"Lorista" (kiniin): tilmaamaha loo isticmaalo, dhigooda dhabta ah

Suuqa dawooyinka waa hodan la daawooyin si hoos loogu dhigo cadaadiska dhiigga. iyaga ka mid ah waa ku Doodeen receptor angiotensin enzyme.

nooc ka mid ah daroogada

Daawo "Lorista" helaya iyada oo foomam dhowr: a diyaarinta hal qayb "Lorista" noocyada la isku daray "Lorista H" iyo "Lorista soo taago" taas oo ku kala duwan qiyaasta walxaha firfircoon. foomka Bicomponent diyaarinta leeyihiin dhaqdhaqaaqa antihypertensive oo u hantidaan saamayn lagu durayo.

Qaab-dhismeedka

Kiniiniga "Lorista" samaynta monocomponent waxaa lagu heli karaa saddex qaadashada ee ka kooban walax firfircoon losartan potassium 12.5 mg, 25 mg, 50 mg. Sida qaybaha kaabayaal ah loo isticmaalo, iyo pregelatinized galleyda, cellulose mikrokristallin, isku dar ah ee lactose iyo cellulose, aerosil, milmahayn magnesium. qaadashada daahan Film of 25 mg ama 50 mg of potassium losartan ka kooban hypromellose, Rusheyn kartaa, tones propylene, titanium dioxide, iyo 12.5 mg for qiyaasta loo isticmaalaa xitaa dheeh huruud quinoline.

Kiniiniga diyaarinta "Lorista H" iyo "Lorista soo taago" ka kooban yihiin xudunta u ah oo qolof ah. core wuxuu ka kooban yahay laba qaybood oo firfircoon: Losartan potassium 50 mg (foomka H) iyo 100 mg (noocyada ND) iyo hydrochlorothiazide 12.5 mg (foomka "N") iyo 25 mg (for "taago" qaabka). Si ay u sameeyaan isticmaalka xudunta u ah qaybaha dheeraadka ah sida noqde pregelatinized, cellulose mikrokristallin, lactose, milmahayn magnesium.

Kiniiniga "Lorista H" iyo "Lorista soo taago" daahan filim kooban hypromellose, macrogol 4000, dheeha huruud quinoline, titanium dioxide iyo Rusheyn kartaa.

Sida falalka daroogada

Wakiilka antihypertensive isku daro ( "Lorista" diyaarinta) ee buuggan wuxuu qeexayaa tallaabada pharmacological ee qayb kasta oo firfircoon.

Mid ka mid ah sinji waa losartan, ku simaha sida antagonist xulashada of angiotensin nooca enzyme 2 receptors dhismeedka nonprotein.

Studies sameeyay giisa iyo xoolaha, ayaa lagu ogaaday in saamaynta losartan iyo metabolite carboxyl ay waxaa loogu talagalay is hortaagaan saamaynta angiotensin nooca angiotensin 1 receptors. Tani waxay shidaa renin ee plasma dhiigga iyo sababa hoos u dhac ku fiirsashada aldosterone joogo ee serum dhiigga.

U keenida heer sare ah nooca angiotensin 2 receptors losartan shidaa enzyme this, waqti isku mid ah aysan waxba ka beddelin hawlgalka kininazy nooca enzyme 2 ku lug-shiid ee bradykinin.

tallaabada of qayb firfircoon ee diyaarinta "Lorista" golleeyahay in lagu yareeyo tirada guud ee iska caabin ah durugsan sariirta vascular, cadaadiska gudaha weelashii wareegga pulmonary, afterload, bixinta saamayn lagu durayo.

Losartan ka hortagtaa u kaca ee kordhay bahal ee muruqa wadnaha, waxay kordhisaa iska caabin ah si ay shaqada jirka ah ee jidhka bini'aadamka, taas oo ay jirto wadnaha chronic.

codsiga Daily of dhoos keli ah losartan sababaya hoos u dhac joogto ah ee sare (systolic) oo hoos u cadaadiska (diastolic) dhiigga. Inta maalinta sarkhaansan yihiin walxaha waa la fuliyay gacanta uniform of cadaadiska dhiigga iyo saamaynta antihypertensive ku beegan tahay laxanka dabiiciga ah kirkeydiyanka. Yaraynta cadaadiska waqtiga xiritaanka shaqeeyaa losartan qiyaasta dhacdaa at 80% hawlaha ugu sarreysa ee qayb firfircoon marka la barbar dhigo. In daaweynta medicament ma saamayn on garaaca wadnaha, iyo joojinta soo dhaweynta aan loo horumariyo calaamadaha bixitaanka of daroogada. Saamayntii losartan codsan jidhka lab iyo dhaddig oo da 'walba leh.

qayb ka mid ah ay tahay marka la isku daro tallaabada of hydrochlorothiazide sida lagu durayo a, a thiazide la xidhiidha nuugista oo yaraada ee atammada chlorine, sodium, magnesium, potassium, iyo biyo ku yaalla kaadida hoose dib plasma dhiigga nephron distal kelyaha ah. walaxda wanaajisaa xafidista ra'iyi calcium iyo uric acid. Hydrochlorothiazide muujiyaan guryaha antihypertensive ay sabab u tahay ballaarinta arterioles ah. saamayn lagu durayo bilaabo 60-120 daqiiqo ka dib iyo saamaynta ugu durayo socdaa 6 ilaa 12 saacadood. saamayn aan fiicnayn antihypertensive daaweynta daroogada dhacdaa 1 bil gudaheed.

maxaad ka codsan

Drug kiniin "Lorista", diiwaanka soo jeedinay:

• daweynta hypertension, taas oo daaweynta marka la isku daro waa la muujiyey,
• si loo yareeyo suurtagalnimada of cudurada nidaamka wadnaha iyo tirada dhimashada ee hypertension iyo isbedel bahal ee ventricle bidix.

Qadarka Qaadashada

daroogada waxaa loogu talagalay maamulka afka. Cunista cunto saameyn ah kuma laha tallaabo ah ee daroogada. Kiniinka "Lorista" cadaadiska lagu dari laga yaabaa in la antihypertensives. Cunista cunto saameyn ah kuma laha tallaabo ah ee daroogada.

In diyaarinta "Lorista" (kiniin) tilmaamaha loogu isticmaalo waa hal qayb talooyinka kacmaha qaabka, "H" iyo isu-gaynta "taago". Maxaa yeelay, dhammaan noocyo dose hore iyo dayactirka medicament at cadaadis kacsantahay sida 1aad 1 kiniin ah hal mar maalintii. Saamaynta ugu badan ee hoos u dhac cadaadiska lagu arkay 3 wiig ee daaweynta ka dib. Si loo gaaro saamayn weyn, ogol yahay in la kordhiyo qiyaasta maalin kasta "Lorista H" in 2 kaniini oo ah halkii 1 dhaweynta. Tirada Saacadaha ugu badan kiniin qiyaasta 50 / 12.5 mg ah ee 2 gogo '.

Haddii saamayn ku filan daweynta qaadashada medicament ah "Lorista H" maqan yahay, qorayaasha ah "Lorista soo taago" kiniin. on guide qalab ka mid ah macluumaadka ku saabsan tirada ugu badan qiyaasta weyn (100/25 mg) maalin kasta, taas oo aan ka badan 1 kiniin ah.

By yareynta mugga dhiigga wareegaya weelasha lagu jiro daaweynta leh qaadasho sare ee diuretics dose maalin kasta hore ee 25mg losartan isticmaalo waqti. Sidaa darteed, sida a antihypertensives therapy ayaa suuragal ah keliya ka dib markii diuretics oo caadi ka saarida mugga dhiigga.

In diyaarinta "Lorista" (kiniin) edbinta kuma jiraan macluumaad ku saabsan baahida loo qabo in la qabsato qiyaasta dadka bukaanka ah dadka waayeelka ah iyo dadka lagu kelyaha, ama kelyaha la ansixin kariyaatiniin ee 30 ilaa 50 ml halkii daqiiqo ah.

Si loo yareeyo khatarta ka mid ah nidaamka wadnaha-vascular iyo tirada dhimashada ee bukaanka qaba dhiig-karka halbowlaha iyo isbedel bahal ee ventricle bidix ee qiyaasta laga bilaabo caadiga ah ee maalin walba losartan maamula at 50 mg halkii dose hal. Haddii natiijada aan la gaari by yareynta dhiig-karka ee qiyaasta hore waa in la kordhiyo 100 mg losartan, taas oo suurto gal ah marka la isticmaalayo 2 "H Lorista" diyaarinta kiniin ama kaniiniyo 1 "Lorista soo taago" maalin kasta ee ka mid ah qayb.

waxyeellooyin

qaar ka mid ah Bukaan-socodka suurto gal ah in Waxyeellooyin ka daaweynta sida wakiilka hypotensive. Marka la isticmaalayo "Lorista" diyaarinta (kiniin) oo isticmaalaya edbinta ka mid ah liiska waxyeelo la xidhiidha hababka kala duwan ee u shaqeeyo.

Saamaynta nidaamka dhexe ee habdhiska muujiyey by madax xanuun, wareer systemic iyo non-systemic, hurdo la'aan, daal, xanuunka dhanjafka.

Marka saameynta on nidaamka wadnaha iyo daroogada sababa orthostatic hypotension, uurkuna waa, tachycardia, caabuq vascular dose la xiriira.

Action on habka neefsashada muuqataa qufac, caabuq in aagga sare ee neefsashada, pharyngitis, barar xabka sanka.

nidaamka dheefshiidka waxaa hakad qaab shuban, dyspepsia, lallabo, matag, calool xanuun, hepatitis, shaqada beerka aan caadi ahayn, marka in la beddelo waxqabad ee falgalka beerka iyo bilirubin.

On nidaamka muruqyada ficilka muujiyey myalgia, xanuunka dhabarka, arthralgia.

On xubnaha dhiig-sameynta ee saamayn anemia muujiyey iyo purpura.

Change iyo shaybaarka koobin, lagu gartaa hyperkalemia, kordhay plasma dhiig heerka hemoglobin, kariyaatiniin, hiimotokiriit, HOL.

action waxaa la socon kara by dareen diidmo oo xasaasiyadeed, cudurka urtikaria muujiyey, pruritus, shoog, angioneurotic barar wajiga, ee qoorta, xabadka iyo qaybaha sare ee xubnaha ka durugsan.

sababo

Ma aha qof kasta waa la daaweyn karaa by daroogada "Lorista". Tilmaamaha loogu isticmaalo aan lagula talinayaa in ay ka dalban qalab ee anuria muujiyay kelyaha aadanaha marka ansixin kariyaatiniin ka yar 30 mL halkii daqiiqo.

Sababo dhoweynta la hyperkalemia hypokalemia madax adkaadeen qabto dheelitirka biyaha ee jirka intii lagu therapy la qaadasho sare ee diuretics muujiyay beerka aadanaha, cadaadis kacsantahay, deficiency of enzyme lactase ah, dulqaad in sonkorta iyo galactose, uurka, Naas-nuujinta carruurta iyo dhallinyarada ka yar 18 sano jir .

Daaweynta la "Lorista" (kiniin) edbinta mamnuucayaa diidmo in xeryahooda sulfonamide ee taxanaha ah, si losartan walax, hydrochlorothiazide ama qaybaha kaabayaal medicament ah.

digniin loo baahan yahay marka loo isticmaalo in bukaanka qaba dheelitirka biyaha-elektrolytka oo yaraada ee dhiiga marka ay jiraan calaamadaha alkalosis hypochloremic, content low ah ee atammada sodium, potassium, magnesium iyo sare ee udhigo calcium ee jirka aadanaha.

Cidhiidh laba geesoodka ah ee halbowlaha kelyaha ama cidhiidhi ah halbowlaha kelyaha hal, diabetes, heerarka sare ee uric acid ee plasma dhiigga, dhigaalka ee urate ku jira laabatooyinka ee, joogitaanka ee dareen diidmo oo xasaasiyadeed ee la soo dhaafay in ay daroogada in la xakameeyo angiotensin diinta enzyme, neefta bronki, cudurada habka dhiig waa sababta ah in ay si taxaddar leh isticmaalka daawooyinka antihypertensive.

Features of codsiga

Inta lagu guda jiro daawaynta "Lorista" (kiniin) tilmaamaha loo isticmaalo dheeraad ah u ogolaanaya qaadashada antihypertensives kale. Waayo, dadka waayeelka ah ma aha doorasho gaar ah oo qiyaasta hore loo baahan yahay.

Daroogada keeni kartaa in ay isugu soo urureen kordhay kariyaatiniin iyo HOL in serum dhiigga dadka bukaanka ah kuwaas oo lahaa stenosis ah laba-geesoodka ah ee halbowlaha kelyaha ama stenosis ee halbowlaha u ah mid ka mid ah kelyaha.

Under saameynta ay hydrochlorothiazide rizqiga hypotension, dheelitirka elektrolytka dhibtay, taas oo ah waxa lagu gartaa hoos u dhac ku wareegaya mugga dhiigga, hyponatremia, alkalosis gipohloremichesky, hypomagnesemia, hypokalemia. Saamaynta of durayo oo la faray inay sii kordhaya fiirsashada oo kolestarool ah iyo triglycerides, dulqaad kala duwanaansho ee u shaqeeyo in sonkorta taagoo, hoos u Digo of calcium kaadida, kaas oo keena in iyaga si loo kordhiyo in serum ah. Hydrochlorothiazide keeni kartaa hyperuricemia iyo turqo.

In ka kooban of diyaarinta la xoojiyey ee ka kooban lactose, oo waa u bukaanka qaba la'aan lactase enzyme isagoo galactosemia ama glucose-diid syndrome iyo galactose ah.

In marxaladaha hore ee daaweynta daawooyinka antihypertensive hoos u dhici doono ee cadaadiska iyo kooxaha wareer, taas oo xadgudub ku waxqabadka psycho-jirka ah ee jirka. Sidaa darteed, bukaannada ay shaqada ku xiran yahay dareenka korodhay in maamulka ee wadada ama adag habab, waa in loo ogaado xaaladda ay ka hor isku dayay in ay gutaan waajibaadkooda.

analogs

Ao "KRKA, bb, Novo Mesto" waa soo saaraha ah ee daroogada antihypertensive "Lorista" (kiniin). Analogs of qalab ah ee qaab-dhismeedka leeyihiin potassium ah losartan walax firfircoon. Waayo, foomamka la xoojiyey medicaments la mid ah waxay ka kooban yihiin laba qaybood oo firfircoon, potassium losartan iyo hydrochlorothiazide.

Wixii diyaarinta "Lorista" analog yeelan doonaa saameyn la mid ah antihypertensive iyo waxyeelo la mid ah. Mid ka mid ah hab oo kale waa medicament ah "Cozaar" kiniin oo ah 50 mg ama 100 potassium lozertana. saaraha waa ololaha "Merck Sharp & Dohme BV" Netherlands.

Waayo, foomamka la xoojiyey ee analoogga waa "Gizaar" iyo "sandal Gizaar." soo saaraha waa "Merck Sharp & Dohme BV" Netherlands. Kiniinada medicament at qiyaasta gadood ah qolof huruud ah calaamadda "717" on mid ka mid ah meelaha iyo halista ee horyaalka dhinaca kale, iyo murriyado gadood qiyaasta weyn dahaarka cad film-dahaarka leh kula magacaabista ah "745" hal dhinac.

Halabuurka The of medicament ah "Gizaar sandal" waa potassium losartan qadarkuu of 100 mg, iyo hydrochlorothiazide, oo ay ku qoran 12.5 mg. Diyaarinta "Gizaar" waa potassium losartan qadarkuu of 50 mg, iyo hydrochlorothiazide, oo ay ku qoran 12.5 mg.

Si ka duwan daroogada "Lorista soo taago" medicament "sandal Gizaar" waxaa ku jira nus ka mid ah hydrochlorothiazide iyo lozertana potassium dhibic. Labada daroogada leedahay tallaabo lagu durayo antihypertensive leh saamayn yar.

analog kale waa daroogada isku "Lozap daray" wax soo saarka "Zentiva AS", Czech Republic. Waxaa la soo saaray qaab kiniin kiish la Valium labada dusha dahaarka leh kula a film huruud ah iftiin. Halabuurka The of medicament leeyahay potassium losartan qadarkuu of 50 mg, iyo hydrochlorothiazide, oo ay ku qoran 12.5 mg.

Sidoo kale daroogada for "Lorista H" waa daroogada ah "Vazotenz H" wax soo saarka "Aktavis kooxaha aa", Iceland. Available in laba qaadashada. In kiniin, qiyaasta ka yar ka kooban 50 mg potassium losartan iyo hydrochlorothiazide 12.5 mg, iyo murriyado la qiyaasta weyn waxaa ku jira 100 mg of potassium losartan iyo 25 hydrochlorothiazide mg.

Reviews

Drug "Lorista" heleen reviews kala duwan. Bukaanjiifka qaar ayaa isku aragto horumar ku jira marxaladaha hore ee daaweynta, markii hoos u dhac lagu arkay dhiig karka. Qaar kale ogsoonow in la kordhiyo cadaadiska dhiigga fiidkii ama xowli ah ee dareen. In kiiska noocan oo kale ah waxaa lagama maarmaan ah si aad u joojiso daroogada daaweyn "Lorista" (kiniin). Tilmaamaha Kurtumm isku daraa qaybta "Side Effects", taas oo muujinaysa dhammaan dhacdooyinka gurracan ee suurogalka ah in laga diiwaan isticmaalka wakiilka antihypertensive.

Drug "Lorista" qaataan maalin kasta, iyadoo la isticmaalayo qiyaasta ugu yar taas oo kordhinaysa muddo sabab u habituation ah ee u shaqeeyo in walaxda firfircoon. saamayn daaweyn ma aha deg-deg ah, laakiin raasamaal ee daroogada ah ee jirka ku.