Amyloidosis - waa maxay? Amyloidosis: sababaha, calaamadaha, daaweynta, cudurka

Amyloidosis - waa maxay? Waa cudur-shiid protein ah oo formation iyo dhigaalka ee unugyada kala duwan iyo xubnaha walax gaar ah protein-polysaccharide - amyloid.

Horumarinta cudurka

In la sameeyo amyloidosis (waxa ay tahay - aynu hore u aragnay) xadgudub ku ah Avv borotiinka nidaamka reticuloendothelial. The plasma waa raasamaal ah borotiinada aan caadi ahayn. borotiinada Kuwani muhiimad ahaan waa cudur is waxayna keeni xasaasiyad la mid ah formation of autoantibodies.

Markaas, kuwaas unugyada cudur iyo fal borotiinada grubodispersionnye soo dadajin. Tan iyo markii formation of amyloid. Macluumaadkaan waxaa lagu shubo on darbiyada markabka iyo xubnaha kala duwan. Tartiib tartiib aruursaday, amyloid kaxeeya xagga dhimashada jidhka.

Noocyada amyloidosis. sababaha

Waxaa jira dhawr nooc oo ah amyloidosis. Sababaha cudurka waa si toos ah ay ku xidhan tahay nooca waxa of amyloidosis. Waa maxay? Qoondaynta waxaa lagu fuliyaa sida ay protein aasaasiga ah, taas oo ka kooban fibrils amyloid. Hoos waxaa ku qoran views cudurka.

1. amyloidosis Primary (AL-amyloidosis). Marka dhinaca horumarinta ee plasma muuqan silsilado immunoglobulin iftiinka aan caadi ahayn, kaas oo ay awoodaan si ay u degaan ee unugyada kala duwan ee jidhka. Sidoo kale bedelay inta lagu guda jiro unugyada plasma of myeloma, macroglobulinemia Waldenström ee, hypergammaglobulinemia monoclonal.
2. amyloidosis Sare (AA-amyloidosis). Xaaladdan oo kale waxaa jira in la sii daayo xad-dhaafka ah protein beerka Alfa-globulin. Tani protein marxaladda ba'an in uu ku dhexsameeysmo bararka joogtada ah. Tani waa suurto gal ah in cudurro kala duwan, sida rheumatoid arthritis, duumada, bronchiectasis, osteomyelitis, baraska, qaaxada.
3. amyloidosis Qoyska (AF-amyloidosis). Waa cudur la iska dhaxlo la dhaxal recessive autosomal. Waxaa sidoo kale loo yaqaannaa qandhada Mediterranean qoyska go'aysa ama paroxysmal poliserozita. Muujiyeen cudurkan weerar of qandho, dhacdo ee calool xanuun, finan maqaarka, arthritis, iyo pleurisy.
4. amyloidosis dialysis The (AH-amyloidosis). Waxay ku xiran yahay xaqiiqada ah in protein beta-2 microglobulin MHC in dad caafimaad qaba ayaa la takhalusin by kelyaha, iyo waxa aan la sifeeyo ee kelyaha, iyo sidaas oo waa raasamaal ee jirka.
5. AE-amyloidosis. Waxaa la soo koraya noocyo ka mid ah kansarka, sida thyroid.
6. amyloidosis neefo.

calaamadaha

Marka cudurka calaamadaha "Amyloidosis" ku xiran deegaamaynta ee kayd. Iyada oo guuldaradii of mareenka caloosha iyo mindhicirka oo laga dheehan karo carrabka balaartay, function liqidda oo yaraada, calool engeg ama shuban. Waxaa laga yaabaa in lacag dhigaal ah buro-amyloid mindhicirka ama caloosha.

amyloidosis xiidmaha Ulasocto dareen ah baroor iyo raaxo laga yaabaa in calool xanuun khafiif ah. Haddii by ganaca ku dhuftay, waa bandhigaan calaamado la mid ah sida in pankreatit. Haddii dhaawac beerka arkay midhihiisa, lalabo, belching, matag, qalal, joonis.

neefsashada Amyloidosis u muuqataa sida soo socota:

• cod xabeeb;
• astaamaha boronkiitada,
• amyloidosis buro pulmonary.

Calaamadaha soo socda ee amyloidosis of habka dareemayaasha dhici kara:

• jidhidhico, ama dareen in addimada, kabuubyo (polyneuropathy durugsan) gubanaya;
• madax xanuun, wareer,
• xanuunada endetarms- (Xukun la'aanta kaadida, saxarada).

Amyloidosis - waxa uu yahay, sababaha iyo calaamadaha ay aannu dib u eegid. Hadda waxaan eegeynaa sida cudurka laga helo iyo waxa hababka daaweynta jira.

Baadhista xanuunada

In cudurka noocan oo kale ah sida amyloidosis, cudurka waa mid adag. Magacaabay cilmi shaybaarka iyo hardware ah.

In waxbarashada shaybaarka, dib u eegis guud ee dhiigga lagu arkay korodhka ESR, leukocytes iyo hoos u dhiig xinjirowga. Falanqaynta guud ee protein kaadida waxa ay joogtaa Texas - dhululubada, leukocytes iyo erythrocytes. In coprogram bandhigaan xaddi badan oo istaarijka, baruurta iyo murqaha macdantaa. In Kiimikada noole dhiig lesions beerka ku muujiyey ah ee kolestaroolka, bilirubin, phosphatase xumadoodu soo kordha.

In amyloidosis aasaasiga ah ee kaadida iyo dhiigga plasma tusay content sare ah amyloid. Marka sare lagu jiro baaritaan sheybaar muujinayaan calaamadaha caabuq chronic.

Sidoo kalena inay fuliso tallaabooyin kale ogaanshaha:

• Baaritaanka X-ray,
• echocardiography (in ay dhacdo weerar wadnaha looga shakisan yahay);
• assays functional la formaldehyde,
• meydadka biopsy.

daaweynta

Marka cudurka waxaa lagu fuliyaa daaweynta bukaan-. Amyloidosis, taas oo ay jiraan xaalado daran, sida kelyaha chronic ama wadnaha oo shaqadiisa gaba daran daweeyo isbitaal.

In amyloidosis aasaasiga ah hore u magacaabay daawooyin sida "Chloroquine" "Melphalan" "prednisolone", "Colchicine".

In amyloidosis sare daweeyo cudurka sababaya, tus, osteomyelitis, qaaxada, pleural empyema et al., All calaamadaha amyloidosis inta badan baaba'aa ka dib daawo.

Haddii cudurka uu yeesho sabab u ah kelyaha sifeeya kelyaha, ka dibna bukaanka noocan oo kale ah waxaa loo wareejiyey saarista xuubka hoose.

In the case of galalka shuban loo isticmaalo daawooyinka, sida "subnitrate bismuth," ama adsorbing wakiilka.

Waxay sidoo kale waxaa laga yaabaa in daaweyn astaamaha:

• diyaarinta yareeyo cadaadiska;
• vitamins, diuretics;
• shubo plasma, iwm

Intaas waxaa sii dheer, waxaa laga yaabaa in lagu dabaqo iyo daaweynta qalliin. amyloidosis of caajisnimo ah waxaa laga yaabaa in Dumayn ka dib saarida ee xubinta. Xaaladaha intooda badan, tani waxay keenaysaa in horumar laga gaaray xaaladda bukaanka iyo in la yareeyo formation of amyloid.

cuntada

Amyloidosis u baahan yahay cunto joogto ah. Iyadoo horumarinta cudurka chronic kelyaha waa in la xaddido qaadashada cusbo, iyo cuntooyinka borotiinka sida hilibka, kaluunka, ukunta. Haddii horumarinta chronic wadnaha, waa in laga joojiyaa cunto cusbo, sigaarka iyo cuntooyinka pickled.

amyloidosis wadnaha

Cudurka waxaa sidoo kale loo yaqaan cardiomyopathy amyloid. Iyada oo uu horumarka dhigaalka amyloid ku dhici kara myocarditis, pericarditis, endocarditis, ama darbiyada ku quseyo iyo halbowleyaasha wadnaha. Sababta cudurka wadnaha this waxaa laga yaabaa in amyloidosis aasaasiga ah, dugsiga sare ama qoyska. Inta badan amyloidosis waxyaalaha qalbiga ku jira - ma aha cudur cidlo ah, oo waxaa la soo koraya ee isku midka ah la amyloidosis ee sambabada, kelyaha, xiidmaha ama beeryarada.

Calaamadaha amyloidosis wadnaha

Inta badan calaamadaha cudurkan la mid tahay cardiomyopathy hypertrophic ama wadne xanuunka. Marka marxaladdan hore, astaamaha caddayn. Waxaa laga yaabaa in ay la kulmaan caro iyo daal, qaar ka mid ah miisaanka oo yaraada, barar unugyo iyo wareer.

Kasii af badan sida caadiga ah dhacdaa ka dib stress ama caabuq-mareenka. Ka dib markii in sida caadiga ah u muuqan wadnaha xanuun nooc-kog, arrhythmia, barar fahmayaan, dyspnea, wayneeyo beerka. Cadaadiska dhiigga waxaa badanaa lagu hoos.

Cudurku wuxuu si degdeg ah uga sii darayo, iyo muujinta kala waa iska caabin ah (iska caabin) si therapy. Xaaladaha daran, bukaanada la kulmi karaan ascites (raasamaal ah ee dareeraha in saabka caloosha) ama effusion pericardial. Sababo la dhexgalay amyloid ku horumariyaan bradycardia sanka. Tani waxay keeni kartaa dhimasho kedis ah.

Odoroska

Xudunta amyloidosis saadaal saboolka ah. Hawshiisa wadnaha ee cudurkan si tartiib ah uga sii darayo iyo dhimasho waa dhow. In Russia ma jiro xarumo gaar ah wax ka qabashada arrintan.