bukaanku waa qof dumar ah, iyo andrology, haddii bukaanku waa - nin.

The salaysan daaweynta ee therapy hormone. Haddii la doonayo qaliin lagu muujiyey, qalliinka caag ah.

Sida uu cudurku uga lagu tilmaamay?

Hypogonadism noqon kartaa hoose iyo kuwa sare. Foomka waxaa aasaasiga ah ee unugyada Testicular xadgudub shilalka ka shaqeynayaan sabab u ah cillad ku xiniinyaha. at koromosoomyada ugu aan caadi ahayn heerka cadhaysiiyaan hypoplasia ama Testicular aplasia nudaha, kaas oo lagu muujiyey in dheecaan ka maqan ama aan ku filnayn ee androgens ee ay wax soo saarka ee formation ka buuxaan xubnaha taranka iyo sifooyinka galmada sare.

hypogonadism Hypogonadotropic ragga waxaa lagu qeexay in infantilism derjada.

foomka dugsiga sare waxaa keena xadgudub ku ah qaab-dhismeedka qanjirka pituitary ee, yaraynta shaqo gonadotrophic ama guuldarro xarumaha ay hypothalamic in ay leeyihiin saamayn on qanjirka pituitary iyo xeer u dhaqdhaqaaqa. Cudurku wuxuu ku muuqata in xanuunada dhimirka.

foomka Labada hoose iyo kuwa sare waxaa laga yaabaa in lagu dhasho ama heleen. cudurradana laga yaabaa in ay gacan ka dhalmo la'aan lab in 40-60% ee kiisaska.

Sababaha cudurka ragga

xaddi Low of androgens waxaa keeni kara hoos u dhac ku yimid qaddarka lacagta ee hormoonnada soo saaray xaalad cudur ama naftooda, hypothalamus xadgudub iyo shaqada pituitary xiniinyaha.

By etiology muujinta aasaasiga ah cudurka la oran karo waa:

• qanjidhada horumar lagu dhasho galmada, taas oo uu dhacaa marka ay cilado hidaha ee qof,
• aplasia ee xiniinyaha.

sababa xasiloooni ka mid noqon kara:

• xadgudub ka soo jeeda Testicular;
• gaadhista walxaha sunta ah,
• chemotherapy;
• saamaynta dareeraha ku salaysan organic, nitrofurans, sunta cayayaanka, khamriga, tetracycline, oo ku salaysan daawooyin hormone in qaadasho sare, iwm.,
• dabeecadda faafa cudurka (mumps, jadeecada, orchitis, kiishka);
• joogitaanka bukaanka shucaaca,
• helay cudurada of xiniinyaha,
• maroojinta xarigga spermatic;
• xidhmo ah xiniinyaha,
• habka Atrophic qalitaanka ka dib,
• excision of Sheelada ka,
• qalliinka ee xiniinyaha ah.

In hoos hypogonadism koowaad ee heerka androgens in dhiiggiisa la soo arkay. Horumarisa jawaab magdhawga oo ka mid ah qanjidhada adrenal, waxay kordhisaa-soo-saarka ee gonadotropins.

Si ay u sameeyaan cudurada sare hypothalamus hogaanka iyo pituitary (geedi socodka bararka, burooyinka, cudurada qas of horumarinta uurjiifka ka vascular).

Kor u qaado horumarka of hypogonadism sare kartaa:

• adenoma pituitary, guud ahaan hormone koritaanka;
• hormone adrenocorticotropic (cudur Cushing ee);
• prolactinoma;
• cillad qanjirka pituitary ama hypothalamus qalitaanka ka dib,
• geedi socodka gaboobaya, kaas oo keena hoos u dhac of testosterone ee dhiigga.

In foomka sare calaamadeeyay yareynta gonadotrophins, taasoo keentay in soo saarka antiandrogen hoos u dhac by xiniinyaha.

Nooc ka mid ah cudurka, waxay saamaysaa ragga, waa in la yareeyo wax soo saarka ee shahwada la index testosterone caadiga ah. Marar dhif ah waxaa jira hoos u dhac in heerarka testosterone ee heerka caadiga ah ee shahwada.

Symptomatology cudurka ragga

hypogonadism Hypogonadotropic ragga ayaa daliilka ay kiliinikada. Waxaa sababa da'da bukaanka iyo heerka kaafi antiandrogen.

Haddii xiniinyaha waxaa lagu dhuftay wiilka ka hor inta qaangaadhnimada, ka dibna waxa la aasaasay syndrome caadiga ah. Lafaha sidaas noqdo sineyn waaweyn. Tan waxa u sabab u dhac ku lafoobid ee aaga koritaanka. Garabka iyo xabadka ayaa sidoo kale ka danbayso in horumarka, addimada waa muddo dheer, murqaha lafaha waxaa si liidata horumariyo.

Obesity lagu ogaan karaa nooca dumar, gynecomastia, gipogenitalizme in lagu muujiyay in guska a size yar yar, ma qabsatay in Xiniinyaha, hypoplasia Testicular, horumar ah ee 'prostate', maqnaanshaha timaha degaanka gumaarka, horumar ah ee dhuun ah, midab sare oo cod.

In muujin sare ee cudurka inta badan lagu arkay miisaanka jidhka sare, shaqo kiliyaha adrenal kacsantahay, hawlgalka thyroid oo yaraada.

Haddii shaqo Testicular waa la dhimay dib marka ay baaluqaan, calaamadaha cudurada sida hypogonadism hypogonadotropic, la ogan karo taagta daran.

Kuurgalay ifafaale soo socda:

• hoos ka mid ah xiniinyaha,
• yar timaha jirka wajiga iyo jidhka;
• luma barti maqaarka iyo khafiifinta;
• hoos shaqada galmada;
• xanuunada autonomic.

Hoos u dhaca size Testicular waxaa mar walba la xiriira soo saarista shahwada hoos. Taasina waxay keentaa in dhalmo la'aan, waxaa jira dhaca ah sifooyinka galmada sare, calaamadeeyay tabar-dari muruq, daal.

Garashada hypogonadism ragga

Cilad la sameeyey by anthropometry, kormeerka iyo taataabasho ee xubnaha taranka, qiimaynta astaamaha caafimaad oo baaluq degree.

Baaritaanka X-ray caawin doonaa si ay u qiimeeyaan da'da lafta. Si loo go'aamiyo u damaysay ee densitometry macdanta lafaha loo isticmaalo. Marka x-rays ee turcica Sella go'aamiyo ay le'eg tahay iyo joogitaanka kasoobaxyo.

Qiimaysay da'da lafta u oggolaanaysa in muddo ah lafoobid gacanta si wadajir ah iyo curcurka si loo ogaado goorta bilawga qaangaadhnimada. Waxaa waa in ay tixgeliyaan suurtagalnimada ee hore ah (bukaanada u dhashay koonfurta) iyo ka dib (ee loogu talagalay dadka bukaanka ah ku dhashay woqooyi) lafoobid, iyo sidoo kale xaqiiqada ah in cudurka Osteogenesis waxaa sababi kara arrimo kale.

Research on shahwada shaybaar oo noo ogolaadaa in ay ku hadlaan oo ku saabsan xaaladaha sida nitrogen ama oligospermia.

Tilmaamay by content ee hormoonnada sida:

• gonadotropins galmada;
• total iyo testosterone free ;
• farabadan oo hormone;
• GnRH;
• hormone antimyullerovsky;
• prolactin;
• estradiol.

Marka foomka hoose ee index cudurka of gonadotropins dhiigga ku kordhay iyo sare - hoos. Mararka qaarkood heerka waa in xeerarka qaybin ah.

Determination of estradiol serum loo baahan yahay marka feminization astaamaha iyo muujinta sare ee cudurka in ay dhacdo burooyinka ee xiniinyaha saara estrogen, ama burooyin in qanjidhada adrenal.

Index content ee ketosteroids kaadida waxaa laga yaabaa in si caadi ah ama la dhimay. Haddii aad ka shakisan tahay joogitaanka falanqaynta Klinefelter syndrome koromosoom muujiyay haysta.

biopsy Xiniinyaha ma awoodo inuu bixiyo macluumaadka loogu talagalay cudurka saxda ah.

daaweynta

Daaweynta hypogonadism hypogonadotropic waxaa loogu talagalay baabi'inta sababta ugu weyn ee cudurada ka. Ujeedada therapy been in hawlaha ka hortagga in ay gacan caadi ah ee horumarinta galmada, hoos ku xiga ee unugyada Testicular Testicular baabi'iyo dhalmo la'aan. Therapy la sameeyaa iyada oo ay kormeerayaan of the kaadimareenka iyo endocrinologist.

Sidee reebay hypogonadism hypogonadotropic in dadka? Daaweyntu waxay ku xidhan dhawr arrimood:

• foomka caafimaad ee cudurka;
• adkaanta cillad hypothalamus oo ah, qanjirka pituitary iyo habka taranka,
• helitaanka coexisting heley;
• wakhtiga dhacdo cudurka;
• da'da bukaanka.

Daaweynta xaaladaha dadka waaweyn waa in la saxo heerarka androgens iyo baabi'iyo cillad galmada. Dhalmo la'aan, taas oo ka kacay oo ah qaab hypogonadism dhasho, daaweynta ma noqon karo.

In the case of noocyada aasaasiga ah ee aan caadi ahayn ee lagu dhasho ama cudur helay at unugyada hormoonada jidhka ammaanka ee xiniinyaha isticmaalo kiciya. Boys waxaa lagu daaweeyaa wakiilada ku jirin hormoonno, iyo bukaanada qaangaarka ah - daroogada ku saleysan hormone (antiandrogen iyo gonadotropins in yar ka qaataan).

Haddii ay maya tahay Testicular function gurmad muujiyay therapy bedelka antiandrogen iyo testosterone. Qaadashada hormoonnada waxaa lagu fuliyaa nolosha oo dhan.

Marka foomka sare ee cudur ee carruurta iyo dadka waaweyn u baahan yihiin in ay isticmaalaan gonadotropin hormone. Haddii loo baahdo, ay weheliso hormoonnada jinsiga.

Sidoo kale muujiyay waa daaweynta dib u soo celinta, iyo jimicsiga.

Operation qaba cudurka waa in uu xubin ugxan la cryptorchidism, loo isticmaalo qalliinka caag ah ee guska dhacsan. Iyada oo loo dalxiis tago ee la isku qurxiyo qastiyey dardaro tallaalmid ukunta ku salaysan (in maqnaanshaha testis undescended in saabka caloosha).

Qalliinka waxaa loo isticmaalaa marka la isticmaalayo farsamooyin microsurgical, oo ay la socdaan ay gacanta of habka difaaca jirka, heerarka hormone, iyo sidoo kale xubin tallaalay.

Inta lagu jiro daaweynta nidaamsan hoos la'aan antiandrogen, dib horumarinta dabeecadaha galmada sare, awoodba qayb ahaan la dhimay, daliilka hoos osteoporosis iyo da'da lafta maray.

Sidee cudurka dumarka

hypogonadism Hypogonadotropic dumarka waxa lagu gartaa horumar ah ee shaqada galmada iyo qanjiro ugxansiduhu kordhay. foomka lagu dhasho Primary ay sabab u tahay dhaawac horumar ama ugxan sidaha muddada dhalaanka.

Waxaa hoos u wax soo saarka ee hormoonnada jinsiga, taas oo dhirfinaya kordhiyo heerka gonadotropins, taas oo kicin ugxan.

In falanqaynta ee heerka sare ah ee hormoonnada in kicin kiishashka iyo lutein, iyo sidoo kale heerarka hooseeya ee estrogen. Heerka hoos u estrogen sababa atrophy ama xubnaha taranka dhacsan dhaddig, qanjirada caanaha, maqnaanshaha caadada.

Haddii shaqo ugxansiduhu waxaa daciif ah ka hor inta qaangaadhnimada, ka dibna waxaa jira la'aan ah sifooyinka galmada sare.

hypogonadism Hypogonadotropic in haweenka ee aasaasiga ah sida ku cad shuruudaha soo socda:

• cudurada lagu dhasho ee heerka hidaha;
• hypoplasia dhasho ugxan,
• geeddi socodka faafa (Syphilis, Qaaxada, Mumps, cindiga, ka saarida qalliinka ugxan);
• guuldarro ee dabiiciga ah, shalalka,
• syndrome, feminization Testicular ;
• ugxan polycystic.

hypogonadism hypogonadotropic Sare ee haweenka ku dhacaa cudurada ka mid ah pituitary iyo Hypothalamus. Waxaa la kala duwanaayeen joojinta hooseeyo content ama dhamaystiran oo-soo-saarka ee gonadotropins nidaaminaya function ugxansiduhu. Nidaamkan waxaa keena barar ka mid ah gobolka maskaxda. Cuduradan waxay ku leeyihiin saameyn waxyeello iyo waxaa weheliya hoos u dhac in heerka gaadhista ee gonadotropins in ugxan.

Sidee cudurada sida hypogonadism hypogonadotropic dumarka, iyo uurka? horumarinta Dacdarrada intrauterine ilmaha caloosha ayaa sidoo kale saamayn kara dhacdo ee cudurka.

Calaamadaha dumarka

calaamadaha Bright muddada carruur-dhalista - xadgudub ku tahay caadada, ama la'aanta oo dhanba.

Heerka hoose ee dumarka ee keenta in horumar ee xubnaha galmada, qanjirada caanaha, xadgudub dhigaalka ee timaha jirka baruurta iyo macaluuli.

Haddii uu cudurku waa lagu dhasho ee dabiiciga ah, sifooyinka galmada sare ma muuqan. Haweenka ayaa sheegay in joogitaanka a miskaha cidhiidhi iyo badhida guri.

Haddii cudurka ka hor qaangaadhnimada dhacay, dabeecadaha galmada in u muuqday in ay weli ku badbaadiyey, laakiin bil kasta joojiyo atrophy unugyada taranka.

adeega waa

Hypogonadism marka uu jiro hoos u dhac in heerarka estrogen iyo heerarka siyaadiyaa gonadotropins. Iyada oo ultrasound muujiyey hoos-galeenka size cudurka formation ostepoporoz iyo dib u dhac of lafaha.

daaweynta cudurada dumarka

Sidee reebay hypogonadism hypogonadotropic dumarka? Daaweynta ku lug Daaweyn laguugu beddelo. Haweenka qoondeeyey in ay qaataan daawada iyo hormoonnada jinsiga (estradiol etinylesttriadiol).

In the case of Bilowgii hore ee caadada kuu qori-piller ka kooban estrogens iyo progestins, iyo diyaarinta "Triziston", "Trikvilar".

Oo macnaheedu yahay "Klimov", "Trisekvens", "klimonorma" qoro bukaanka ka dib 40 sano.

daaweynta hormoonka waa u in shuruudaha soo socda:

• buro kansar ee naasaha iyo xiniinyaha,
• wadnaha iyo xididdada dhiigga cudurada;
• kelyaha iyo beerka,
• thrombophlebitis.

ka hortagga

cudurada sida hypogonadism hypogonadotropic, ayaa saadaal wanaagsan. Ka Hortagga waa waxbarashada caafimaadka oo ka mid ah dadweynaha iyo la socodka haweenka uurka leh, iyo sidoo kale hawlaha caafimaadka.