Waa maxay automatism ee wadnaha? automaticity Wadnaha

Waa maxay automatism waxyaalaha qalbiga ku jira? Jawaabta su'aashan waxaa ku jira article hoose. Intaa waxaa dheer, waxa ku jira macluumaad ku saabsan xadgudubyada saamaynta caafimaadka dadka ee la xidhiidha fikradda la iibiyay.

Waa maxay automatism ee wadnaha?

Dunta muruqa in aadanuhu waxay leeyihiin awood ay ku dhaqmayso hoos u garaaca wadnaha looga xumaado oo markaas sequentially u wareejiyo oo dhan hoos u qaab-dhismeedka muruqa. Waxaa caddeeyeen in ay muruqa wadnaha ee go'doonka ah waa inay awoodaan inay si madaxbanaan u dhalin farax iyo sidii foosha jiibta. awoodda Tan waxa loo yaqaan wadnaha automatism.

Sababaha automaticity wadnaha

Fahmaan waxa automatism ee wadnaha, waxay noqon kartaa ka socda. qalbigiisa waxa uu leeyahay awood u gaar ah in ay curiyaan garaaca wadnaha koronto, ku xiga waxa haysta ilaa dhismeedka muruqa ah.

Guntin Sinoatrial - cluster peysmekerskih unugyada nooca ugu horeeyay (oo ay ku jiraan oo ku saabsan 40% mitochondria Itoob ku yaal myofibrils, ma T-hab ka kooban yahay tiro badan oo ah calcium free waxaa si liidata horumariyo network sarcoplasmic) oo ku yaalla derbiga midig ee cava ku vena ka xoogbadan, at kulanka of Atrium saxda ah .

Guntin waddada atrioventricular nooca labaad waxaa la aasaasay by unugyada in sameeyaan falalkooda ka Guntin ku sinoatrial, laakiin ku hoos jira xaalad gaar ah oo madax banaan dhalin amar koronto. unugyada Ku-meelgaarka ah waxaa ku jira mitochondria yar (20-30%) iyo myofibrils xoogaa ka badan gacanta ugu horeysay si. Guntin Atrioventricular ku yaalla septum ah ku dul interatrial waxaa loo wareejiyey dogob excitation iyo lugaha xidhmo laan block ah (mitochondria ka kooban 20-15%).

Dunta Purkinje yihiin soo socda kala iibsiga stage of excitation. Waxay kordhiyo qiyaastii ee maqaal qoruhu dhexe ka kasta oo ka mid ah laba laan block xidhmo. unugyada ku jira mitochondria ku saabsan 10%, ka badan qaab ahaan ka badan la mid ah macdantaa muruqa wadnaha.

muuqaalka lama filaan ah garaaca wadnaha koronto dhacdaa unugyada Guntin sinoatrial peysmekerskih, oo potentiates excitation ruxruxo madadaalo 60-80 garaac daqiiqaddiiba. Isagu waa darawalka hore si a. Markaasaa waxaa sara joogsaday ruxruxo loo gudbiyo heer-dhismeedka tabinta labaad iyo saddexaad. Waxay awoodaan inay qaadaan labada Milanello excitation iyo si madax banaan u abaari yareynta firikuwensiyada hoose yihiin. Darawalka ee heerka labaad ka dib markii Guntin atrioventricular sanka ah, oo waa inay awoodaan si ay u abuuraan gaar Siideynta ay 40-50 daqiiqo ay ka maqan yihiin waxqabad inhibitory of Guntin Dalqada wadnaha ku. Dheeraad ah, excitation ah loo kala qaado si qaab-dhismeedka xidhmada uu, kaas oo celin 30-40 garaac daqiiqaddiiba, markaas amarka korontada qubanayo in xidhmada Lugihiisu (25-30 CPM) iyo nidaamka fiber Purkinje (20 karsado daqiiqaddii) iyo galo unugyada muruqa ka shaqeeya ee myocardium ah .

Sida caadiga ah falalkooda ka Guntin awoodda sinoatrial madax bannaan si loo xakameeyo hawlaha koronto ee dhismayaasha dahsoon. Haddii dhibtay howlgalka amarka ugu horreeya ee darawalka, shuqulkiisa on links qaato taagan hoos nidaamka tabinta ah.

geeddi socodka Chemical in ay bixiyaan automaticity wadnaha

Waa maxay automatism ee wadnaha la eego chemistry? At heerka kelli, aasaas u ah dhacdo madax banaan oo mas'uul korontada (iman kara talaabada) on xuubka ku peysmekerskih unugyada waa joogitaanka wax-u impulsatora. Shuqulkiisa (qalbiga automatism function) waxay ka kooban tahay saddex marxaladood.

Marxaladaha impulsatora:

• wajigii 1aad diyaarinta (superoxide by dhexgalka ee oxygen la phospholipids wanaagsan eedeeyay on xuub dusha unugyada peysmekerskoy waxay keensataa amar diidmo ah, waxay siinaysaa awood u nasasiiyay);
• potassium 2aad wajiga iyo sodium gaadiid firfircoon, inta lagu guda jiro kaas oo mas'uul dibadda ee unug uu noqdo siman ilaa 30 MW,
• Wajiga 3aad electrochemical boodi - isticmaalayo tamarta ahaan inta lagu guda jiro dib u warshadaynta ee noocyada ogsijiin Waxyeelo (Hawada Oksijiinka oo ionized oo hydrogenperoxid ah) iyadoo la isticmaalayo ensaymes catalase iyo dismutase superoxide. Sababay quanta tamarta pacemaker biocapacity kordhay si ay u sababa iman kara tallaabo ah.

Maaraysa unugyada wadnaha dhalin - pacemakers daruuri ka dhacaan xaaladaha hortiisa ku filan oo oxygen kelli, kaas oo u dhiibay darina erythrocytes inflowing dhiigga.

Yaraynta shaqada ama joojinta qayb ka mid ah hawlgalka ka mid ah ama ka badan marxaladaha impulsatora nidaamka ku xadgudba unugyada peysmekerskih shaqo ku heshiiyeen, taasoo keenta arrhythmia. Joojinta mid ka mid ah geedi socodka nidaamka this sababa wadnaha lama filaan ah. Ogaaday automatism in sida qalbiga ku jira, fahmi karo iyo habka.

Saamaynta habdhiska ku autonomic in muruqa wadnaha

Intaa waxaa dheer in ay awood u gaar ah si ay falalkooda korontada, shaqada wadnaha signallo ka muruqa ah innervating dareemayaasha oo garawsi iyo parasympathetic, on failure kuwaas oo daciifin laga yaabaa automaticity wadnaha.

Saamaynta horyaalka dabacsanaadaan dadajiyaa qalbi ah, waxay leedahay saamayn dhiirrigelin. innervation dabacsanaadaan leeyahay chronotropic, inotropic, saamayn dromotropic wanaagsan.

Under tallaabada jirta ee nidaamka parasympathetic neerfayaasha , unugyada peysmekerskih depolarization deceleration (action inhibitory), iyo halkan gaabis ah heerka wadnaha (action chronotropic negative), hoos u dhac conductivity gudaha qalbiga ku jira (saamayn dromotropic negative), hoos u dhac in foosha systolic tamarta (saamayn inotropic negative), laakiin excitability sare ee wadnaha ee (action batmotroponoe positive). Arintaan ayaa sidoo kale u qaatay sida xadgudub ku ah shaqada automaticity wadnaha.

Sababaha automatism wadnaha

1. ischemia myocardial infarction.
2. Caabuq.
3. Sarkhaan.
4. Xadgudubka sodium dheelitirka, potassium, magnesium, calcium.
5. cillad hormoon ah.
6. Ku xadgudubka saameynta ay ku dhammaato oo garawsi iyo parasympathetic goboleedka.

Noocyada garaaca ay sabab u tahay xadgudubyada automaticity waxyaalaha qalbiga ku jira

1. Sanqaroorka tachy-iyo bradycardia.
2. Neefsashada (dhalinyarada) arrhythmia.
3. arrhythmia Extrasystole (sanka, wadne, atrioventricular, ventricular).
4. tachycardia Paroxysmal.

Kala arrhythmia ay sabab u tahay xanuunada tabinta automaticity iyo laabashadu si ay u sameeyaan hirarka (ruxruxo laabashada) in mid ama ka badan oo gaar ah qaybo ka mid ah waxyaalaha qalbiga ku jira, natiijadu waa aamba ama flutter wadne.

aamba Ventricular - mid ka mid ah garaaca naf-gooyada ah inta badan, taas oo ah natiijo ah oo wadnaha lama filaan ah iyo dhimasho. Habka ugu waxtarka badan ee daaweynta - Rogidda korontada.

gunaanad

Sidaas tixgeliyo, waxa automatism ee wadnaha, fahmi karaa waxa xadgudubyada waa u suurtoobaan in ay dhacdo jirro. Tani, ka bacdi, waxay fursad si ay ula dagaalamaan hababka cudurka wanaagsan oo wax ku ool ah.