Nalidixic acid: Codsiga ee Medicine

Waxaa la og yahay in bakteeriyada waa wareer ah ugu badan ee cudurrada bararka iyo cudurada. Si aad uga takhalusi jidhka iyaga ka mid ah, iyadoo la isticmaalayo antibiotics kala duwan. Waxaa jira kooxo dhowr ah oo daroogada, kuwaas oo ficil la faray ka dhanka ah bakteeriyada. Mid ka mid ah hab oo kale waa nalidixic acid. Waa qayb firfircoon ee daawooyinka badan oo lid ku ah bakteeriyada. Mid ka mid ah tusaale ahaan - a pill "nevigramon". daroogada waxaa iska leh quinolones, koox pharmacological - antiinfectives. Inta aanad bilaabin daaweynta, waa in aad ka gudubto imtixaanka si loo ogaado pathogene iyo tijaabin ay dareen in medicament ah.

acid Nalidixic - waa maxay?

Sida xaqiiqada ah qof kasta waa la yaqaan diyaarinta ka kooban nalidixic acid. Qoraalkan waxaa horay u soo isticmaashay muddo sanado ah in daawada sida wakiilada ah anti-microbial iyo anti-Dulin. Nalidixic acid, sida kor ku xusan, waxaa loola jeedaa kooxda quinolones. Ilo Medical la xidhiidha kuwan walxaha daawooyin lid ku ah bakteeriyada. Nalidixic acid waa daawo dardaro in loo abuuray in shaybaarka. Waa budo fudud huruud ah, taas oo aan ku milmi karaan biyo. Codsiga ugu weyn ee acid - daawo. Iyadu waa xubin ka mid ah qaar ka mid ah antibiotics.

Action nalidixic acid

Si loo ogaado waxa ku hoos xaaladaha codsan nalidixic acid, waxaa lagama maarmaan ah inaad wax ka barato farsamo ee ay tallaabo. Saamaynta ugu weyn ee daroogada - waa xakamaynta koritaanka bakteeriyada iyo baabba'ooda. Its qaab hawleed waa inuu joojiyo Avv DNA by polymerization sheyga. daroogada acid nalidixic eegista dhaqmaan on Gram (-) bakteeriyada. Iyagu waa wax ku ool ka dhanka ah sheyga ee panulirus ku Proteus, Escherichia coli. Sidaa darteed, xakamaynayaan cudurada bararka, kuwaas oo ay keento bakteeriyada kuwan.

tallaabo ee daroogada ku xiran ay fiirsashada ee jirka. In yar ka qaataan, waxa ay leedahay saamayn bacteriostatic, ie, waxa uu hakiyo taranka DNA. uruureen waaweyn ee daroogada saamayn on Avv borotiinka iyo RNA. Sidaa darteed, isticmaalka muddo dheer ama maamulka kaniiniyada qaabab badan oo keentay in tallaabo bactericidal. Waa in la xusuusnaado in Gram (+) bakteeriyada iyo anaerobes waa xasaas ah in nalidixic acid. Sidaa darteed, ka hor inta aadan ku meelayn, waa in aad qabataa imtixaanka bakteeriyadda ee wax noolaha (kaadida, dhiigga) oo ku qaataan antibiotikogrammy.

Tilmaamayaasha in loo isticmaalo ee nalidixic acid

Waxaa jira noocyo kala duwan oo cudurro bararka, taas oo ka codsatay nalidixic acid. Tilmaamaha baakadda la soo saarka, si sax ah dhibcood on taas oo lagu soo diray in walaxda firfircoon ee cudurka. Si kastaba ha ahaatee, waa ku haay maanka in cuduradan waxaa aan mar walba ay keento Gram (-) flora. Sidaa darteed, marka waxtardarradoodu ee daroogada waa in la bedelaa daroogada kale ee 3 maalmood. caabuq kelyaha Xiisad - qaybaha ugu muhiimsan ee cudurrada, taas oo loo xilsaaray nalidixic acid. isticmaalka waxa ka sameysan oo ka kooban walax this, waxaa caadi ah ma aha oo kaliya in ee Kelyaha, laakiin sidoo kale in beeraha kale ee daawada. Ififaalaha ugu muhiimsan - waa:

1. Cystitis. Caabuq kaadi haysta waxaa inta badan waxa keena Escherichia coli iyo Proteus, si kastaba ha ahaatee qorayaasha quinolone isagoo oggolyahay sare ka dhanka ah sheyga kuwan.
2. Hurgumada kilyaha. Caabuq ku tubules kelyaha aad jawaab fiican u daaweynta daroogada nalidixic acid ah, gaar ahaan wajiga ba'an.
3. Garashada cudurada kaadi-mareenka. Xaaladdan oo kale, dawooyinka loo qoro si ay u manipulations urological iyo hawlgallada.
4. otitis media Ba'an.
5. Cholecystitis.
6. cudurka bararka waaweyn iyo kuwo yaryar xiidmaha (enterocolitis).
7. Urethritis iyo prostatitis.

Sidoo kale, nalidixic acid la sameyn karaa oo cudurrada kale ee ay keento garaam (-) sheyga.

Waa maxay daawooyinka ku jira nalidixic acid?

Waxaa jira alaabooyin badan oo ay ku jiraan nalidixic acid. Dhammaantood waxay leeyihiin tallaabo la mid ah oo muujinaya in loo isticmaalo. Xaaladaha qaarkood, qiyaasta kala duwan oo ah walaxda firfircoon ugu weyn. magacyo kala duwan iyo qiimaha daawooyinka, kuwaas oo ku xiran tahay dalka oo ah soo saaridda iyo shirkadda soo saarta daawada. The wakiilka ugu caansan waa "nevigramon" daroogada. daroogada waxa uu leeyahay analogues badan. Ka mid ah daawooyinkan, "Negroes", "Nalid", "Tsistidin", "Vintomilon", "Urogram" iyo kuwa kale. daroogada Kuwaas oo dhan saamayn la midka ah ee jidhka.

acid Nalidixic: tilmaamaha isticmaalka medicament ah

Diyaargaraw ka kooban nalidixic acid, in la qaado in qiyaasta a of 500 mg 3-4 jeer maalintii. Xaaladaha intooda badan, qadarka this of qayb firfircoon ku jira kaniini hal ama kaabsal. In inflammations daran qaadan kartaa 1000 mg afar jeer maalintii. In carruurta, qiyaasta waa in loo xisaabiyaa (60 mg / kg miisaankiisa jirka).

Sababo iyo waxyeelo

Like antimicrobials ugu, nalidixic acid waa u haweenka in bilaha ugu horreeya uurka iyo nuujinta. Sidoo kale, daroogada, kuwaas oo aan loo isticmaali karaa carruurta jirta ilaa 2 sano. Ka mid ah sababo kale go'doonsan kelyaha iyo yaridu cagaarshowga.

dhibaatooyinka waxaa ka mid ah shaqo caloosha xadgudub (yaaqyaaqsi, lalabo, matag), dawakhaad, iyo dareen diidmo oo xasaasiyadeed. Taxadarka waa in la isticmaalaa dadka acid nalidixic ka cabanaya heley dareemayaasha (cudurka Parkinson, qalalka, stroke).